ES8707167A1 - Un procedimiento para producir treo-3-(3,4-metilendioxifenil) serina opticamente activa - Google Patents

Un procedimiento para producir treo-3-(3,4-metilendioxifenil) serina opticamente activa

Info

Publication number
ES8707167A1
ES8707167A1 ES555359A ES555359A ES8707167A1 ES 8707167 A1 ES8707167 A1 ES 8707167A1 ES 555359 A ES555359 A ES 555359A ES 555359 A ES555359 A ES 555359A ES 8707167 A1 ES8707167 A1 ES 8707167A1
Authority
ES
Spain
Prior art keywords
serine
optically active
methylenedioxyphenyl
threo
active threo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES555359A
Other languages
English (en)
Other versions
ES555359A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Pharmaceuticals Co Ltd
Original Assignee
Sumitomo Pharmaceuticals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Pharmaceuticals Co Ltd filed Critical Sumitomo Pharmaceuticals Co Ltd
Publication of ES555359A0 publication Critical patent/ES555359A0/es
Publication of ES8707167A1 publication Critical patent/ES8707167A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)

Abstract

PROCEDIMIENTO PARA PRODUCIR TREO-3-(3,4-METILENDIOXIFENIL)SERINA OPTICAMENTE ACTIVA. COMPRENDE: A) TRATAR A UNA MEZCLA D Y L-ISOMERA DE ESTER ALQUILICO DE TREO-3-(3,4-METILENDIOXIFENIL)SERINA DE FORMULA (II) CON ACIDO PIROGLUTAMICO OPTICAMENTE ACTIVO, ENTRE 0 Y 80JC Y EN ETANOL, PARA OBTENER UNA SAL DIASTEREOISOMERA INSOLUBLE; Y B) HACER REACCIONAR A LA SAL DIASTEREOISOMERA CON HIDROXIDO SODICO EN AGUA Y CON ENFRIAMIENTO, PARA OBTENER UN COMPUESTO DE FORMULA (I). SIENDO: R ALQUILO DE C 1 A 4.
ES555359A 1985-05-29 1986-05-27 Un procedimiento para producir treo-3-(3,4-metilendioxifenil) serina opticamente activa Expired ES8707167A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11558885 1985-05-29

Publications (2)

Publication Number Publication Date
ES555359A0 ES555359A0 (es) 1987-07-16
ES8707167A1 true ES8707167A1 (es) 1987-07-16

Family

ID=14666313

Family Applications (1)

Application Number Title Priority Date Filing Date
ES555359A Expired ES8707167A1 (es) 1985-05-29 1986-05-27 Un procedimiento para producir treo-3-(3,4-metilendioxifenil) serina opticamente activa

Country Status (3)

Country Link
EP (1) EP0204481A3 (es)
JP (1) JPS6259274A (es)
ES (1) ES8707167A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9808069D0 (en) * 1998-04-16 1998-06-17 Vanguard Medica Ltd Novel processes
WO2005021502A1 (ja) * 2003-08-29 2005-03-10 Takeda Pharmaceutical Company Limited 光学活性トレオ−β−アルキルトリプトファン誘導体の製造法およびその中間体
CN113816943B (zh) * 2017-12-25 2024-02-13 重庆圣华曦药业股份有限公司 屈昔多巴关键中间体的拆分方法
CN110467539B (zh) * 2019-08-30 2023-01-06 浙江普洛家园药业有限公司 一种2，6-二甲基酪氨酸酯的拆分方法及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3360726D1 (en) * 1982-01-14 1985-10-17 Sumitomo Chemical Co Process for producing threo-3-(3,4-dihydroxyphenyl)serine
CA1223602A (en) * 1983-05-25 1987-06-30 Naohito Ohashi Process for producing 3-(3,4-dihydroxyphenyl) serine

Also Published As

Publication number Publication date
ES555359A0 (es) 1987-07-16
EP0204481A2 (en) 1986-12-10
JPS6259274A (ja) 1987-03-14
EP0204481A3 (en) 1987-09-16

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