CA1264207A - Collagen synthetic vascular graft composite - Google Patents
Collagen synthetic vascular graft compositeInfo
- Publication number
- CA1264207A CA1264207A CA000473089A CA473089A CA1264207A CA 1264207 A CA1264207 A CA 1264207A CA 000473089 A CA000473089 A CA 000473089A CA 473089 A CA473089 A CA 473089A CA 1264207 A CA1264207 A CA 1264207A
- Authority
- CA
- Canada
- Prior art keywords
- collagen
- graft
- substrate
- vascular graft
- plasticizer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229920001436 collagen Polymers 0.000 title claims abstract description 85
- 102000008186 Collagen Human genes 0.000 title claims abstract description 84
- 108010035532 Collagen Proteins 0.000 title claims abstract description 84
- 230000002792 vascular Effects 0.000 title claims abstract description 46
- 239000002131 composite material Substances 0.000 title description 2
- 239000000758 substrate Substances 0.000 claims abstract description 35
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 claims abstract description 27
- 239000004014 plasticizer Substances 0.000 claims abstract description 22
- 239000002002 slurry Substances 0.000 claims abstract description 21
- 238000000034 method Methods 0.000 claims abstract description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 23
- 239000005020 polyethylene terephthalate Substances 0.000 claims description 20
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical group OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 11
- 241000283690 Bos taurus Species 0.000 claims description 9
- 239000000463 material Substances 0.000 claims description 7
- 235000011187 glycerol Nutrition 0.000 claims description 5
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 4
- 238000001035 drying Methods 0.000 claims description 4
- -1 polyethylene terephthalate Polymers 0.000 claims description 4
- 239000008213 purified water Substances 0.000 claims description 4
- 239000000600 sorbitol Substances 0.000 claims description 4
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical group OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 3
- 229920000139 polyethylene terephthalate Polymers 0.000 claims description 3
- 239000011248 coating agent Substances 0.000 claims description 2
- 238000000576 coating method Methods 0.000 claims description 2
- 238000004132 cross linking Methods 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 229920002994 synthetic fiber Polymers 0.000 claims description 2
- 238000000184 acid digestion Methods 0.000 claims 1
- 238000009877 rendering Methods 0.000 claims 1
- 239000012209 synthetic fiber Substances 0.000 claims 1
- 238000001291 vacuum drying Methods 0.000 claims 1
- 238000011282 treatment Methods 0.000 abstract description 9
- 238000009940 knitting Methods 0.000 abstract description 2
- 238000009941 weaving Methods 0.000 abstract description 2
- 239000008280 blood Substances 0.000 description 22
- 210000004369 blood Anatomy 0.000 description 22
- 229920004934 Dacron® Polymers 0.000 description 17
- 208000007536 Thrombosis Diseases 0.000 description 12
- 210000001519 tissue Anatomy 0.000 description 9
- 230000035602 clotting Effects 0.000 description 8
- 206010053567 Coagulopathies Diseases 0.000 description 7
- 239000007943 implant Substances 0.000 description 7
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 6
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
- 239000004744 fabric Substances 0.000 description 6
- 230000015572 biosynthetic process Effects 0.000 description 5
- 230000002829 reductive effect Effects 0.000 description 5
- 208000032843 Hemorrhage Diseases 0.000 description 4
- 238000003780 insertion Methods 0.000 description 4
- 230000037431 insertion Effects 0.000 description 4
- 239000011159 matrix material Substances 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- 230000000740 bleeding effect Effects 0.000 description 3
- 230000017531 blood circulation Effects 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 239000006185 dispersion Substances 0.000 description 3
- 239000012153 distilled water Substances 0.000 description 3
- 238000000338 in vitro Methods 0.000 description 3
- 239000008399 tap water Substances 0.000 description 3
- 235000020679 tap water Nutrition 0.000 description 3
- 102000009123 Fibrin Human genes 0.000 description 2
- 108010073385 Fibrin Proteins 0.000 description 2
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- 244000309466 calf Species 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 229950003499 fibrin Drugs 0.000 description 2
