CA1143289A - Microparticle drug delivery system - Google Patents

Microparticle drug delivery system

Info

Publication number
CA1143289A
CA1143289A CA000336744A CA336744A CA1143289A CA 1143289 A CA1143289 A CA 1143289A CA 000336744 A CA000336744 A CA 000336744A CA 336744 A CA336744 A CA 336744A CA 1143289 A CA1143289 A CA 1143289A
Authority
CA
Canada
Prior art keywords
microparticles
hormone
antigen
matrix material
uterus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000336744A
Other languages
English (en)
French (fr)
Inventor
Lee R. Beck
Albert C. Tanwuary
Donald R. Cowsar
Charles E. Flowers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Stolle Research and Development Corp
Original Assignee
Stolle Research and Development Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stolle Research and Development Corp filed Critical Stolle Research and Development Corp
Application granted granted Critical
Publication of CA1143289A publication Critical patent/CA1143289A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04—Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Reproductive Health (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gynecology & Obstetrics (AREA)
  • Dispersion Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA000336744A 1978-10-17 1979-10-01 Microparticle drug delivery system Expired CA1143289A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US95210978A 1978-10-17 1978-10-17
US952,109 1978-10-17
US96738078A 1978-12-07 1978-12-07
US967,380 1978-12-07

Publications (1)

Publication Number Publication Date
CA1143289A true CA1143289A (en) 1983-03-22

Family

ID=27130325

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000336744A Expired CA1143289A (en) 1978-10-17 1979-10-01 Microparticle drug delivery system

Country Status (13)

Country Link
AU (1) AU528186B2 (de)
CA (1) CA1143289A (de)
CH (1) CH645545A5 (de)
DE (1) DE2940146A1 (de)
FR (1) FR2439014A1 (de)
GB (1) GB2034182B (de)
IE (1) IE48851B1 (de)
IL (1) IL58471A (de)
IT (1) IT1124572B (de)
NL (1) NL184723C (de)
NZ (1) NZ191837A (de)
PH (1) PH25638A (de)
SE (1) SE7908520L (de)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5922340A (en) 1992-09-10 1999-07-13 Children's Medical Center Corporation High load formulations and methods for providing prolonged local anesthesia
US5942241A (en) 1995-06-09 1999-08-24 Euro-Celtique, S.A. Formulations and methods for providing prolonged local anesthesia
US6046187A (en) 1996-09-16 2000-04-04 Children's Medical Center Corporation Formulations and methods for providing prolonged local anesthesia
US6248345B1 (en) 1997-07-02 2001-06-19 Euro-Celtique, S.A. Prolonged anesthesia in joints and body spaces
US6699908B2 (en) 1996-06-24 2004-03-02 Euro-Celtique, S.A. Methods for providing safe local anesthesia

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4675189A (en) * 1980-11-18 1987-06-23 Syntex (U.S.A.) Inc. Microencapsulation of water soluble active polypeptides
US5366734A (en) * 1981-02-16 1994-11-22 Zeneca Limited Continuous release pharmaceutical compositions
CH661206A5 (fr) * 1983-09-23 1987-07-15 Debiopharm Sa Procede pour la preparation d'un medicament destine au traitement de maladies hormonodependantes.
US4816257A (en) * 1985-09-20 1989-03-28 Research & Education Institute, Harbor-Ucla Medical Center Inc. Method for producing an in vivo environment suitable for human embryo transfer
US5688519A (en) * 1987-04-06 1997-11-18 Leonard; Robert J. Flash-flow fused medicinal implants
US5000886A (en) * 1987-05-26 1991-03-19 American Cyanamid Company Silicone-hardened pharmaceutical microcapsules and process of making the same
DE3785033T2 (de) * 1987-07-21 1993-10-07 Stolle Res & Dev Verfahren zum Erhalten von immunregulierenden Faktoren mittels Säugetierimmunisierung.
US4897268A (en) * 1987-08-03 1990-01-30 Southern Research Institute Drug delivery system and method of making the same
FR2620335A1 (fr) * 1987-09-15 1989-03-17 Berdal Pascal Presentation pharmaceutique potentialisant l'effet cytotrophique des serums et/ou des anticorps antitissus animaux et/ou humains
US5084277A (en) * 1988-08-30 1992-01-28 Greco John C Vaginal progesterone tablet

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3887699A (en) * 1969-03-24 1975-06-03 Seymour Yolles Biodegradable polymeric article for dispensing drugs
US3594468A (en) * 1969-04-01 1971-07-20 Vincent R Saurino Germicidal compositions
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US3875300A (en) * 1972-12-18 1975-04-01 Ortho Pharma Corp Composition for sustained release of a medicament and method of using same
AU513400B2 (en) * 1976-03-04 1980-11-27 Commonwealth Serum Laboratories Commission Biodegradable, sustained release composition

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5922340A (en) 1992-09-10 1999-07-13 Children's Medical Center Corporation High load formulations and methods for providing prolonged local anesthesia
US6238702B1 (en) 1992-09-10 2001-05-29 Children's Medical Center Corp. High load formulations and methods for providing prolonged local anesthesia
US5942241A (en) 1995-06-09 1999-08-24 Euro-Celtique, S.A. Formulations and methods for providing prolonged local anesthesia
US6514516B1 (en) 1995-06-09 2003-02-04 Euro-Celtique, S.A. Formulations and methods for providing prolonged local anesthesia
US6521259B1 (en) 1995-06-09 2003-02-18 Euro-Celtique S.A. Formulations and methods for providing prolonged local anesthesia
US6699908B2 (en) 1996-06-24 2004-03-02 Euro-Celtique, S.A. Methods for providing safe local anesthesia
US6046187A (en) 1996-09-16 2000-04-04 Children's Medical Center Corporation Formulations and methods for providing prolonged local anesthesia
US6426339B1 (en) 1996-09-16 2002-07-30 Children's Medical Center Corporation Formulations and methods for providing prolonged local anesthesia
US6248345B1 (en) 1997-07-02 2001-06-19 Euro-Celtique, S.A. Prolonged anesthesia in joints and body spaces
US6534081B2 (en) 1997-07-02 2003-03-18 Euro-Celtique S.A. Prolonged anesthesia in joints and body spaces

Also Published As

Publication number Publication date
IT7926288A0 (it) 1979-10-05
IE791966L (en) 1980-04-17
SE7908520L (sv) 1980-04-18
FR2439014A1 (fr) 1980-05-16
PH25638A (en) 1991-08-31
AU5169679A (en) 1980-04-24
GB2034182A (en) 1980-06-04
NZ191837A (en) 1984-07-31
FR2439014B1 (de) 1983-12-09
GB2034182B (en) 1983-07-27
DE2940146C2 (de) 1991-12-05
NL7907432A (nl) 1980-04-21
IT1124572B (it) 1986-05-07
DE2940146A1 (de) 1980-04-30
CH645545A5 (de) 1984-10-15
IL58471A0 (en) 1980-01-31
IL58471A (en) 1983-05-15
AU528186B2 (en) 1983-04-21
NL184723B (nl) 1989-05-16
NL184723C (nl) 1989-10-16
IE48851B1 (en) 1985-05-29

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Legal Events

Date Code Title Description
MKEX Expiry