ES2068999T3 - Composiciones para la liberacion retardada de clorhexidina. - Google Patents

Composiciones para la liberacion retardada de clorhexidina.

Info

Publication number
ES2068999T3
ES2068999T3 ES90302837T ES90302837T ES2068999T3 ES 2068999 T3 ES2068999 T3 ES 2068999T3 ES 90302837 T ES90302837 T ES 90302837T ES 90302837 T ES90302837 T ES 90302837T ES 2068999 T3 ES2068999 T3 ES 2068999T3
Authority
ES
Spain
Prior art keywords
compositions
chlorhexidine
release
delayed release
sustained
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90302837T
Other languages
English (en)
Inventor
Michael Friedman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yissum Research Development Co of Hebrew University of Jerusalem
Original Assignee
Yissum Research Development Co of Hebrew University of Jerusalem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Research Development Co of Hebrew University of Jerusalem filed Critical Yissum Research Development Co of Hebrew University of Jerusalem
Application granted granted Critical
Publication of ES2068999T3 publication Critical patent/ES2068999T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0063Periodont
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00Preparations for dentistry
    • A61K6/50Preparations specially adapted for dental root treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)

Abstract

COMPOSICIONES DE REPOSICION SOSTENIDA BIODEGRADABLES CAPACES DE ALCANZAR LA REPOSICION SOSTENIDA DE LA CLORHEXIDINA, COMPRENDEN GLUCANATOS DE CLOHEXIDINA, UNA PROTEINA COMO ES LA GELATINA (QUE DEBE SER ENLAZADA EN CURZ) Y OPCIONALMENTE UN PLASTICIDA COMO LA GLICERINA. LAS COMPOSICIONES PUEDEN SER FORMADAS EN DISPOSITIVOS DE IMPLANTE QUE PUEDEN SER USADOS PARA TRATAR UNA AMPLIA VARIEDAD DE ENFERMEDADES Y CONDICIONES. LOS IMPLANTES SON ESPECIALMENTE UTILES EN EL TRATAMIENTO DE ENFERMEDADES TALES COMO LAS PERIODENTALES Y AQUELLAS QUE REQUEREN UNA REPOSICION DE DROGAS PROLONGADA.
ES90302837T 1989-03-16 1990-03-16 Composiciones para la liberacion retardada de clorhexidina. Expired - Lifetime ES2068999T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/324,505 US5002769A (en) 1987-03-13 1989-03-16 Compositions for the sustained-release of chlorhexidine

Publications (1)

Publication Number Publication Date
ES2068999T3 true ES2068999T3 (es) 1995-05-01

Family

ID=23263888

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90302837T Expired - Lifetime ES2068999T3 (es) 1989-03-16 1990-03-16 Composiciones para la liberacion retardada de clorhexidina.

Country Status (9)

Country Link
US (1) US5002769A (es)
EP (1) EP0388220B1 (es)
JP (1) JP2960098B2 (es)
AT (1) ATE119391T1 (es)
AU (1) AU621521B2 (es)
CA (1) CA2011637C (es)
DE (1) DE69017484T2 (es)
DK (1) DK0388220T3 (es)
ES (1) ES2068999T3 (es)

