CA1105009A - Ergot derivatives - Google Patents

Ergot derivatives

Info

Publication number
CA1105009A
CA1105009A CA299,678A CA299678A CA1105009A CA 1105009 A CA1105009 A CA 1105009A CA 299678 A CA299678 A CA 299678A CA 1105009 A CA1105009 A CA 1105009A
Authority
CA
Canada
Prior art keywords
carbon atoms
compound
alkyl
formula
acid addition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA299,678A
Other languages
English (en)
French (fr)
Inventor
Hartmut Hauth
Peter Gull
Paul Pfaffli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Application granted granted Critical
Publication of CA1105009A publication Critical patent/CA1105009A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA299,678A 1977-03-25 1978-03-23 Ergot derivatives Expired CA1105009A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH3814/77 1977-03-25
CH381477A CH628049A5 (en) 1977-03-25 1977-03-25 Process for the preparation of ergolene derivatives

Publications (1)

Publication Number Publication Date
CA1105009A true CA1105009A (en) 1981-07-14

Family

ID=4264035

Family Applications (1)

Application Number Title Priority Date Filing Date
CA299,678A Expired CA1105009A (en) 1977-03-25 1978-03-23 Ergot derivatives

Country Status (20)

Country Link
JP (1) JPS53119898A (xx)
AT (1) AT366685B (xx)
AU (1) AU520738B2 (xx)
BE (1) BE865267A (xx)
CA (1) CA1105009A (xx)
CH (1) CH628049A5 (xx)
DE (1) DE2810774A1 (xx)
DK (1) DK147072C (xx)
ES (1) ES468133A1 (xx)
FI (1) FI66375C (xx)
GB (1) GB1596210A (xx)
IE (1) IE46688B1 (xx)
IL (1) IL54342A (xx)
IT (1) IT1104183B (xx)
NL (1) NL7803031A (xx)
NZ (1) NZ186775A (xx)
PT (1) PT67816A (xx)
SE (1) SE7803040L (xx)
SU (1) SU1053755A3 (xx)
ZA (1) ZA781714B (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3205169A1 (de) * 1981-02-24 1982-10-14 Sandoz-Patent-GmbH, 7850 Lörrach Neue ergolinderivate, deren herstellung und deren pharmazeutische zusammensetzungen
DE3411981A1 (de) * 1984-03-28 1985-10-10 Schering AG, Berlin und Bergkamen, 1000 Berlin Verfahren zur herstellung von 2.3-dihydroergolinen
GB2173189B (en) * 1985-02-21 1988-04-27 Maruko Pharmaceutical Co Ergoline derivatives and salts thereof and pharmaceutical compositions thereof
US4798834A (en) * 1987-08-31 1989-01-17 Eli Lilly And Company Optionally substituted (3β-9,10-didehydro-2,3-dihydro ergoline as serotonergic function enhancement

Also Published As

Publication number Publication date
IT1104183B (it) 1985-10-21
FI66375C (fi) 1984-10-10
SU1053755A3 (ru) 1983-11-07
BE865267A (fr) 1978-09-25
DK119778A (da) 1978-09-26
SE7803040L (sv) 1978-09-26
AT366685B (de) 1982-04-26
ATA207078A (de) 1981-09-15
DE2810774A1 (de) 1978-10-05
DK147072C (da) 1984-09-10
NZ186775A (en) 1980-12-19
ZA781714B (en) 1979-11-28
AU3448378A (en) 1979-09-27
IE46688B1 (en) 1983-08-24
IE780580L (en) 1978-09-25
CH628049A5 (en) 1982-02-15
IL54342A (en) 1981-02-27
FI66375B (fi) 1984-06-29
AU520738B2 (en) 1982-02-25
GB1596210A (en) 1981-08-19
IL54342A0 (en) 1978-06-15
DK147072B (da) 1984-04-02
PT67816A (fr) 1978-04-01
IT7848557A0 (it) 1978-03-23
NL7803031A (nl) 1978-09-27
ES468133A1 (es) 1980-06-16
FI780835A (fi) 1978-09-26
JPS53119898A (en) 1978-10-19

Similar Documents

Publication Publication Date Title
US3388129A (en) 1-methyl ergot alkaloids
US3332950A (en) 14-hydroxydihydronormorphinone derivatives
CA1150253A (en) Dibenzoimidazoazepines, -oxazepines and -thiazepines and pharmaceutical compositions containing them
CA1288427C (en) Substituted pyrroles with opioid receptor activity
US3995039A (en) Pyrazolo [1,5-a] [1,3,5] triazines
KR100354654B1 (ko) 피리미디논 화합물, 이를 함유하는 약제학적 조성물 및이의 제조 방법.
NZ206945A (en) Pyridazines and pharmaceutical compositions
CA1105009A (en) Ergot derivatives
GB1579035A (en) (3-amino-5-substituted-6-fluoropyrazinoyl or pyrazinamino) guanidines adn their derivatives bearing substituents on the guanidine nitrogens
HU203344B (en) Process for producing cycloalkylamide derivatives of (8beta)-1-alkyl-6-substituted ergolines
US4308207A (en) Morphanthridine derivatives
US6355647B1 (en) 3-substituted 3,4,5,7-tetrahedropyrrolo[3′,4′:4,5]thieno-[2,3-d]pyrimidine derivatives, their preparation and use
US3925369A (en) New tricyclic ureas processes for their production and pharmaceutical compositions
US3666762A (en) 2{40 {62 -ISOPROPYL-5{40 {60 -n-PROPYL-9,10-DIHYDRO-ERGOPEPTINES
CA1092108A (en) Oxadiazolopyrimidine derivatives
US4180581A (en) N-9,10-dihydrolysergyl-m-aminobenzoic acid amide derivative
US3852292A (en) 2-(pyridyl)-imidazole-4,5-dicarboxylic acid and derivatives
CA1243670A (en) Process for preparing piperazin-l-yl-ergoline derivatives
CA1068268A (en) Derivatives of benzocycloheptathiophene
CA1287624C (en) Ergolinyl heterocycles
US4495189A (en) Condensed pyrimidines
AU698384B2 (en) Thiazoline derivatives
US3772306A (en) 1,2,4a,5,6,8,9,14,14a,14b-decahydrobenz(a)indolo(2,3-g)quinolizin-3(4h)-ones
US3592816A (en) N-substituted piperazides of lysergic acid
CA1109864A (en) Ergoline derivatives

Legal Events

Date Code Title Description
MKEX Expiry