CA1265522C - - Google Patents

Info

Publication number
CA1265522C
CA1265522C CA 448829 CA448829A CA1265522C CA 1265522 C CA1265522 C CA 1265522C CA 448829 CA448829 CA 448829 CA 448829 A CA448829 A CA 448829A CA 1265522 C CA1265522 C CA 1265522C
Authority
CA
Canada
Prior art keywords
methyl
yield obtained
diastereomeric compounds
derivative
separated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA 448829
Other languages
English (en)
Other versions
CA1257599A (en
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to CA000576252A priority Critical patent/CA1265522A/en
Publication of CA1257599A publication Critical patent/CA1257599A/en
Application granted granted Critical
Publication of CA1265522C publication Critical patent/CA1265522C/xx
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CA000448829A 1983-03-07 1984-03-05 TRANS-3-[(4-METHOXYPHENOXY)-METHYL]-1-METHYL- 4-PHENYLPIPERIDINE Expired CA1257599A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA000576252A CA1265522A (en) 1983-03-07 1988-08-31 (+)-trans-3-¬(4-methoxyphenoxy)-methyl|-1- methyl-4-phenylperidine (+)-mandelate

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK111583A DK149624C (da) 1983-03-07 1983-03-07 Fremgangsmaade til fremstilling af (+)-trans-3-((4-methoxyphenoxy)-methyl)-1-methyl-4-phenylpiperidin eller et farmaceutisk acceptabelt salt heraf ud fra en blanding af enantiomererne

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA000576252A Division CA1265522A (en) 1983-03-07 1988-08-31 (+)-trans-3-¬(4-methoxyphenoxy)-methyl|-1- methyl-4-phenylperidine (+)-mandelate

Publications (2)

Publication Number Publication Date
CA1257599A CA1257599A (en) 1989-07-18
CA1265522C true CA1265522C (de) 1990-02-06

Family

ID=8101175

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000448829A Expired CA1257599A (en) 1983-03-07 1984-03-05 TRANS-3-[(4-METHOXYPHENOXY)-METHYL]-1-METHYL- 4-PHENYLPIPERIDINE

Country Status (12)

Country Link
US (1) US4571424A (de)
EP (1) EP0123832B1 (de)
JP (1) JPS6069065A (de)
AT (1) ATE30910T1 (de)
CA (1) CA1257599A (de)
DE (1) DE3467574D1 (de)
DK (1) DK149624C (de)
ES (1) ES8504710A1 (de)
FI (1) FI80261C (de)
GR (1) GR81929B (de)
IE (1) IE57002B1 (de)
NO (1) NO164594C (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE66332B1 (en) * 1986-11-03 1995-12-27 Novo Nordisk As Piperidine compounds and their preparation and use
US5254556A (en) * 1988-11-07 1993-10-19 Janssen Pharmaceutica N.V. 3-piperidinyl-1,2-benzisoxazoles
IL98757A (en) * 1990-07-18 1997-01-10 Novo Nordisk As Piperidine derivatives their preparation and pharmaceutical compositions containing them
CA2162400A1 (en) * 1993-05-28 1994-12-08 William M. Snyder Process for preparing and resolving 2-phenyl-3-aminopiperidine
US7470244B2 (en) * 1996-01-26 2008-12-30 Harrison Jr Shelton E Flexion-discouraging splint system, method and device
KR100828218B1 (ko) 2003-09-12 2008-05-07 화이자 인코포레이티드 알파-2-델타 리간드 및 세로토닌/노르아드레날린 재흡수 억제제를 포함하는 조합물
DE102005063192A1 (de) * 2005-12-30 2007-07-05 Basf Ag Racematspaltung von 2,6-trans-Dimethyl-morpholin

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1422263A (en) * 1973-01-30 1976-01-21 Ferrosan As 4-phenyl-piperidine compounds
US4442113A (en) * 1981-05-07 1984-04-10 A/S Ferrosan Long-term weight reduction of obese patients using femoxetine

Also Published As

Publication number Publication date
IE840496L (en) 1984-09-07
DK111583A (da) 1984-09-08
DK149624B (da) 1986-08-18
IE57002B1 (en) 1992-03-11
GR81929B (de) 1984-12-12
US4571424A (en) 1986-02-18
ES530355A0 (es) 1985-05-01
JPS6069065A (ja) 1985-04-19
ATE30910T1 (de) 1987-12-15
EP0123832A1 (de) 1984-11-07
FI80261B (fi) 1990-01-31
DE3467574D1 (en) 1987-12-23
EP0123832B1 (de) 1987-11-19
CA1257599A (en) 1989-07-18
ES8504710A1 (es) 1985-05-01
FI840872A (fi) 1984-09-08
NO164594C (no) 1990-10-24
FI840872A0 (fi) 1984-03-05
DK149624C (da) 1987-02-02
DK111583D0 (da) 1983-03-07
NO840847L (no) 1984-09-10
FI80261C (fi) 1990-05-10
NO164594B (no) 1990-07-16

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Legal Events

Date Code Title Description
MKEX Expiry