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IL97771A (en) * 1991-04-04 1996-12-05 Sion Narrow Weaving Dry polymeric material having antimicrobial activity
US5385606A (en) * 1992-07-06 1995-01-31 Kowanko; Nicholas Adhesive composition and method
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US6015844A (en) * 1993-03-22 2000-01-18 Johnson & Johnson Medical, Inc. Composite surgical material
GB2280850B (en) * 1993-07-28 1997-07-30 Johnson & Johnson Medical Absorbable composite materials for use in the treatment of periodontal disease
GB9402877D0 (en) * 1994-02-15 1994-04-06 Torchinsky Alick Mouthwash
ATE240737T1 (de) * 1996-02-14 2003-06-15 Itzhak Binderman Topische bisphosphonate zur verhinderung der knochenresorption
US6117856A (en) * 1996-02-14 2000-09-12 Binderman; Itzhak Topical bisphosphonates for prevention of bone resorption
US6197331B1 (en) 1997-07-24 2001-03-06 Perio Products Ltd. Pharmaceutical oral patch for controlled release of pharmaceutical agents in the oral cavity
DE19813686A1 (de) * 1998-03-27 1999-09-30 Roeko Gmbh & Co Antibakteriell wirksames Mittel zur Behandlung oder zum Füllen von Wurzelkanälen und Herstellungsverfahren
US7074426B2 (en) * 2002-03-27 2006-07-11 Frank Kochinke Methods and drug delivery systems for the treatment of orofacial diseases
US10098981B2 (en) 2002-08-06 2018-10-16 Baxter International Inc. Biocompatible phase invertable proteinaceous compositions and methods for making and using the same
US9101536B2 (en) 2002-08-06 2015-08-11 Matrix Medical Llc Biocompatible phase invertable proteinaceous compositions and methods for making and using the same
US20040053201A1 (en) * 2002-09-17 2004-03-18 Dovgan Joseph S. Antibacterial sponges for use in endodontic procedures and methods of use
US20040136926A1 (en) * 2002-11-08 2004-07-15 Periathamby Antony Raj Intra-oral drug delivery system
US20040185009A1 (en) * 2003-03-19 2004-09-23 Dexcel Pharma Technologies Ltd. Composition and device for treating periodontal diseases
US20050036955A1 (en) * 2003-08-13 2005-02-17 Degould Michael D. Bioresorbable tooth extraction socket dressing
US20070213768A1 (en) * 2003-10-21 2007-09-13 Irena Wasserman Compositions and Devices Including Same Useful for Anastomosis
US7678767B2 (en) 2004-06-16 2010-03-16 Pneumrx, Inc. Glue compositions for lung volume reduction
US20060002970A1 (en) * 2004-07-01 2006-01-05 Aspenberg Per V Method for coating a suture
US20060275230A1 (en) 2004-12-10 2006-12-07 Frank Kochinke Compositions and methods for treating conditions of the nail unit
TW200637618A (en) * 2004-12-10 2006-11-01 Talima Therapeutics Inc Compositions and methods for treating conditions of the nail unit
FR2896057A1 (fr) * 2006-01-12 2007-07-13 St Microelectronics Sa Procede et dispositif de generation d'un nombre aleatoire dans un peripherique usb
US20070160559A1 (en) * 2006-01-12 2007-07-12 Roszell James A Skin disinfectant composition and methods for using
JP5462000B2 (ja) * 2007-02-09 2014-04-02 デンツプライ インターナショナル インコーポレーテッド 水系材料を用いた歯髄及び充填される根管の処置方法
EP1961411A1 (en) * 2007-02-21 2008-08-27 FUJIFILM Manufacturing Europe B.V. A controlled release composition
EP1961414A1 (en) * 2007-02-21 2008-08-27 FUJIFILM Manufacturing Europe B.V. A controlled release composition comprising a recombinant gelatin
EP2112999B1 (en) * 2007-02-21 2012-03-28 FUJIFILM Manufacturing Europe B.V. Non-natural recombinant gelatins with enhanced functionality
US20080241795A1 (en) * 2007-03-26 2008-10-02 Block James C Prevention and treatment of alveolar osteitis
US9468510B2 (en) 2008-03-24 2016-10-18 Richard J. Shaw Floss device, a method of forming the floss device and a method of using the floss device
US8541047B1 (en) 2008-03-24 2013-09-24 Richard J. Shaw Polar antiseptic/antibacterial containing toothpick probes
EP2324864A4 (en) * 2008-09-08 2013-12-18 Nat Inst For Materials Science COMPOSITE MATERIAL WITH A MATRIX OF HIGH MOLECULAR WEIGHT AND A COMPOUND OF LOW MOLECULAR WEIGHT AND METHOD FOR THE PRODUCTION THEREOF
WO2010091274A1 (en) * 2009-02-06 2010-08-12 Skinvisible Pharmaceuticals, Inc. A cationic pharmaceutically active ingredient containing composition, and methods for manufacturing and using
US9650684B2 (en) * 2009-05-22 2017-05-16 The Trustees Of The University Of Pennsylvania Methods of identifying and using general or alternative splicing inhibitors
WO2011103440A1 (en) * 2010-02-19 2011-08-25 Skinvisible Pharmaceuticals, Inc. Skin disinfectant composition and methods for manufacturing and using
US8865198B2 (en) 2010-10-25 2014-10-21 Dexcel Pharma Technologies Ltd. Method for treating a periodontal disease
DE102012001979A1 (de) 2012-02-02 2013-08-08 Voco Gmbh Härtbares Gemisch umfassend Weichmacher mit einem polyalicyclischen Strukturelement zur Anwendung bei der Herstellung dentaler Werkstoffe
DE102012001978A1 (de) 2012-02-02 2013-08-08 Voco Gmbh Dentale Kompositmaterialien enthaltend tricyclische Weichmacher
EP2956110B1 (en) * 2013-02-14 2020-08-12 DENTSPLY SIRONA Inc. Resorbable and curable compositions for use in dentistry
RU2015143995A (ru) 2013-03-14 2017-04-20 Халлюкс, Инк. Способ лечения инфекций, заболеваний или расстройств ногтевого ложа
EP3003285B1 (en) * 2013-06-03 2022-02-16 McNeil AB Solid pharmaceutical dosage form for release of at least two active pharmaceutical ingredients in the oral cavity
SG11201604596RA (en) * 2013-12-12 2016-07-28 Innovation Technologies Inc Materials and methods for controlling infections
DE202014101882U1 (de) 2014-04-22 2014-05-02 Armin Armani Orales Abgabesystem
CZ308891B6 (cs) * 2014-10-01 2021-08-11 Wald Pharmaceuticals s.r.o Aplikační směs pro zvýšení účinnosti antiseptik a/nebo dezinficiens, aplikační prostředek obsahující aplikační směs, a použití této směsi
CN111867568A (zh) 2018-01-18 2020-10-30 C·阿尔诺德 包含聚已缩胍的口香糖组合物
DE102019000321A1 (de) 2019-01-14 2020-07-16 Beuth Hochschule Für Technik Berlin Orale Polymerzusammensetzung mit verzögerter Freisetzung
DE102019000322A1 (de) 2019-01-14 2020-07-16 Beuth Hochschule Für Technik Berlin Polymerzusammensetzung mit antiseptischen Eigenschaften und Verfahren zur Herstellung
CN110124099B (zh) * 2019-06-14 2022-01-11 四川涑爽医疗用品有限公司 一种长效抑菌的复配牙周塞治剂及其制备方法
DE102019122174A1 (de) 2019-08-19 2021-02-25 Voco Gmbh Dentale polymerisierbare Zusammensetzung auf der Basis kondensierter Silane
DE102020007979A1 (de) 2020-12-29 2022-06-30 Charité Universitätsmedizin Institut für Mikrobiologie und Infektionsimmunologie Zusammensetzung zur Behandlung von lnfektionen mit Coronaviren

