DK149624C - Fremgangsmaade til fremstilling af (+)-trans-3-((4-methoxyphenoxy)-methyl)-1-methyl-4-phenylpiperidin eller et farmaceutisk acceptabelt salt heraf ud fra en blanding af enantiomererne - Google Patents

Fremgangsmaade til fremstilling af (+)-trans-3-((4-methoxyphenoxy)-methyl)-1-methyl-4-phenylpiperidin eller et farmaceutisk acceptabelt salt heraf ud fra en blanding af enantiomererne

Info

Publication number
DK149624C
DK149624C DK111583A DK111583A DK149624C DK 149624 C DK149624 C DK 149624C DK 111583 A DK111583 A DK 111583A DK 111583 A DK111583 A DK 111583A DK 149624 C DK149624 C DK 149624C
Authority
DK
Denmark
Prior art keywords
methyl
phenylpiperidine
methoxyphenoxy
trans
mixture
Prior art date
Application number
DK111583A
Other languages
English (en)
Other versions
DK149624B (da
DK111583A (da
DK111583D0 (da
Inventor
Jaergen Anders Christensen
Peer Everland
Original Assignee
Ferrosan As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrosan As filed Critical Ferrosan As
Publication of DK111583D0 publication Critical patent/DK111583D0/da
Priority to DK111583A priority Critical patent/DK149624C/da
Priority to US06/584,721 priority patent/US4571424A/en
Priority to IE496/84A priority patent/IE57002B1/en
Priority to CA000448829A priority patent/CA1257599A/en
Priority to FI840872A priority patent/FI80261C/fi
Priority to NO840847A priority patent/NO164594C/no
Priority to JP59042208A priority patent/JPS6069065A/ja
Priority to EP84102439A priority patent/EP0123832B1/en
Priority to DE8484102439T priority patent/DE3467574D1/de
Priority to AT84102439T priority patent/ATE30910T1/de
Priority to ES530355A priority patent/ES530355A0/es
Priority to GR74014A priority patent/GR81929B/el
Publication of DK111583A publication Critical patent/DK111583A/da
Publication of DK149624B publication Critical patent/DK149624B/da
Application granted granted Critical
Publication of DK149624C publication Critical patent/DK149624C/da
Priority to CA000576252A priority patent/CA1265522A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK111583A 1983-03-07 1983-03-07 Fremgangsmaade til fremstilling af (+)-trans-3-((4-methoxyphenoxy)-methyl)-1-methyl-4-phenylpiperidin eller et farmaceutisk acceptabelt salt heraf ud fra en blanding af enantiomererne DK149624C (da)

Priority Applications (13)

Application Number Priority Date Filing Date Title
DK111583A DK149624C (da) 1983-03-07 1983-03-07 Fremgangsmaade til fremstilling af (+)-trans-3-((4-methoxyphenoxy)-methyl)-1-methyl-4-phenylpiperidin eller et farmaceutisk acceptabelt salt heraf ud fra en blanding af enantiomererne
US06/584,721 US4571424A (en) 1983-03-07 1984-02-29 Optical resolution of racemic femoxetine
IE496/84A IE57002B1 (en) 1983-03-07 1984-03-01 Process for the optical resolution of a mixture of the enantiomers of trans-3-((4-methoxyphenoxy)-methyl)-1-methyl-4-phenylpiperidine
CA000448829A CA1257599A (en) 1983-03-07 1984-03-05 TRANS-3-[(4-METHOXYPHENOXY)-METHYL]-1-METHYL- 4-PHENYLPIPERIDINE
FI840872A FI80261C (fi) 1983-03-07 1984-03-05 Foerfarande foer optisk upploesning av en blandning av enantiomerer av trans-3-/(4-metoxifenoxi)-metyl/-1-metyl-4- fenylpiperidin.
NO840847A NO164594C (no) 1983-03-07 1984-03-06 Fremgangsmaate for fremstilling av (+)-trans-3-((4-metoksyfenoksy)-metyl)-1-metyl-4-fenylpiperidin eller et farmasoeytisk salt derav fra en blanding av enantiomerene.
JP59042208A JPS6069065A (ja) 1983-03-07 1984-03-07 ラセミ化トランス―３―［（４―メトキシフェノキシ）―メチル］―１―メチル―４―フェニルピペリジンの光学的分割方法
EP84102439A EP0123832B1 (en) 1983-03-07 1984-03-07 Process for the optical resolution of a mixture of the enantiomers of trans-3-((4-methoxyphenoxy)-methyl)-1-methyl-4-phenylpiperidine
DE8484102439T DE3467574D1 (en) 1983-03-07 1984-03-07 Process for the optical resolution of a mixture of the enantiomers of trans-3-((4-methoxyphenoxy)-methyl)-1-methyl-4-phenylpiperidine
AT84102439T ATE30910T1 (de) 1983-03-07 1984-03-07 Verfahren zur optischen trennung einer enantiomer-mischung von trans-3-((4-methoxyphenoxy)-methyl)1-methyl-4-phenyl-piperidin.
ES530355A ES530355A0 (es) 1983-03-07 1984-03-07 Procedimiento para la resolucion optica de una mezcla de enantiomeros de un derivados de piperidina.
GR74014A GR81929B (da) 1983-03-07 1984-03-07
CA000576252A CA1265522A (en) 1983-03-07 1988-08-31 (+)-trans-3-¬(4-methoxyphenoxy)-methyl|-1- methyl-4-phenylperidine (+)-mandelate

