CA1120031A - Tetrapeptides et methode de preparation - Google Patents

Tetrapeptides et methode de preparation

Info

Publication number
CA1120031A
CA1120031A CA000317547A CA317547A CA1120031A CA 1120031 A CA1120031 A CA 1120031A CA 000317547 A CA000317547 A CA 000317547A CA 317547 A CA317547 A CA 317547A CA 1120031 A CA1120031 A CA 1120031A
Authority
CA
Canada
Prior art keywords
amino
alpha
resin
protected
glutamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000317547A
Other languages
English (en)
Inventor
Gideon Goldstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ortho Pharmaceutical Corp
Original Assignee
Ortho Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/960,550 external-priority patent/US4232008A/en
Application filed by Ortho Pharmaceutical Corp filed Critical Ortho Pharmaceutical Corp
Application granted granted Critical
Publication of CA1120031A publication Critical patent/CA1120031A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1021—Tetrapeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C07K7/062—Serum thymic factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA000317547A 1977-12-08 1978-12-07 Tetrapeptides et methode de preparation Expired CA1120031A (fr)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US85849677A 1977-12-08 1977-12-08
US858,496 1977-12-08
US94053178A 1978-09-08 1978-09-08
US940,531 1978-09-08
US05/960,550 US4232008A (en) 1978-11-17 1978-11-17 Tetrapeptides and methods
US960,550 1978-11-17

Publications (1)

Publication Number Publication Date
CA1120031A true CA1120031A (fr) 1982-03-16

Family

ID=27420392

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000317547A Expired CA1120031A (fr) 1977-12-08 1978-12-07 Tetrapeptides et methode de preparation

Country Status (19)

Country Link
JP (1) JPS5498719A (fr)
CA (1) CA1120031A (fr)
CH (1) CH642058A5 (fr)
DE (1) DE2853002A1 (fr)
DK (1) DK149595C (fr)
ES (1) ES475857A1 (fr)
FI (1) FI67368C (fr)
FR (1) FR2411174A1 (fr)
GB (1) GB2014581B (fr)
GR (1) GR65013B (fr)
IE (1) IE47611B1 (fr)
IL (1) IL56150A (fr)
IT (1) IT1110889B (fr)
NL (1) NL7812004A (fr)
NO (1) NO149631C (fr)
NZ (1) NZ189101A (fr)
PT (1) PT68883A (fr)
SE (1) SE444687B (fr)
YU (1) YU41322B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4215112A (en) * 1979-03-14 1980-07-29 Ortho Pharmaceutical Corporation Tripeptides and methods
US4215111A (en) * 1979-03-14 1980-07-29 Ortho Pharmaceutical Corporation Peptides having ubiquitin-like activity
CA1156220A (fr) * 1979-04-26 1983-11-01 George Heavner Methode et composition pour la preparation de h-sar-lys-sar-gln-nh.sub.2
US4426324A (en) * 1979-09-28 1984-01-17 Hoffmann-La Roche Inc. Immunopotentiating peptides
JPS5711950A (en) 1980-06-25 1982-01-21 Kureha Chem Ind Co Ltd Peptide and its synthesis
FR2546164B1 (fr) * 1983-05-16 1987-07-17 Centre Nat Rech Scient Nouveaux derives de peptides, leur preparation et leur application comme inhibiteurs de l'elastase
FR2741076B1 (fr) 1995-11-15 1998-01-30 Rech De Pathologie Appliquee S Conjugues peptidiques derives des hormones thymiques, leur utilisation a titre de medicament et compositions les contenant
RU2210382C1 (ru) * 2002-07-09 2003-08-20 Терентьев Александр Александрович Пептид, обладающий иммунорегуляторным свойством, и его композиция

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2544348C3 (de) * 1975-10-03 1979-12-13 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V., 3400 Goettingen L-Leucin-13-Motilin, Verfahren zu dessen Herstellung und dasselbe enthaltendes Mittel
IT1156766B (it) * 1977-05-25 1987-02-04 Anvar Polipeptidi dotati di attivita' timica o antagonista e procedimento per la loro sintesi
FR2391994A1 (fr) * 1977-05-25 1978-12-22 Anvar Nouveaux polypeptides a activite thymique ou a activite antagoniste et leurs procedes de synthese
FR2423481A2 (fr) * 1978-04-21 1979-11-16 Anvar Nouveaux polypeptides a activite thymique ou a activite antagoniste et leurs procedes de synthese

Also Published As

Publication number Publication date
NO784128L (no) 1979-06-11
GB2014581B (en) 1982-05-19
FR2411174A1 (fr) 1979-07-06
NZ189101A (en) 1984-07-06
DK554078A (da) 1979-06-09
IT7852239A0 (it) 1978-12-07
IE47611B1 (en) 1984-05-02
YU288078A (en) 1983-02-28
NO149631C (no) 1984-05-23
FR2411174B1 (fr) 1984-05-25
PT68883A (en) 1979-01-01
FI783769A (fi) 1979-06-09
IT1110889B (it) 1986-01-06
ES475857A1 (es) 1980-01-16
JPS6327360B2 (fr) 1988-06-02
SE7812614L (sv) 1979-06-09
FI67368B (fi) 1984-11-30
DE2853002A1 (de) 1979-06-13
FI67368C (fi) 1985-03-11
NO149631B (no) 1984-02-13
GB2014581A (en) 1979-08-30
DK149595B (da) 1986-08-04
JPS5498719A (en) 1979-08-03
NL7812004A (nl) 1979-06-12
IL56150A0 (en) 1979-03-12
IE782423L (en) 1979-06-08
DK149595C (da) 1987-03-23
GR65013B (en) 1980-06-12
SE444687B (sv) 1986-04-28
YU41322B (en) 1987-02-28
CH642058A5 (de) 1984-03-30
IL56150A (en) 1982-02-28

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Legal Events

Date Code Title Description
MKEX Expiry