CA1136138A - Cephalosporin analogs and methods for production thereof - Google Patents
Cephalosporin analogs and methods for production thereofInfo
- Publication number
- CA1136138A CA1136138A CA000342597A CA342597A CA1136138A CA 1136138 A CA1136138 A CA 1136138A CA 000342597 A CA000342597 A CA 000342597A CA 342597 A CA342597 A CA 342597A CA 1136138 A CA1136138 A CA 1136138A
- Authority
- CA
- Canada
- Prior art keywords
- group
- carbon atoms
- compound
- process according
- reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
- C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
- C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
- C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
- C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP53162008A JPS6058920B2 (ja) | 1978-12-26 | 1978-12-26 | セフアロスポリン類縁体 |
JP162,008/78 | 1978-12-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA1136138A true CA1136138A (en) | 1982-11-23 |
Family
ID=15746283
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA000342597A Expired CA1136138A (en) | 1978-12-26 | 1979-12-21 | Cephalosporin analogs and methods for production thereof |
Country Status (9)
Country | Link |
---|---|
JP (1) | JPS6058920B2 (de) |
CA (1) | CA1136138A (de) |
CH (1) | CH642968A5 (de) |
DE (1) | DE2952413C2 (de) |
DK (1) | DK549479A (de) |
FR (1) | FR2445327A1 (de) |
GB (1) | GB2041923B (de) |
IT (1) | IT1192795B (de) |
NO (1) | NO794177L (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0653739B2 (ja) * | 1984-11-15 | 1994-07-20 | 協和醗酵工業株式会社 | 3位置換カルバセフエム化合物 |
US4673737A (en) * | 1985-08-02 | 1987-06-16 | Harvard University | 7-acylamino-(or 7-amino)-3-trifluoromethylsulfonyloxy-1-carba(1-dethia)-3-cephem-4-carboxylic acids and esters thereof |
JPS63184229U (de) * | 1987-05-19 | 1988-11-28 | ||
US4885291A (en) * | 1988-01-14 | 1989-12-05 | Eli Lilly And Company | 1-carba(dethia)-3-cephem derivatives |
US4977257A (en) * | 1988-11-14 | 1990-12-11 | Eli Lilly And Company | DMF solvates of a β-lactam antibiotic |
US5077287A (en) * | 1991-01-18 | 1991-12-31 | Eli Lilly And Company | 3-thiazolylthio carbacephem antibacterial agents |
CA2067708A1 (en) * | 1991-05-10 | 1992-11-11 | Richard A. Berglund | Process for preparing doubly blocked 1-carba(1-dethia)-3-cephem-4-carboxylic acids |
DE4331391A1 (de) * | 1993-09-15 | 1995-03-16 | Josef Dr Kemmer | Halbleiter(detektor)struktur |
WO2004037163A2 (en) * | 2002-05-14 | 2004-05-06 | Northwestern University | STERICALLY-AWKWARD β-LACTAMASE INHIBITORS |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2714880A1 (de) * | 1977-04-02 | 1978-10-26 | Hoechst Ag | Cephemderivate und verfahren zu ihrer herstellung |
-
1978
- 1978-12-26 JP JP53162008A patent/JPS6058920B2/ja not_active Expired
-
1979
- 1979-12-19 NO NO794177A patent/NO794177L/no unknown
- 1979-12-20 CH CH1134579A patent/CH642968A5/de not_active IP Right Cessation
- 1979-12-21 CA CA000342597A patent/CA1136138A/en not_active Expired
- 1979-12-21 FR FR7931527A patent/FR2445327A1/fr active Granted
- 1979-12-21 DK DK549479A patent/DK549479A/da not_active Application Discontinuation
- 1979-12-21 GB GB7944080A patent/GB2041923B/en not_active Expired
- 1979-12-24 IT IT69476/79A patent/IT1192795B/it active
- 1979-12-27 DE DE2952413A patent/DE2952413C2/de not_active Expired
Also Published As
Publication number | Publication date |
---|---|
JPS6058920B2 (ja) | 1985-12-23 |
FR2445327A1 (fr) | 1980-07-25 |
NO794177L (no) | 1980-06-27 |
DE2952413C2 (de) | 1986-12-11 |
JPS5587791A (en) | 1980-07-02 |
DE2952413A1 (de) | 1980-07-17 |
GB2041923A (en) | 1980-09-17 |
CH642968A5 (de) | 1984-05-15 |
DK549479A (da) | 1980-06-27 |
GB2041923B (en) | 1983-07-20 |
IT1192795B (it) | 1988-05-04 |
FR2445327B1 (de) | 1983-05-06 |
IT7969476A0 (it) | 1979-12-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MKEX | Expiry |