IE780580L - Ergot derivatives - Google Patents
Ergot derivativesInfo
- Publication number
- IE780580L IE780580L IE780580A IE58078A IE780580L IE 780580 L IE780580 L IE 780580L IE 780580 A IE780580 A IE 780580A IE 58078 A IE58078 A IE 58078A IE 780580 L IE780580 L IE 780580L
- Authority
- IE
- Ireland
- Prior art keywords
- formula
- carbon atoms
- salts
- ergot derivatives
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
A description is given of the preparation of ergolene derivatives with an action lowering blood pressure and the formula I <IMAGE> in which R1 and R2 are each hydrogen or an alkyl group with 1 to 4 carbon atoms, or else together form an alkylidene chain with a maximum of 5 carbon atoms, and their salts with acids. Corresponding compounds unsaturated in position 2,3 are reduced selectively in position 2,3 and the resulting compounds of the formula I are converted where appropriate into their acid addition salts.
[GB1596210A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH381477A CH628049A5 (en) | 1977-03-25 | 1977-03-25 | Process for the preparation of ergolene derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE780580L true IE780580L (en) | 1978-09-25 |
| IE46688B1 IE46688B1 (en) | 1983-08-24 |
Family
ID=4264035
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE580/78A IE46688B1 (en) | 1977-03-25 | 1978-03-23 | N-(2,3 -dihydro-9-ergolen-8 -yl methyl)ureas |
Country Status (20)
| Country | Link |
|---|---|
| JP (1) | JPS53119898A (en) |
| AT (1) | AT366685B (en) |
| AU (1) | AU520738B2 (en) |
| BE (1) | BE865267A (en) |
| CA (1) | CA1105009A (en) |
| CH (1) | CH628049A5 (en) |
| DE (1) | DE2810774A1 (en) |
| DK (1) | DK147072C (en) |
| ES (1) | ES468133A1 (en) |
| FI (1) | FI66375C (en) |
| GB (1) | GB1596210A (en) |
| IE (1) | IE46688B1 (en) |
| IL (1) | IL54342A (en) |
| IT (1) | IT1104183B (en) |
| NL (1) | NL7803031A (en) |
| NZ (1) | NZ186775A (en) |
| PT (1) | PT67816A (en) |
| SE (1) | SE7803040L (en) |
| SU (1) | SU1053755A3 (en) |
| ZA (1) | ZA781714B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3205169A1 (en) * | 1981-02-24 | 1982-10-14 | Sandoz-Patent-GmbH, 7850 Lörrach | NEW ERGOL DERIVATIVES, THEIR PRODUCTION AND THEIR PHARMACEUTICAL COMPOSITIONS |
| DE3411981A1 (en) * | 1984-03-28 | 1985-10-10 | Schering AG, Berlin und Bergkamen, 1000 Berlin | METHOD FOR PRODUCING 2.3-DIHYDROERGOLINES |
| GB2173189B (en) * | 1985-02-21 | 1988-04-27 | Maruko Pharmaceutical Co | Ergoline derivatives and salts thereof and pharmaceutical compositions thereof |
| US4798834A (en) * | 1987-08-31 | 1989-01-17 | Eli Lilly And Company | Optionally substituted (3β-9,10-didehydro-2,3-dihydro ergoline as serotonergic function enhancement |
-
1977
- 1977-03-25 CH CH381477A patent/CH628049A5/en not_active IP Right Cessation
-
1978
- 1978-03-13 DE DE19782810774 patent/DE2810774A1/en not_active Withdrawn
- 1978-03-16 FI FI780835A patent/FI66375C/en not_active IP Right Cessation
- 1978-03-16 SE SE7803040A patent/SE7803040L/en unknown
- 1978-03-16 DK DK119778A patent/DK147072C/en not_active IP Right Cessation
- 1978-03-21 GB GB11112/78A patent/GB1596210A/en not_active Expired
- 1978-03-21 NL NL7803031A patent/NL7803031A/en not_active Application Discontinuation
- 1978-03-22 ES ES468133A patent/ES468133A1/en not_active Expired
- 1978-03-23 IE IE580/78A patent/IE46688B1/en unknown
- 1978-03-23 ZA ZA00781714A patent/ZA781714B/en unknown
- 1978-03-23 AU AU34483/78A patent/AU520738B2/en not_active Expired
- 1978-03-23 CA CA299,678A patent/CA1105009A/en not_active Expired
- 1978-03-23 IT IT48557/78A patent/IT1104183B/en active
- 1978-03-23 AT AT0207078A patent/AT366685B/en not_active IP Right Cessation
- 1978-03-23 BE BE186239A patent/BE865267A/en not_active IP Right Cessation
- 1978-03-23 NZ NZ186775A patent/NZ186775A/en unknown
- 1978-03-23 PT PT67816A patent/PT67816A/en unknown
- 1978-03-23 IL IL54342A patent/IL54342A/en unknown
- 1978-03-24 SU SU782595601A patent/SU1053755A3/en active
- 1978-03-24 JP JP3316578A patent/JPS53119898A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AT366685B (en) | 1982-04-26 |
| IL54342A (en) | 1981-02-27 |
| ES468133A1 (en) | 1980-06-16 |
| BE865267A (en) | 1978-09-25 |
| JPS53119898A (en) | 1978-10-19 |
| GB1596210A (en) | 1981-08-19 |
| FI780835A (en) | 1978-09-26 |
| AU3448378A (en) | 1979-09-27 |
| FI66375B (en) | 1984-06-29 |
| DK119778A (en) | 1978-09-26 |
| IL54342A0 (en) | 1978-06-15 |
| DE2810774A1 (en) | 1978-10-05 |
| AU520738B2 (en) | 1982-02-25 |
| IT1104183B (en) | 1985-10-21 |
| FI66375C (en) | 1984-10-10 |
| NZ186775A (en) | 1980-12-19 |
| PT67816A (en) | 1978-04-01 |
| NL7803031A (en) | 1978-09-27 |
| SE7803040L (en) | 1978-09-26 |
| CA1105009A (en) | 1981-07-14 |
| SU1053755A3 (en) | 1983-11-07 |
| IE46688B1 (en) | 1983-08-24 |
| IT7848557A0 (en) | 1978-03-23 |
| DK147072C (en) | 1984-09-10 |
| DK147072B (en) | 1984-04-02 |
| ZA781714B (en) | 1979-11-28 |
| ATA207078A (en) | 1981-09-15 |
| CH628049A5 (en) | 1982-02-15 |
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