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK111583A DK149624C (da) 1983-03-07 1983-03-07 Fremgangsmaade til fremstilling af (+)-trans-3-((4-methoxyphenoxy)-methyl)-1-methyl-4-phenylpiperidin eller et farmaceutisk acceptabelt salt heraf ud fra en blanding af enantiomererne
DK111583 1983-03-07

Publications (4)

Publication Number Publication Date
DK111583D0 DK111583D0 (da) 1983-03-07
DK111583A DK111583A (da) 1984-09-08
DK149624B DK149624B (da) 1986-08-18
DK149624C true DK149624C (da) 1987-02-02

Family

ID=8101175

Family Applications (1)

Application Number Title Priority Date Filing Date
DK111583A DK149624C (da) 1983-03-07 1983-03-07 Fremgangsmaade til fremstilling af (+)-trans-3-((4-methoxyphenoxy)-methyl)-1-methyl-4-phenylpiperidin eller et farmaceutisk acceptabelt salt heraf ud fra en blanding af enantiomererne

Country Status (12)

Country Link
US (1) US4571424A (da)
EP (1) EP0123832B1 (da)
JP (1) JPS6069065A (da)
AT (1) ATE30910T1 (da)
CA (1) CA1257599A (da)
DE (1) DE3467574D1 (da)
DK (1) DK149624C (da)
ES (1) ES530355A0 (da)
FI (1) FI80261C (da)
GR (1) GR81929B (da)
IE (1) IE57002B1 (da)
NO (1) NO164594C (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE66332B1 (en) * 1986-11-03 1995-12-27 Novo Nordisk As Piperidine compounds and their preparation and use
US5254556A (en) * 1988-11-07 1993-10-19 Janssen Pharmaceutica N.V. 3-piperidinyl-1,2-benzisoxazoles
IL98757A (en) * 1990-07-18 1997-01-10 Novo Nordisk As Piperidine derivatives their preparation and pharmaceutical compositions containing them
JPH08507297A (ja) * 1993-05-28 1996-08-06 ファイザー・インク． ２−フェニル−３−アミノピペリジンを調製および分割する方法
US7470244B2 (en) * 1996-01-26 2008-12-30 Harrison Jr Shelton E Flexion-discouraging splint system, method and device
NZ545494A (en) 2003-09-12 2009-10-30 Pfizer Combinations comprising alpha-2-delta ligands and serotonin / noradrenaline re-uptake inhibitors
DE102005063192A1 (de) * 2005-12-30 2007-07-05 Basf Ag Racematspaltung von 2,6-trans-Dimethyl-morpholin

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1422263A (en) * 1973-01-30 1976-01-21 Ferrosan As 4-phenyl-piperidine compounds
US4442113A (en) * 1981-05-07 1984-04-10 A/S Ferrosan Long-term weight reduction of obese patients using femoxetine

