CA1313485C - Detection de sequences d'acides nucleiques utilisant l'agglutination des particules - Google Patents

Detection de sequences d'acides nucleiques utilisant l'agglutination des particules

Info

Publication number
CA1313485C
CA1313485C CA000530996A CA530996A CA1313485C CA 1313485 C CA1313485 C CA 1313485C CA 000530996 A CA000530996 A CA 000530996A CA 530996 A CA530996 A CA 530996A CA 1313485 C CA1313485 C CA 1313485C
Authority
CA
Canada
Prior art keywords
nucleic acid
particles
acid sequences
sample
bound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA000530996A
Other languages
English (en)
Inventor
Malcolm L. Gefter
Christie A. Holland
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cambridge Biotech Corp
Original Assignee
Cambridge Bioscience Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cambridge Bioscience Corp filed Critical Cambridge Bioscience Corp
Application granted granted Critical
Publication of CA1313485C publication Critical patent/CA1313485C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA000530996A 1986-03-04 1987-03-03 Detection de sequences d'acides nucleiques utilisant l'agglutination des particules Expired - Fee Related CA1313485C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83610086A 1986-03-04 1986-03-04
US836,100 1986-03-04

Publications (1)

Publication Number Publication Date
CA1313485C true CA1313485C (fr) 1993-02-09

Family

ID=25271242

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000530996A Expired - Fee Related CA1313485C (fr) 1986-03-04 1987-03-03 Detection de sequences d'acides nucleiques utilisant l'agglutination des particules

Country Status (4)

Country Link
EP (1) EP0259453A1 (fr)
JP (1) JPS63502875A (fr)
CA (1) CA1313485C (fr)
WO (1) WO1987005334A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL85551A0 (en) * 1987-04-01 1988-08-31 Miles Inc Rapid hybridization assay and reagent system used therein
US5124246A (en) * 1987-10-15 1992-06-23 Chiron Corporation Nucleic acid multimers and amplified nucleic acid hybridization assays using same
US5359100A (en) * 1987-10-15 1994-10-25 Chiron Corporation Bifunctional blocked phosphoramidites useful in making nucleic acid mutimers
US5104791A (en) * 1988-02-09 1992-04-14 E. I. Du Pont De Nemours And Company Particle counting nucleic acid hybridization assays
CA2032203C (fr) * 1989-12-29 2009-05-19 Christine L. Brakel Essai de capture par amplification
US5147777A (en) * 1990-06-18 1992-09-15 Eastman Kodak Company Biologically active reagents prepared from carboxy-containing polymer, analytical element and methods of use
EP0466367B1 (fr) * 1990-06-28 1995-08-23 Wakunaga Seiyaku Kabushiki Kaisha Méthode pour la détection d'acides nucléiques
GB9019512D0 (en) * 1990-09-06 1990-10-24 Ici Plc Assay method
US6251581B1 (en) 1991-05-22 2001-06-26 Dade Behring Marburg Gmbh Assay method utilizing induced luminescence
US5578498A (en) 1991-05-22 1996-11-26 Behringwerke Ag Metal chelate containing compositions for use in chemiluminescent assays
JPH0538300A (ja) * 1991-08-07 1993-02-19 Hitachi Ltd 核酸の測定方法及び核酸測定用自動分析装置
FR2720508B1 (fr) * 1994-05-25 1996-08-09 Rech Developp Activ Commun Procédé de mise en évidence d'un analyte dans un échantillon et dispositif pour mettre en Óoeuvre le procédé.
US5747256A (en) * 1995-12-19 1998-05-05 Beckman Instruments, Inc. Homogeneous DNA probe titration assay
DE69637518D1 (de) * 1995-12-22 2008-06-19 Dade Behring Marburg Gmbh Homogene vervielfältigung und nachweis von nukleinsäuren
WO1999023258A1 (fr) * 1997-10-31 1999-05-14 Gen-Probe Incorporated Procedes de detection d'acide nucleique
US10465236B2 (en) 2013-12-23 2019-11-05 University Of Queensland Nucleic acid detection method and kit

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4713326A (en) * 1983-07-05 1987-12-15 Molecular Diagnostics, Inc. Coupling of nucleic acids to solid support by photochemical methods
CA1223222A (fr) * 1984-02-22 1987-06-23 Nanibhushan Dattagupta Sonde moleculaire contenant un acide nucleique immobilise
US4605686A (en) * 1984-03-13 1986-08-12 Sekisui Kagaku Kogyo Kabushiki Kaisha Latex for immunoserological tests and a method for the production of the same
JPS61501746A (ja) * 1984-04-05 1986-08-21 ライフ　テクノロジ−ズ，インコ−ポレイテツド 核酸の固定化法

Also Published As

Publication number Publication date
JPS63502875A (ja) 1988-10-27
WO1987005334A1 (fr) 1987-09-11
EP0259453A1 (fr) 1988-03-16

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