CA1335816C - 4-pyridyl-1,3-dioxan-5-ylalkenoic acid derivatives - Google Patents
4-pyridyl-1,3-dioxan-5-ylalkenoic acid derivativesInfo
- Publication number
- CA1335816C CA1335816C CA000590484A CA590484A CA1335816C CA 1335816 C CA1335816 C CA 1335816C CA 000590484 A CA000590484 A CA 000590484A CA 590484 A CA590484 A CA 590484A CA 1335816 C CA1335816 C CA 1335816C
- Authority
- CA
- Canada
- Prior art keywords
- formula
- compound
- pyridyl
- phenyl
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB888803516A GB8803516D0 (en) | 1988-02-16 | 1988-02-16 | Heterocyclic compounds |
GB8803516 | 1988-02-16 | ||
GB888824666A GB8824666D0 (en) | 1988-10-21 | 1988-10-21 | Pyridine derivatives |
GB8824666.5 | 1988-10-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA1335816C true CA1335816C (en) | 1995-06-06 |
Family
ID=26293498
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA000590484A Expired - Fee Related CA1335816C (en) | 1988-02-16 | 1989-02-08 | 4-pyridyl-1,3-dioxan-5-ylalkenoic acid derivatives |
Country Status (24)
Country | Link |
---|---|
US (1) | US5166213A (xx) |
EP (1) | EP0329360B1 (xx) |
JP (1) | JP2812697B2 (xx) |
KR (1) | KR0145725B1 (xx) |
CN (1) | CN1040753C (xx) |
AR (1) | AR246965A1 (xx) |
AT (1) | ATE109478T1 (xx) |
AU (1) | AU626534B2 (xx) |
CA (1) | CA1335816C (xx) |
DE (1) | DE68917170T2 (xx) |
DK (1) | DK66989A (xx) |
ES (1) | ES2057104T3 (xx) |
FI (1) | FI93216C (xx) |
GB (1) | GB8901201D0 (xx) |
HU (1) | HU209700B (xx) |
IE (1) | IE63825B1 (xx) |
IL (1) | IL89214A (xx) |
MY (1) | MY103699A (xx) |
NO (1) | NO172491C (xx) |
NZ (1) | NZ227880A (xx) |
PH (1) | PH26227A (xx) |
PL (1) | PL158201B1 (xx) |
PT (1) | PT89703B (xx) |
ZW (1) | ZW1789A1 (xx) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8709794D0 (en) * | 1987-04-24 | 1987-05-28 | Ici Plc | Heterocyclic acids |
IE81170B1 (en) * | 1988-10-21 | 2000-05-31 | Zeneca Ltd | Pyridine derivatives |
GB9021571D0 (en) * | 1990-10-04 | 1990-11-21 | Ici Plc | Heterocyclic acids |
RU2449999C2 (ru) * | 2006-01-18 | 2012-05-10 | Эвольва Са | Модуляторы ppar |
MX2009007670A (es) * | 2007-01-18 | 2011-11-18 | Evolva Sa | 1,3-dioxanos sustituidos utiles como moduladores de paar. |
WO2008089463A2 (en) * | 2007-01-18 | 2008-07-24 | Evolva Sa | Substituted 1,3-dioxanes and their uses |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0062238B1 (de) * | 1981-03-30 | 1985-01-30 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | 1,3-Dioxolan-Derivate, Herstellung dieser Verbindungen, fungizide Mittel, die diese Verbindungen als Wirkstoffe enthalten sowie Verwendung solcher Verbindungen bzw. Mittel zur Bekämpfung von Fungi in der Landwirtschaft und im Gartenbau |
GB8310407D0 (en) * | 1982-05-12 | 1983-05-25 | Ici Plc | 1 3 - dioxan -5- ylalkenoic acids |
GB8330094D0 (en) * | 1983-11-11 | 1983-12-21 | Ici Plc | Diphenyl compounds |
GB8330120D0 (en) * | 1983-11-11 | 1983-12-21 | Ici Plc | Chemical process |
GB8330099D0 (en) * | 1983-11-11 | 1983-12-21 | Ici Plc | Cycloalkane derivatives |
US4554011A (en) * | 1984-08-24 | 1985-11-19 | Chevron Research Company | Herbicidal 2S-(2β,4β,5β)-5-Arylmethoxy-4-substituted 2-alkyl-1,3-dioxane derivatives |
GB8511891D0 (en) * | 1985-05-10 | 1985-06-19 | Ici Plc | Alkenoic acids |
GB8511892D0 (en) * | 1985-05-10 | 1985-06-19 | Ici Plc | Fluoralkane derivatives |