Also Published As

Publication number Publication date
NO164594C (no) 1990-10-24
CA1257599A (en) 1989-07-18
FI80261B (fi) 1990-01-31
DE3467574D1 (en) 1987-12-23
NO840847L (no) 1984-09-10
ATE30910T1 (de) 1987-12-15
ES8504710A1 (es) 1985-05-01
DK149624B (da) 1986-08-18
IE57002B1 (en) 1992-03-11
DK111583A (da) 1984-09-08
ES530355A0 (es) 1985-05-01
FI80261C (fi) 1990-05-10
EP0123832B1 (en) 1987-11-19
CA1265522C (da) 1990-02-06
EP0123832A1 (en) 1984-11-07
US4571424A (en) 1986-02-18
NO164594B (no) 1990-07-16
DK111583D0 (da) 1983-03-07
FI840872A (fi) 1984-09-08
FI840872A0 (fi) 1984-03-05
IE840496L (en) 1984-09-07
GR81929B (da) 1984-12-12
JPS6069065A (ja) 1985-04-19

Similar Documents

Publication Publication Date Title
FR2623498B1 (fr) Nouveaux composes enantiomeres derives d'amino-acides, leur procede de preparation et leurs applications therapeutiques
HUT59376A (en) Process for producing r(+)-n-propargyl-1-aminoindane and pharmaceutical compositions comprising such compound
KR920012035A (ko) 치환된 피리딜-디하이드록시-헵텐 산 및 그의 염
DE3752362D1 (de) Optisch aktive Verbindungen
DK149624C (da) Fremgangsmaade til fremstilling af (+)-trans-3-((4-methoxyphenoxy)-methyl)-1-methyl-4-phenylpiperidin eller et farmaceutisk acceptabelt salt heraf ud fra en blanding af enantiomererne
FI117438B (fi) Menetelmä optisesti rikastetun bupivakaiinin valmistamiseksi
KR920701177A (ko) 3-아릴옥사졸리디논 유도체, 그의 제조 방법 및 그의 치료 용도
KR0147834B1 (ko) (+-)-시스 또는 (+-)-트란스-퍼메트르산의 광학 분할법
FR2405922A1 (fr) Esters et thiolesters d'acides amines, procede d'obtention et application a titre de pesticides
FR2354764A1 (fr) Nouveaux ethers cycliques derives de l'acide prostanoique et leur procede de preparation
IE900584L (en) A process for preparation of enantiomerically pure¹polysubstituted 1,4-dihydropyridines
ATE118476T1 (de) Verfahren zur herstellung von l-carnitin aus d,l- carnitinnitrilsalzen.
DE3061367D1 (en) Process for the obtention of the enantiomeric forms of 4-cyane-1-(n-methyl-n-(2'-((3",4"-dimethoxyphenyl))ethyl-amino)-5-methyl-4-(3',4',5'-trimethoxyphenyl) hexane and its salts
KR880003960A (ko) 도파민작용제로서의 헤테로[f] 융합 탄소환 피리딘류
SE8102525L (sv) Forfarande for framstellning av cyklopropankarboxylsyraester-derivat
IE47236B1 (en) Optical resolution of amino acids into optical antipodes
ATE45945T1 (de) S(-)-celiprolol, dessen pharmazeutisch vertraegliche salze, verfahren zu deren herstellung und pharmazeutische zubereitung.
ATE42203T1 (de) Semi-synthetisches verfahren zur herstellung von insulin.
KR880011096A (ko) 광학 활성 옥소-이소인돌리닐 유도체
ES2003994A6 (es) Procedimiento de preparacion de nuevas 2-cloro-12-(3-dimetilamino-2-metilpropil)-12h-dibenzo(d,g) (i,3,6) dioxazocinas opticamente activas y de sus sales de adicion acidas farmaceuticamente aceptables
DE69020377D1 (de) Verfahren zur Herstellung von für die Umwelt unbedenklichem Dicofol und dessen Formulierungen.
EP0139265A2 (en) Imidazolidine prostaglandins
SU520361A1 (ru) Способ получени алкиловых эфиров 2-бензимидазолилкарбаминовой кислоты
KR940003937A (ko) 신규한 이소부틸-치환 메탄술포닐 퀴놀릴메톡시페닐-시클로알킬아세트아미드
ATE11530T1 (de) P-chlorophenoxyessigsaeure-derivat, verfahren zu dessen herstellung und pharmazeutische zusammenstellung.

Legal Events

Date Code Title Description
PBP Patent lapsed