CA1214739A - Fabrication et expression des genes codant pour l'urogastrone et analogues polypeptidiques - Google Patents
Fabrication et expression des genes codant pour l'urogastrone et analogues polypeptidiquesInfo
- Publication number
- CA1214739A CA1214739A CA000427372A CA427372A CA1214739A CA 1214739 A CA1214739 A CA 1214739A CA 000427372 A CA000427372 A CA 000427372A CA 427372 A CA427372 A CA 427372A CA 1214739 A CA1214739 A CA 1214739A
- Authority
- CA
- Canada
- Prior art keywords
- ctg
- gac
- urogastrone
- atg
- tac
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/485—Epidermal growth factor [EGF], i.e. urogastrone
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Toxicology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37550082A | 1982-05-06 | 1982-05-06 | |
| US375,500 | 1982-05-06 | ||
| US48609183A | 1983-04-25 | 1983-04-25 | |
| US486,091 | 1983-04-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1214739A true CA1214739A (fr) | 1986-12-02 |
Family
ID=27007082
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000427372A Expired CA1214739A (fr) | 1982-05-06 | 1983-05-04 | Fabrication et expression des genes codant pour l'urogastrone et analogues polypeptidiques |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0108132A1 (fr) |
| CA (1) | CA1214739A (fr) |
| IT (1) | IT1212984B (fr) |
| WO (1) | WO1983004030A1 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6331609B1 (en) | 1983-06-06 | 2001-12-18 | Genentech, Inc. | Preparation of human IGF via recombinant DNA technology |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4652639A (en) * | 1982-05-06 | 1987-03-24 | Amgen | Manufacture and expression of structural genes |
| US4710473A (en) * | 1983-08-10 | 1987-12-01 | Amgen, Inc. | DNA plasmids |
| US4870008A (en) * | 1983-08-12 | 1989-09-26 | Chiron Corporation | Secretory expression in eukaryotes |
| US4935370A (en) * | 1983-12-23 | 1990-06-19 | Pfizer Inc. | Expression plasmids for improved production of heterologous protein in bacteria |
| EP0147178B1 (fr) * | 1983-12-23 | 1991-08-14 | Pfizer Inc. | Plasmides d'expression pour la produciton de protéines héterologues dans des bactéries |
| US4745179A (en) * | 1984-04-02 | 1988-05-17 | Fujisawa Pharmaceutical Co., Ltd. | 59 Valine insulin-like growth factor I and process for production thereof |
| JP2554459B2 (ja) * | 1984-07-02 | 1996-11-13 | アース製薬 株式会社 | β−ウロガストロン遺伝子、対応プラスミド組換体及び対応形質転換体 |
| CA1263619A (fr) * | 1984-10-09 | 1989-12-05 | Ryuji Marumoto | Adn, production et utilisation |
| JP2549504B2 (ja) * | 1984-12-21 | 1996-10-30 | ア−ス製薬株式会社 | Ｄｎａ塩基配列、ポリペプチド分泌発現ベクター及び形質転換微生物 |
| US4743679A (en) * | 1986-02-24 | 1988-05-10 | Creative Biomolecules, Inc. | Process for producing human epidermal growth factor and analogs thereof |
| GB2188933A (en) * | 1986-04-10 | 1987-10-14 | Bayer Ag | Expression vectors for production of polypeptides, method for enhanced expression of polypeptides, hosts containing the expression vectors, products manufactured thereby |
| IN165717B (fr) * | 1986-08-07 | 1989-12-23 | Battelle Memorial Institute | |
| AU605291B2 (en) * | 1987-03-20 | 1991-01-10 | Micromet Ag | Process for the purification of recombinant polypeptides |
| US5013653A (en) | 1987-03-20 | 1991-05-07 | Creative Biomolecules, Inc. | Product and process for introduction of a hinge region into a fusion protein to facilitate cleavage |
| US5366081A (en) * | 1987-08-26 | 1994-11-22 | United States Surgical Corporation | Packaged synthetic absorbable surgical elements |
| US5472702A (en) * | 1987-08-26 | 1995-12-05 | United States Surgical Corporation | Sterilization of growth factors |
| IL89673A0 (en) * | 1988-03-24 | 1989-09-28 | Oncogen | Novel polypeptides having growth factor activity and nucleic acid sequences encoding the polypeptides |
| US5102789A (en) * | 1989-03-15 | 1992-04-07 | The Salk Institute Biotechnology/Industrial Associates, Inc. | Production of epideramal growth factor in pichia pastoris yeast cells |
| CA2059245C (fr) * | 1991-02-08 | 2004-07-06 | Michael P. Chesterfield | Methode et appareil permettant de laminer et d'enrober ou de remplir des jonctions |
| US5904716A (en) * | 1995-04-26 | 1999-05-18 | Gendler; El | Method for reconstituting cartilage tissue using demineralized bone and product thereof |
| US20090192554A1 (en) | 2008-01-29 | 2009-07-30 | Confluent Surgical, Inc. | Bioabsorbable block copolymer |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE53166B1 (en) * | 1980-08-05 | 1988-08-03 | Searle & Co | Synthetic urogastrone gene,corresponding plasmid recombinants,transformed cells,production thereof and urogastrone expression |
-
1983
- 1983-05-02 WO PCT/US1983/000650 patent/WO1983004030A1/fr unknown
- 1983-05-02 EP EP83901992A patent/EP0108132A1/fr not_active Withdrawn
- 1983-05-04 CA CA000427372A patent/CA1214739A/fr not_active Expired
- 1983-05-06 IT IT8367501A patent/IT1212984B/it active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6331609B1 (en) | 1983-06-06 | 2001-12-18 | Genentech, Inc. | Preparation of human IGF via recombinant DNA technology |
| US6331414B1 (en) | 1983-06-06 | 2001-12-18 | Genentech, Inc. | Preparation of human IGF via recombinant DNA technology |
| USRE39355E1 (en) * | 1983-06-06 | 2006-10-17 | Genetech, Inc. | Preparation of human IGF via recombinant DNA technology |
Also Published As
| Publication number | Publication date |
|---|---|
| IT8367501A0 (it) | 1983-05-06 |
| EP0108132A1 (fr) | 1984-05-16 |
| IT1212984B (it) | 1989-12-07 |
| WO1983004030A1 (fr) | 1983-11-24 |
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| MKEX | Expiry |