CA1253097A - Antibiotic x-14934a - Google Patents

Antibiotic x-14934a

Info

Publication number
CA1253097A
CA1253097A CA000459712A CA459712A CA1253097A CA 1253097 A CA1253097 A CA 1253097A CA 000459712 A CA000459712 A CA 000459712A CA 459712 A CA459712 A CA 459712A CA 1253097 A CA1253097 A CA 1253097A
Authority
CA
Canada
Prior art keywords
compound
formula
salt
antibiotic
feed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000459712A
Other languages
English (en)
French (fr)
Inventor
Chao-Min Liu
John Westley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of CA1253097A publication Critical patent/CA1253097A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/46—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin
    • C12P19/54—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin the cyclohexyl radical being bound directly to a nitrogen atom of two or more radicals, e.g. streptomycin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/445—The saccharide radical is condensed with a heterocyclic radical, e.g. everninomycin, papulacandin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces
    • C12R2001/55—Streptomyces hygroscopicus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Fodder In General (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Measurement Of Velocity Or Position Using Acoustic Or Ultrasonic Waves (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA000459712A 1983-07-28 1984-07-26 Antibiotic x-14934a Expired CA1253097A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/518,233 US4510317A (en) 1983-07-28 1983-07-28 Antibiotic X-14934A
US518,233 1983-07-28

Publications (1)

Publication Number Publication Date
CA1253097A true CA1253097A (en) 1989-04-25

Family

ID=24063126

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000459712A Expired CA1253097A (en) 1983-07-28 1984-07-26 Antibiotic x-14934a

Country Status (21)

Country Link
US (1) US4510317A (https=)
EP (1) EP0133971B1 (https=)
JP (1) JPS6051198A (https=)
KR (1) KR910005629B1 (https=)
AT (1) ATE33390T1 (https=)
AU (1) AU575574B2 (https=)
CA (1) CA1253097A (https=)
DE (1) DE3470313D1 (https=)
DK (1) DK159452C (https=)
ES (1) ES534644A0 (https=)
FI (1) FI76836C (https=)
GR (1) GR82437B (https=)
HU (1) HU193017B (https=)
IE (1) IE57274B1 (https=)
IL (1) IL72517A (https=)
MC (1) MC1615A1 (https=)
NO (1) NO158881C (https=)
NZ (1) NZ209022A (https=)
PH (1) PH20120A (https=)
PT (1) PT78991B (https=)
ZA (1) ZA845601B (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4707493A (en) * 1983-02-15 1987-11-17 Pfizer Inc. 19-epi-dianemycin as an anticoccidial and antibacterial agent
US4591559A (en) * 1983-07-28 1986-05-27 Hoffmann-La Roche Inc. Antibiotic X-14934A and a method for its preparation
US4625041A (en) * 1984-02-17 1986-11-25 Pfizer Inc. Acidic polycyclic ether antibiotic
US4894366A (en) * 1984-12-03 1990-01-16 Fujisawa Pharmaceutical Company, Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
DE3677844D1 (de) * 1985-05-28 1991-04-11 Lilly Co Eli Polyether-antibiotikum und verfahren zu seiner herstellung.
US5888788A (en) * 1994-05-18 1999-03-30 Union Nationale Des Groupements De Distillateurs D'alcool (Ungda) Use of ionophoretic polyether antibiotics for controlling bacterial growth in alcoholic fermentation
TW393413B (en) * 1996-01-19 2000-06-11 Shimano Kk Clipless bicycle pedal with large shoe-contacting area
EP2825178A4 (en) * 2012-03-16 2015-10-14 Univ Georgia Glycomimetics to inhibit pathogen-host interactions

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3953474A (en) * 1974-11-15 1976-04-27 Eli Lilly And Company Antibiotic A204I derivatives
GB2024806B (en) * 1978-03-16 1982-05-06 Taisho Pharmaceutical Co Ltd Onomycin derivatives
JPS5592387A (en) * 1978-12-29 1980-07-12 Taisho Pharmaceut Co Ltd Antibiotic substance tm-531
FR2463144A1 (fr) * 1979-08-13 1981-02-20 Syntex Inc Nouveaux diesters de laidlomycine, leur procede de production, compositions a usage veterinaire les contenant et leur utilisation pour accroitre le rendement d'assimilation des aliments chez un ruminant
US4431665A (en) * 1979-08-13 1984-02-14 Syntex (U.S.A.) Inc. Acylated laidlomycin derivatives
US4359583A (en) * 1980-09-16 1982-11-16 Taisho Pharmaceutical Co., Ltd. Antibiotics TM-531 B and TM-531 C
US4361649A (en) * 1981-07-20 1982-11-30 Pfizer Inc. Polycyclic ether antibiotic
GB2113671A (en) * 1982-01-19 1983-08-10 Pfizer Ltd Polycyclic ether antibiotics
GT198400008A (es) * 1983-02-15 1985-07-12 19-epi-dianemicina y procedimiento para el mismo
US4552843A (en) * 1984-02-17 1985-11-12 Pfizer Inc. Process for producing an acidic polycyclic ether antibiotic by cultivation of a novel strain of Streptomyces endus subspecies aureus

Also Published As

Publication number Publication date
EP0133971B1 (de) 1988-04-06
DK366084D0 (da) 1984-07-26
MC1615A1 (fr) 1985-07-18
DE3470313D1 (en) 1988-05-11
JPS6051198A (ja) 1985-03-22
KR850001291A (ko) 1985-03-18
FI843009L (fi) 1985-01-29
US4510317A (en) 1985-04-09
IE841949L (en) 1985-01-28
NZ209022A (en) 1987-08-31
KR910005629B1 (ko) 1991-08-01
IL72517A (en) 1988-03-31
ZA845601B (en) 1985-03-27
HU193017B (en) 1987-08-28
HUT36178A (en) 1985-08-28
IL72517A0 (en) 1984-11-30
FI843009A0 (fi) 1984-07-27
IE57274B1 (en) 1992-07-01
AU3124684A (en) 1985-01-31
AU575574B2 (en) 1988-08-04
DK159452B (da) 1990-10-15
EP0133971A1 (de) 1985-03-13
ATE33390T1 (de) 1988-04-15
DK159452C (da) 1991-03-18
ES8600640A1 (es) 1985-10-16
NO843054L (no) 1985-01-29
PT78991A (en) 1984-08-01
NO158881C (no) 1988-11-09
PH20120A (en) 1986-10-02
DK366084A (da) 1985-01-29
GR82437B (https=) 1984-12-13
PT78991B (en) 1986-10-23
FI76836B (fi) 1988-08-31
ES534644A0 (es) 1985-10-16
NO158881B (no) 1988-08-01
FI76836C (fi) 1988-12-12

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Legal Events

Date Code Title Description
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