GB8511890D0 (en) * | 1985-05-10 | 1985-06-19 | Ici Plc | Benzene derivatives |
HU198706B (en) * | 1985-05-10 | 1989-11-28 | Ici Plc | Process for producing 1,3-dioxan-ethers and pharmaceutical compositions containing them |
GB8511895D0 (en) * | 1985-05-10 | 1985-06-19 | Ici Plc | Heterocyclic compounds |
GB8511894D0 (en) * | 1985-05-10 | 1985-06-19 | Ici Plc | Phenol derivatives |
DE3685775T2 (de) * | 1985-05-10 | 1993-01-21 | Ici Plc | Alkenderivate. |
GB8611174D0 (en) * | 1986-05-08 | 1986-06-18 | Ici Plc | Amide derivatives |
ES2017633B3 (es) * | 1985-11-12 | 1991-03-01 | Ici Plc | Amido derivados. |
GB8531892D0 (en) * | 1985-12-30 | 1986-02-05 | Ici Plc | Carboxylic acids |
GB8626296D0 (en) * | 1986-11-04 | 1986-12-03 | Ici Plc | Therapeutic agents |
GB8626297D0 (en) * | 1986-11-04 | 1986-12-03 | Ici Plc | Pharmaceutical compositions |
GB8709794D0 (en) * | 1987-04-24 | 1987-05-28 | Ici Plc | Heterocyclic acids |
IE81170B1 (en) * | 1988-10-21 | 2000-05-31 | Zeneca Ltd | Pyridine derivatives |
-
1989
- 1989-01-19 GB GB898901201A patent/GB8901201D0/en active Pending
- 1989-02-07 NZ NZ227880A patent/NZ227880A/xx unknown
- 1989-02-07 IL IL8921489A patent/IL89214A/en not_active IP Right Cessation
- 1989-02-07 IE IE39289A patent/IE63825B1/en not_active IP Right Cessation
- 1989-02-08 CA CA000590484A patent/CA1335816C/en not_active Expired - Fee Related
- 1989-02-13 ES ES89301334T patent/ES2057104T3/es not_active Expired - Lifetime
- 1989-02-13 HU HU89632A patent/HU209700B/hu not_active IP Right Cessation
- 1989-02-13 PL PL1989277709A patent/PL158201B1/pl unknown
- 1989-02-13 AU AU29908/89A patent/AU626534B2/en not_active Ceased
- 1989-02-13 DK DK066989A patent/DK66989A/da not_active Application Discontinuation
- 1989-02-13 JP JP1031263A patent/JP2812697B2/ja not_active Expired - Lifetime
- 1989-02-13 PH PH38187A patent/PH26227A/en unknown
- 1989-02-13 EP EP89301334A patent/EP0329360B1/en not_active Expired - Lifetime
- 1989-02-13 FI FI890678A patent/FI93216C/fi not_active IP Right Cessation
- 1989-02-13 ZW ZW17/89A patent/ZW1789A1/xx unknown
- 1989-02-13 PT PT89703A patent/PT89703B/pt active IP Right Grant
- 1989-02-13 NO NO890607A patent/NO172491C/no unknown
- 1989-02-13 KR KR1019890001661A patent/KR0145725B1/ko not_active IP Right Cessation
- 1989-02-13 CN CN89100858A patent/CN1040753C/zh not_active Expired - Fee Related
- 1989-02-13 AT AT89301334T patent/ATE109478T1/de not_active IP Right Cessation
- 1989-02-13 DE DE68917170T patent/DE68917170T2/de not_active Expired - Fee Related
- 1989-02-14 US US07/310,235 patent/US5166213A/en not_active Expired - Fee Related
- 1989-02-14 AR AR89313211A patent/AR246965A1/es active
- 1989-02-16 MY MYPI89000189A patent/MY103699A/en unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US5053415A (en) | Pyridine derivatives | |
CA1335816C (en) | 4-pyridyl-1,3-dioxan-5-ylalkenoic acid derivatives | |
US4895962A (en) | 2,4-diphenyl-1,3-dioxanes | |
US4921866A (en) | 1,3-dioxanes | |
US5401849A (en) | 4-pyridyl-1,3-dioxane derivatives | |
US4908380A (en) | Pharmaceutical compositions | |
KR100191763B1 (ko) | 헤테로시클릭산 | |
RU2040525C1 (ru) | 1,3-дииоксаноновые производные алкеновой кислоты или их фармацевтически приемлемая соль | |
EP0228887B1 (en) | Dioxane hexenoic acids |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MKLA | Lapsed |