CA1148147A - Purification of l-aspartyl-l- phenylalanine alkyl esters - Google Patents

Purification of l-aspartyl-l- phenylalanine alkyl esters

Info

Publication number
CA1148147A
CA1148147A CA000360826A CA360826A CA1148147A CA 1148147 A CA1148147 A CA 1148147A CA 000360826 A CA000360826 A CA 000360826A CA 360826 A CA360826 A CA 360826A CA 1148147 A CA1148147 A CA 1148147A
Authority
CA
Canada
Prior art keywords
aspartyl
phenylalanine
ester
process according
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000360826A
Other languages
English (en)
French (fr)
Inventor
Fredric J. Vinick
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Danisco Finland Oy
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of CA1148147A publication Critical patent/CA1148147A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/801—Peptide sweetners

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Seasonings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
CA000360826A 1979-10-29 1980-09-23 Purification of l-aspartyl-l- phenylalanine alkyl esters Expired CA1148147A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/089,640 US4238392A (en) 1979-10-29 1979-10-29 Purification of L-aspartyl-L-phenylalanine alkyl esters
US89,640 1979-10-29

Publications (1)

Publication Number Publication Date
CA1148147A true CA1148147A (en) 1983-06-14

Family

ID=22218770

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000360826A Expired CA1148147A (en) 1979-10-29 1980-09-23 Purification of l-aspartyl-l- phenylalanine alkyl esters

Country Status (16)

Country Link
US (1) US4238392A (oth)
EP (1) EP0030076B1 (oth)
JP (1) JPS5855135B2 (oth)
AT (1) ATE5069T1 (oth)
AU (1) AU519719B2 (oth)
CA (1) CA1148147A (oth)
DE (1) DE3065387D1 (oth)
DK (1) DK147622C (oth)
ES (1) ES496351A0 (oth)
GR (1) GR70665B (oth)
IE (1) IE50537B1 (oth)
IN (1) IN154693B (oth)
PH (1) PH15276A (oth)
PL (1) PL127338B1 (oth)
YU (1) YU41007B (oth)
ZA (1) ZA806612B (oth)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4820729A (en) * 1981-03-30 1989-04-11 Rorer Pharmaceutical Corporation N-substituted-amido-amino acids
GB0210446D0 (en) * 2002-05-08 2002-06-12 3M Innovative Properties Co Conformable pouch reservoir for spray gun
WO2005020930A2 (en) * 2003-09-02 2005-03-10 Danisco A/S Improved syntheses of alitame

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4941425B1 (oth) * 1970-10-26 1974-11-08
US4031258A (en) * 1972-03-30 1977-06-21 General Foods Corporation Inorganic salts of dipeptide sweeteners
US4173562A (en) * 1976-12-27 1979-11-06 Monsanto Company Process for the preparation of α-L-aspartyl-L-phenylalanine methyl ester

Also Published As

Publication number Publication date
ES8107158A1 (es) 1981-10-01
IE802220L (en) 1981-04-29
IE50537B1 (en) 1986-05-14
AU6376380A (en) 1981-05-07
YU274780A (en) 1982-10-31
US4238392A (en) 1980-12-09
IN154693B (oth) 1984-12-08
JPS5673053A (en) 1981-06-17
ZA806612B (en) 1982-01-27
GR70665B (oth) 1982-12-06
DE3065387D1 (en) 1983-11-24
PH15276A (en) 1982-11-02
ES496351A0 (es) 1981-10-01
ATE5069T1 (de) 1983-11-15
EP0030076B1 (en) 1983-10-19
EP0030076A1 (en) 1981-06-10
DK147622C (da) 1985-04-22
DK391980A (da) 1981-04-30
DK147622B (da) 1984-10-22
PL227475A1 (oth) 1981-07-10
YU41007B (en) 1986-10-31
AU519719B2 (en) 1981-12-17
JPS5855135B2 (ja) 1983-12-08
PL127338B1 (en) 1983-10-31

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Legal Events

Date Code Title Description
MKEX Expiry