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US2961374A (en) * 1950-10-14 1960-11-22 Lieb Hans Injectable pharmaceutical preparation, and a method of making same
US3642003A (en) * 1969-08-26 1972-02-15 Sutures Inc Sutures having long-lasting germicidal properties
US3956480A (en) * 1974-07-01 1976-05-11 Colgate-Palmolive Company Treatment of teeth
US4344967A (en) * 1979-08-07 1982-08-17 Devro, Inc. Film forming composition and uses thereof
US4568535A (en) * 1982-08-06 1986-02-04 Loesche Walter J Composition for periodontal administration
JPS59222406A (ja) * 1983-06-01 1984-12-14 Teijin Ltd 歯周疾患治療用製剤及びその製造法
US4758595A (en) * 1984-12-11 1988-07-19 Bausch & Lomb Incorporated Disinfecting and preserving systems and methods of use
FR2591892B1 (fr) * 1985-12-23 1988-09-16 Pf Medicament Association collagene/principe actifantiseptique et/ou anti-inflammatoire a titre de composition, son procede de preparation et son utilisation pour la fabrication d'une composition pharmaceutique
JPS62223115A (ja) * 1986-03-25 1987-10-01 Rooto Seiyaku Kk 歯周病治療剤
IL78826A (en) * 1986-05-19 1991-05-12 Yissum Res Dev Co Precursor composition for the preparation of a biodegradable implant for the sustained release of an active material and such implants prepared therefrom

Also Published As

Publication number Publication date
EP0388220B1 (en) 1995-03-08
EP0388220A3 (en) 1991-03-13
JP2960098B2 (ja) 1999-10-06
US5002769A (en) 1991-03-26
EP0388220A2 (en) 1990-09-19
AU5118990A (en) 1990-09-20
ATE119391T1 (de) 1995-03-15
DE69017484D1 (de) 1995-04-13
CA2011637A1 (en) 1990-09-16
DK0388220T3 (da) 1995-03-27
CA2011637C (en) 2001-01-30
AU621521B2 (en) 1992-03-12
JPH03200726A (ja) 1991-09-02
DE69017484T2 (de) 1995-07-27

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