CA1096863A - Improved process for preparing 9-substituted derivatives of guanine and adenine - Google Patents

Improved process for preparing 9-substituted derivatives of guanine and adenine

Info

Publication number
CA1096863A
CA1096863A CA285,592A CA285592A CA1096863A CA 1096863 A CA1096863 A CA 1096863A CA 285592 A CA285592 A CA 285592A CA 1096863 A CA1096863 A CA 1096863A
Authority
CA
Canada
Prior art keywords
hydroxy
adenine
formula
guanine
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA285,592A
Other languages
English (en)
French (fr)
Inventor
Howard J. Schaeffer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27109837&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA1096863(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US05/773,135 external-priority patent/US4146715A/en
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Application granted granted Critical
Publication of CA1096863A publication Critical patent/CA1096863A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CA285,592A 1976-08-27 1977-08-26 Improved process for preparing 9-substituted derivatives of guanine and adenine Expired CA1096863A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US71810576A 1976-08-27 1976-08-27
US718,105 1976-08-27
US05/773,135 US4146715A (en) 1975-08-27 1977-02-28 2-amido-9-(2-acyloxyethoxymethyl)hypoxanthines
US773,135 1977-02-28

Publications (1)

Publication Number Publication Date
CA1096863A true CA1096863A (en) 1981-03-03

Family

ID=27109837

Family Applications (2)

Application Number Title Priority Date Filing Date
CA285,592A Expired CA1096863A (en) 1976-08-27 1977-08-26 Improved process for preparing 9-substituted derivatives of guanine and adenine
CA354,538A Expired CA1096864A (en) 1976-08-27 1980-06-20 Intermediates for the preparation of derivatives of guanine and adenine

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA354,538A Expired CA1096864A (en) 1976-08-27 1980-06-20 Intermediates for the preparation of derivatives of guanine and adenine

Country Status (12)

Country Link
AT (1) AT357566B (de)
CA (2) CA1096863A (de)
CH (1) CH634843A5 (de)
CS (1) CS196384B2 (de)
DD (1) DD131856A6 (de)
DK (1) DK147857C (de)
FI (1) FI64160C (de)
GB (1) GB1567671A (de)
NL (1) NL7709458A (de)
NO (2) NO147186C (de)
SE (2) SE432764B (de)
YU (1) YU41079B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4880820A (en) * 1983-06-24 1989-11-14 Merck & Co., Inc. Guanine derivatives
IE842642L (en) * 1983-10-31 1985-04-30 Harvard College Purine Derivatives
US4918219A (en) * 1983-10-31 1990-04-17 Warner-Lambert Company Glycerine derivatives
YU45690B (sh) * 1984-12-22 1992-07-20 Krka Tovarna Zdraviln.Sol.O. Postopek za pripravo 9-(2-hidroksietoksimetil)-gvanina
DE3889248T2 (de) * 1987-05-04 1994-11-17 Kemijski Inst Verfahren zu Herstellung von Purinverbindungen.
CN1041632C (zh) * 1993-09-10 1999-01-13 里科达蒂化学药物公司 制备9－(2－羟基)－乙氧甲基鸟嘌呤的方法
DE19536164A1 (de) * 1995-09-28 1997-04-03 Boehringer Ingelheim Kg Verbessertes Verfahren zur Herstellung von 9-[(2-Hyroxyethoxy)methyl]guanin (Acyclovir)
IT1276126B1 (it) * 1995-11-14 1997-10-27 Archimica Spa Procedimento per la preparazine di 9-((2-idrossietossi)metil) guanina
WO1997024357A1 (en) * 1995-12-28 1997-07-10 Mallinckrodt Chemical, Inc. Process for synthesis and purification of a compound useful in the preparation of acyclovir

Also Published As

Publication number Publication date
DK380377A (da) 1978-02-28
SE8304549L (sv) 1983-08-23
SE8304549D0 (sv) 1983-08-23
CS196384B2 (en) 1980-03-31
YU41079B (en) 1986-12-31
NL7709458A (nl) 1978-03-01
SE447113B (sv) 1986-10-27
NO150119C (no) 1984-08-22
DK147857C (da) 1985-06-10
NO147186B (no) 1982-11-08
FI64160B (fi) 1983-06-30
AT357566B (de) 1980-07-25
DD131856A6 (de) 1978-07-26
FI64160C (fi) 1983-10-10
NO150119B (no) 1984-05-14
NO772959L (no) 1978-02-28
YU202277A (en) 1983-02-28
SE7709606L (sv) 1978-02-28
CH634843A5 (en) 1983-02-28
FI772548A (fi) 1978-02-28
NO822502L (no) 1978-02-28
NO147186C (no) 1983-02-16
CA1096864A (en) 1981-03-03
SE432764B (sv) 1984-04-16
DK147857B (da) 1984-12-24
GB1567671A (en) 1980-05-21
ATA620177A (de) 1979-12-15

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Legal Events

Date Code Title Description
MKEX Expiry