- 238000002513 implantation Methods 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 230000000670 limiting effect Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000036961 partial effect Effects 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 210000002435 tendon Anatomy 0.000 description 2
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 239000004809 Teflon Substances 0.000 description 1
- 229920006362 Teflon® Polymers 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 230000003466 anti-cipated effect Effects 0.000 description 1
- 230000023555 blood coagulation Effects 0.000 description 1
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 description 1
- 239000000920 calcium hydroxide Substances 0.000 description 1
- 229910001861 calcium hydroxide Inorganic materials 0.000 description 1
- 235000011116 calcium hydroxide Nutrition 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 238000001976 enzyme digestion Methods 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000003754 fetus Anatomy 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 210000002950 fibroblast Anatomy 0.000 description 1
- 230000003176 fibrotic effect Effects 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 229960002897 heparin Drugs 0.000 description 1
- 229920000669 heparin Polymers 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 239000010985 leather Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 230000020477 pH reduction Effects 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 230000037368 penetrate the skin Effects 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000036647 reaction Effects 0.000 description 1
- 210000000329 smooth muscle myocyte Anatomy 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/507—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/502—Plasticizers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2002/065—Y-shaped blood vessels
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Vascular Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57508284A | 1984-01-30 | 1984-01-30 | |
| US575,082 | 1990-08-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1264207A true CA1264207A (en) | 1990-01-09 |
Family
ID=24298858
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000473089A Expired CA1264207A (en) | 1984-01-30 | 1985-01-29 | Collagen synthetic vascular graft composite |
Country Status (11)
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6229532A (ja) * | 1985-07-31 | 1987-02-07 | Koken:Kk | 抗血栓性医用材料及びその製造方法 |
| JPS6238172A (ja) * | 1985-08-12 | 1987-02-19 | 株式会社 高研 | 抗血栓性医用材料の製造方法 |
| DE3608158A1 (de) * | 1986-03-12 | 1987-09-17 | Braun Melsungen Ag | Mit vernetzter gelatine impraegnierte gefaessprothese und verfahren zu ihrer herstellung |
| US5298255A (en) * | 1988-10-28 | 1994-03-29 | Terumo Kabushiki Kaisha | Antithrombic medical material, artificial internal organ, and method for production of antithrombic medical material |
| ES2076970T3 (es) * | 1988-10-28 | 1995-11-16 | Terumo Corp | Material medico antitrombotico, organo interno artificial y metodo para la produccion de material medico antitrombotico. |
| DE3913926A1 (de) * | 1989-04-27 | 1990-10-31 | Heinz Helmut Dr Med Werner | Textile gefaessprothese |
| US5292362A (en) * | 1990-07-27 | 1994-03-08 | The Trustees Of Columbia University In The City Of New York | Tissue bonding and sealing composition and method of using the same |
| US5282847A (en) * | 1991-02-28 | 1994-02-01 | Medtronic, Inc. | Prosthetic vascular grafts with a pleated structure |
| CA2188563C (en) * | 1994-04-29 | 2005-08-02 | Andrew W. Buirge | Stent with collagen |
| US5665114A (en) * | 1994-08-12 | 1997-09-09 | Meadox Medicals, Inc. | Tubular expanded polytetrafluoroethylene implantable prostheses |
| TW510803B (en) * | 1996-11-20 | 2002-11-21 | Yasuhiko Shimizu | Man-made esophagus and its manufacturing method |
| US7241309B2 (en) | 1999-04-15 | 2007-07-10 | Scimed Life Systems, Inc. | Self-aggregating protein compositions and use as sealants |
| US6177609B1 (en) | 1997-03-10 | 2001-01-23 | Meadox Medicals, Inc. | Self-aggregating protein compositions and use as sealants |
| US6129757A (en) | 1998-05-18 | 2000-10-10 | Scimed Life Systems | Implantable members for receiving therapeutically useful compositions |
| US6863696B2 (en) | 2000-02-16 | 2005-03-08 | Viktoria Kantsevitcha | Vascular prosthesis |
| LV12702B (lv) * | 2000-02-16 | 2001-10-20 | Viktorija Kancevica | Arteriju proteze |
| US20120029655A1 (en) * | 2009-04-08 | 2012-02-02 | International Centre For Cardio Thoracic And Vascular Diseases | Implantable xenograft prepared from a non-human tissue portion |
