CA1233177A - 2-mercaptopyrimidohexahydroquinolines et composes apparentes - Google Patents

2-mercaptopyrimidohexahydroquinolines et composes apparentes

Info

Publication number
CA1233177A
CA1233177A CA000463536A CA463536A CA1233177A CA 1233177 A CA1233177 A CA 1233177A CA 000463536 A CA000463536 A CA 000463536A CA 463536 A CA463536 A CA 463536A CA 1233177 A CA1233177 A CA 1233177A
Authority
CA
Canada
Prior art keywords
trans
formula
propyl
quinoline
octahydropyrimido
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000463536A
Other languages
English (en)
Inventor
Edmund C. Kornfeld
Cynthia L. Nichols
John M. Schaus
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of CA1233177A publication Critical patent/CA1233177A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CA000463536A 1983-09-26 1984-09-19 2-mercaptopyrimidohexahydroquinolines et composes apparentes Expired CA1233177A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US535,518 1983-09-26
US06/535,518 US4507478A (en) 1983-09-26 1983-09-26 2-Mercaptopyrimidohexahydroquinolines and related compounds

Publications (1)

Publication Number Publication Date
CA1233177A true CA1233177A (fr) 1988-02-23

Family

ID=24134587

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000463536A Expired CA1233177A (fr) 1983-09-26 1984-09-19 2-mercaptopyrimidohexahydroquinolines et composes apparentes

Country Status (12)

Country Link
US (1) US4507478A (fr)
EP (1) EP0138417B1 (fr)
JP (2) JPS60100580A (fr)
KR (1) KR870001160B1 (fr)
CA (1) CA1233177A (fr)
DE (1) DE3481615D1 (fr)
DK (1) DK451284A (fr)
GB (1) GB2146993B (fr)
GR (1) GR80411B (fr)
HU (1) HU193721B (fr)
IE (1) IE58095B1 (fr)
IL (1) IL73002A (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4599339A (en) * 1983-09-26 1986-07-08 Eli Lilly And Company Use of pyrimido[4,5-g]quinolines in treating parkinsonism
IL72730A (en) * 1983-09-26 1987-10-30 Lilly Co Eli Octahydro-2-pyrimido(4,5-g)quinolinamines,their preparation and pharmaceutical compositions containing them
US4764609A (en) * 1986-03-31 1988-08-16 Eli Lilly And Company Synthesis of 2-aminopyrimido[4,5-g]quinolines
US4826986A (en) * 1986-06-16 1989-05-02 Eli Lilly And Company 6-Oxo-trans-octa- and decahydroquinolines
US5134143A (en) * 1986-06-16 1992-07-28 Eli Lilly And Company BCD tricyclic ergoline part-structure analogues
US4762843A (en) * 1986-09-15 1988-08-09 Warner-Lambert Company Hetero [f] fused carbocyclic pyridines as dopaminergic agents
US5416090A (en) * 1991-01-31 1995-05-16 Eli Lilly And Company Method of treating inflammation
DE4228455A1 (de) * 1992-08-26 1994-09-15 Beiersdorf Ag Kosmetische und dermatologische Lichtschutzformulierungen mit einem Gehalt an Thiolen und/oder Thiolderivaten
DE4242328C2 (de) * 1992-12-15 1995-06-08 Alfred Dipl Ing Dr Freissmuth Mittel zur Entschwefelung, Entphosphorung, Entsilicierung und Entstickung von Roheisen- und Gußeisenschmelzen

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2794020A (en) * 1953-08-03 1957-05-28 Monsanto Chemicals 6-amino substituted 1, 2, 3, 4-tetrahydroquinolines
BE582178A (fr) * 1958-09-02
US4198415A (en) * 1979-01-22 1980-04-15 Eli Lilly And Company Prolactin inhibiting octahydro pyrazolo[3,4-g]quinolines
JPS59177383A (ja) * 1983-03-25 1984-10-08 Mitsui Eng & Shipbuild Co Ltd ステンレス鋼の応力腐食割れ防止構造
JPS63289902A (ja) * 1987-05-22 1988-11-28 Omron Tateisi Electronics Co 可変抵抗器

Also Published As

Publication number Publication date
JPH068291B2 (ja) 1994-02-02
US4507478A (en) 1985-03-26
IL73002A0 (en) 1984-12-31
IL73002A (en) 1987-09-16
HU193721B (en) 1987-11-30
HUT35263A (en) 1985-06-28
GB2146993B (en) 1987-07-08
EP0138417A3 (en) 1986-02-19
KR870001160B1 (ko) 1987-06-13
GB8423850D0 (en) 1984-10-24
JPH0528718B2 (fr) 1993-04-27
DK451284A (da) 1985-03-27
DK451284D0 (da) 1984-09-21
JPS60100580A (ja) 1985-06-04
IE842440L (en) 1985-03-26
KR850002097A (ko) 1985-05-06
GR80411B (en) 1985-01-16
EP0138417A2 (fr) 1985-04-24
DE3481615D1 (de) 1990-04-19
EP0138417B1 (fr) 1990-03-14
IE58095B1 (en) 1993-06-30
GB2146993A (en) 1985-05-01
JPH05194488A (ja) 1993-08-03

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Legal Events

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