CA1194469A - Salification products of cholic acids, process for their preparation and therapeutic compositions containing them as active principle - Google Patents

Salification products of cholic acids, process for their preparation and therapeutic compositions containing them as active principle

Info

Publication number
CA1194469A
CA1194469A CA000402296A CA402296A CA1194469A CA 1194469 A CA1194469 A CA 1194469A CA 000402296 A CA000402296 A CA 000402296A CA 402296 A CA402296 A CA 402296A CA 1194469 A CA1194469 A CA 1194469A
Authority
CA
Canada
Prior art keywords
acid
salt
trimebutyne
molar ratio
cholic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000402296A
Other languages
English (en)
French (fr)
Inventor
Antonio Bonaldi
Vanna Springolo
Egidio Molinari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Erregierre SpA
Original Assignee
Erregierre SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erregierre SpA filed Critical Erregierre SpA
Application granted granted Critical
Publication of CA1194469A publication Critical patent/CA1194469A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
CA000402296A 1981-05-21 1982-05-05 Salification products of cholic acids, process for their preparation and therapeutic compositions containing them as active principle Expired CA1194469A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT21867A/81 1981-05-21
IT21867/81A IT1136624B (it) 1981-05-21 1981-05-21 Prodotti di salificazione di acidi colici,processo per la loro preparazione e composizioni terapeutiche che li comprendono come principio attivo

Publications (1)

Publication Number Publication Date
CA1194469A true CA1194469A (en) 1985-10-01

Family

ID=11187975

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000402296A Expired CA1194469A (en) 1981-05-21 1982-05-05 Salification products of cholic acids, process for their preparation and therapeutic compositions containing them as active principle

Country Status (13)

Country Link
US (1) US4404199A (env)
EP (1) EP0065666B1 (env)
JP (1) JPS57203098A (env)
AT (1) ATE11528T1 (env)
CA (1) CA1194469A (env)
DE (1) DE3262109D1 (env)
DK (1) DK159456C (env)
ES (1) ES512391A0 (env)
IE (1) IE52917B1 (env)
IT (1) IT1136624B (env)
NO (1) NO158423C (env)
PT (1) PT74864B (env)
YU (1) YU43516B (env)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1152801B (it) * 1982-08-17 1987-01-14 Proter Spa Composti steroidei ad attivita' coleretica, processo per la loro preparazione e composizioni terapeutiche che li contengono come principio attivo
US5753269A (en) * 1995-12-27 1998-05-19 Bayer Corporation Otic microbial combinations
IL139241A0 (en) 1998-05-13 2001-11-25 Novo Nordisk As Meiosis regulating compounds
US20020119921A1 (en) * 1999-03-31 2002-08-29 Michael Streit Thrombospondin-2 and uses thereof
AU2001231196A1 (en) * 2000-01-27 2001-08-07 The General Hospital Corporation Delivery of therapeutic biological from implantable tissue matrices
BR112017001623B1 (pt) * 2014-07-29 2022-11-29 Shenzhen Hightide Biopharmaceutical, Ltd Sal de adição ácido-base em uma forma substancialmente pura, composição farmacêutica compreendendo uma quantidade do referido sal e seus usos

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2369M (fr) * 1962-10-17 1964-03-02 Jouveinal Lab Nouveau médicament contre les troubles du systeme nerveux central.
GB1532413A (en) * 1974-12-23 1978-11-15 Union International Co Ltd Chenodeoxycholic acid
GB1431709A (en) * 1973-12-03 1976-04-14 Prodotti Antibiotici Spa Lysozyme derivatives
FR2358144A1 (fr) * 1976-07-13 1978-02-10 Lipha Nouvelle composition medicamenteuse pour le traitement de la lithiase biliaire
US4186143A (en) * 1977-06-20 1980-01-29 Canada Packers Limited Chenodeoxycholic acid recovery process
JPS5529075A (en) * 1978-08-24 1980-03-01 Suzuki Motor Co Ltd Crank room oil recoverer for 2-cycle engine
US4241047A (en) * 1979-07-18 1980-12-23 Lipha, Lyonnaise Industrielle Pharmaceutique Novel medicinal composition for the treatment of biliary lithiasis

Also Published As

Publication number Publication date
PT74864B (fr) 1983-12-07
JPS6312478B2 (env) 1988-03-18
IE52917B1 (en) 1988-04-13
JPS57203098A (en) 1982-12-13
EP0065666A1 (en) 1982-12-01
DE3262109D1 (en) 1985-03-14
IE821056L (en) 1982-11-21
NO158423B (no) 1988-05-30
US4404199A (en) 1983-09-13
NO821672L (no) 1982-11-22
IT8121867A0 (it) 1981-05-21
NO158423C (no) 1988-09-14
ATE11528T1 (de) 1985-02-15
DK159456C (da) 1991-03-18
ES8302735A1 (es) 1983-02-01
ES512391A0 (es) 1983-02-01
PT74864A (fr) 1982-06-01
DK159456B (da) 1990-10-15
DK226882A (da) 1982-11-22
YU106582A (en) 1984-10-31
IT1136624B (it) 1986-09-03
YU43516B (en) 1989-08-31
EP0065666B1 (en) 1985-01-30

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Legal Events

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