| DE102009037134A1 (de) | 2009-07-31 | 2011-02-03 | Aesculap Ag | Tubuläres Implantat zum Ersatz von natürlichen Blutgefäßen |
| US9572907B2 (en) | 2010-10-01 | 2017-02-21 | Covidien Lp | Implantable polymeric films |
| WO2017053433A1 (en) | 2015-09-21 | 2017-03-30 | Modern Meadow, Inc. | Fiber reinforced tissue composites |
| US10519285B2 (en) * | 2016-02-15 | 2019-12-31 | Modern Meadow, Inc. | Method for biofabricating composite material |
| AU2018253595A1 (en) | 2017-11-13 | 2019-05-30 | Modern Meadow, Inc. | Biofabricated leather articles having zonal properties |
| US11352497B2 (en) | 2019-01-17 | 2022-06-07 | Modern Meadow, Inc. | Layered collagen materials and methods of making the same |
| CN118542977B (zh) * | 2024-05-30 | 2024-11-08 | 山东黄河三角洲纺织科技研究院有限公司 | 一种编织型人造血管的涂层方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1185332B (de) * | 1961-03-01 | 1965-01-14 | Ethicon Inc | Chirurgische Prothese |
| DE1494939B2 (de) * | 1963-06-11 | 1972-03-02 | Buddecke, Eckhart, Prof Dr , 4400 Munster | Implantationsmatenal fur Prothesen zum Ersatz von Arterien und anderen Korper safte enthaltenden Bahnen und Hohlorganen und Verfahren zu dessen Herstellung |
| CH472219A (de) * | 1963-06-15 | 1969-05-15 | Spofa Vereinigte Pharma Werke | Hochporöse Kollagen-Gewebe-Blutgefässprothese und Verfahren zur Herstellung derselben |
| US3272204A (en) * | 1965-09-22 | 1966-09-13 | Ethicon Inc | Absorbable collagen prosthetic implant with non-absorbable reinforcing strands |
| US3479670A (en) | 1966-10-19 | 1969-11-25 | Ethicon Inc | Tubular prosthetic implant having helical thermoplastic wrapping therearound |
| DE1566358B2 (de) * | 1967-03-09 | 1977-04-21 | Meadox Medicals, Inc., Haiedon, NJ. (V.StA.) | Gefaessprothese fuer chirurgische zwecke |
| US3928653A (en) | 1975-02-05 | 1975-12-23 | Tee Pak Inc | Collagen slurry containing partial fatty acid esters of glycerin |
| DE2843963A1 (de) * | 1978-10-09 | 1980-04-24 | Merck Patent Gmbh | Im koerper resorbierbare geformte masse auf basis von kollagen und ihre verwendung in der medizin |
| SU904693A1 (ru) * | 1980-05-12 | 1982-02-15 | Первый Московский Ордена Ленина И Ордена Трудового Красного Знамени Медицинский Институт Им. И.М.Сеченова | Протез сосуда |
| US4416028A (en) | 1981-01-22 | 1983-11-22 | Ingvar Eriksson | Blood vessel prosthesis |
| US4409172A (en) * | 1981-02-13 | 1983-10-11 | Thoratec Laboratories Corporation | Device and method for fabricating multi-layer tubing using a freely suspended mandrel |
| US4546500A (en) * | 1981-05-08 | 1985-10-15 | Massachusetts Institute Of Technology | Fabrication of living blood vessels and glandular tissues |
| WO1983003536A1 (en) * | 1982-04-19 | 1983-10-27 | Massachusetts Inst Technology | A multilayer bioreplaceable blood vessel prosthesis |
-
1985
- 1985-01-28 IL IL74179A patent/IL74179A/xx not_active IP Right Cessation
- 1985-01-29 CA CA000473089A patent/CA1264207A/en not_active Expired
- 1985-01-29 GB GB08502157A patent/GB2153685B/en not_active Expired
- 1985-01-29 FR FR858501218A patent/FR2558719B1/fr not_active Expired
- 1985-01-29 NL NL8500240A patent/NL193264C/nl not_active IP Right Cessation
- 1985-01-30 JP JP60014592A patent/JPH0636818B2/ja not_active Expired - Lifetime
- 1985-01-30 DE DE19853503127 patent/DE3503127A1/de not_active Withdrawn
- 1985-01-30 CH CH410/85A patent/CH670379A5/de not_active IP Right Cessation
- 1985-01-30 AU AU38195/85A patent/AU577826B2/en not_active Expired
- 1985-01-30 SE SE8500421A patent/SE464058B/sv not_active IP Right Cessation
- 1985-01-30 BE BE0/214419A patent/BE901610A/fr unknown
-
1987
- 1987-04-13 GB GB08708757A patent/GB2187463B/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| SE464058B (sv) | 1991-03-04 |
| FR2558719A1 (fr) | 1985-08-02 |
| BE901610A (fr) | 1985-05-17 |
| DE3503127A1 (de) | 1985-08-01 |
| NL193264B (nl) | 1999-01-04 |
| JPH0636818B2 (ja) | 1994-05-18 |
| GB2187463A (en) | 1987-09-09 |
| SE8500421L (sv) | 1985-09-02 |
| GB2187463B (en) | 1988-12-14 |
| GB2153685B (en) | 1988-12-14 |
| IL74179A (en) | 1992-05-25 |
| JPS60203264A (ja) | 1985-10-14 |
| NL193264C (nl) | 1999-05-06 |
| GB8708757D0 (en) | 1987-05-20 |
| IL74179A0 (en) | 1985-04-30 |
| CH670379A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1989-06-15 |
| AU3819585A (en) | 1985-08-08 |
| NL8500240A (nl) | 1985-08-16 |
| AU577826B2 (en) | 1988-10-06 |
| SE8500421D0 (sv) | 1985-01-30 |
| GB2153685A (en) | 1985-08-29 |
| FR2558719B1 (fr) | 1989-10-20 |
| GB8502157D0 (en) | 1985-02-27 |
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