CA1096373A - Antibiotique, cephalosporine ureido substituee - Google Patents

Antibiotique, cephalosporine ureido substituee

Info

Publication number
CA1096373A
CA1096373A CA223,530A CA223530A CA1096373A CA 1096373 A CA1096373 A CA 1096373A CA 223530 A CA223530 A CA 223530A CA 1096373 A CA1096373 A CA 1096373A
Authority
CA
Canada
Prior art keywords
alpha
methyl
cephem
ylthiomethyl
carboxylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA223,530A
Other languages
English (en)
Inventor
David K. Herron
Robin D.G. Cooper
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of CA1096373A publication Critical patent/CA1096373A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • C07C273/1854—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas by reactions not involving the formation of the N-C(O)-N- moiety
    • C07C273/1863—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas by reactions not involving the formation of the N-C(O)-N- moiety from urea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • C07C273/1854—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas by reactions not involving the formation of the N-C(O)-N- moiety
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA223,530A 1974-04-01 1975-04-01 Antibiotique, cephalosporine ureido substituee Expired CA1096373A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45651674A 1974-04-01 1974-04-01
US456,516 1974-04-01

Publications (1)

Publication Number Publication Date
CA1096373A true CA1096373A (fr) 1981-02-24

Family

ID=23813076

Family Applications (1)

Application Number Title Priority Date Filing Date
CA223,530A Expired CA1096373A (fr) 1974-04-01 1975-04-01 Antibiotique, cephalosporine ureido substituee

Country Status (23)

Country Link
JP (1) JPS614837B2 (fr)
AR (1) AR210258A1 (fr)
AT (1) AT337896B (fr)
BE (1) BE827408A (fr)
BG (1) BG27376A3 (fr)
CA (1) CA1096373A (fr)
CH (1) CH627471A5 (fr)
CS (1) CS196261B2 (fr)
DD (1) DD118648A5 (fr)
DE (1) DE2514019A1 (fr)
DK (1) DK130375A (fr)
ES (1) ES436198A1 (fr)
FR (1) FR2265394B1 (fr)
GB (1) GB1504589A (fr)
HU (1) HU170816B (fr)
IE (1) IE42705B1 (fr)
IL (1) IL46956A (fr)
NL (1) NL7503883A (fr)
PH (1) PH13642A (fr)
PL (1) PL101400B1 (fr)
RO (1) RO67392A (fr)
SE (1) SE423392B (fr)
ZA (1) ZA752004B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4063019A (en) 1976-03-30 1977-12-13 E. R. Squibb & Sons, Inc. [[[(2,4-Dioxo-1-imidazolidinyl)amino]carbonyl]amino]-acetylcephalosporin derivatives
CN1069639C (zh) * 1998-06-19 2001-08-15 山东沂蒙新华制药厂 1－氯甲酰基－3－甲磺酰基咪唑烷酮的制备方法

Also Published As

Publication number Publication date
DE2514019A1 (de) 1975-10-02
AT337896B (de) 1977-07-25
CS196261B2 (en) 1980-03-31
GB1504589A (en) 1978-03-22
AR210258A1 (es) 1977-07-15
ATA247675A (de) 1976-11-15
CH627471A5 (en) 1982-01-15
DD118648A5 (fr) 1976-03-12
IE42705B1 (en) 1980-10-08
IL46956A0 (en) 1975-05-22
FR2265394A1 (fr) 1975-10-24
HU170816B (hu) 1977-09-28
PL101400B1 (pl) 1978-12-30
JPS614837B2 (fr) 1986-02-13
JPS50137995A (fr) 1975-11-01
BG27376A3 (en) 1979-10-12
ZA752004B (en) 1976-11-24
BE827408A (fr) 1975-10-01
IE42705L (en) 1975-10-01
SE423392B (sv) 1985-05-03
RO67392A (fr) 1981-04-30
AU7963775A (en) 1976-09-30
SE7503707L (fr) 1975-10-02
PH13642A (en) 1980-08-18
FR2265394B1 (fr) 1978-07-28
NL7503883A (nl) 1975-10-03
ES436198A1 (es) 1977-01-01
IL46956A (en) 1979-10-31
DK130375A (fr) 1975-10-02

Similar Documents

Publication Publication Date Title
US3641021A (en) 3 7-(ring-substituted) cephalosporin compounds
US4470983A (en) Cephalosporin derivatives
HU184799B (en) Process for producing 7-square bracket-bracket-2-aryl-bracket closed-2-hydroxy-imino-acetamido-sguare bracket closed-ceph-3-eme-4-carboxylic acid derivatives
GB1599722A (en) Cephalosporin derivatives
SU541438A3 (ru) Способ получени ацилуреидоцефалоспоринов или их солей или эфиров
SE453091B (sv) Nya cefalosporinderivat, forfarande for framstellning derav samt kompositioner derav
US5202315A (en) Cephalosporin compounds
US3956292A (en) 7-(α-FUROYLUREIDOARYL AND CYCLOHEXADIENYLACETAMIDO) CEPHALOSPORIN ANTIBIOTICS
US4147863A (en) 7-D-(-)-mandelamido-3-(1-methyl-1H-tetrazol-5-yl)vinyl-3-cephem-4-carboxylic acid
CA1096373A (fr) Antibiotique, cephalosporine ureido substituee
SE448239B (sv) Nya penicillinderivat och deras framstellning
US4492692A (en) Cephalosporin derivatives
US4224442A (en) 7-Ureido acetamido substituted cephalosporin antibiotics
US4388316A (en) Amino-substituted oxazole, oxadiazole and isoxazole-substituted cephalosporins
JPS6133836B2 (fr)
US5593985A (en) Cephalosporin compounds
US4061630A (en) 7-Substituted-ureido-3-carbamoyloxymethyl cephalosporin antibiotics
US4101656A (en) 7β-Acylamino-3-(alkanesulfonamidoalkyl substituted tetrazolylthiomethyl) cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them
US4093723A (en) 7-Acyl-3-(sulfonic acid and sulfamoyl substituted tetrazolyl thiomethyl) cephalosporins
US4959495A (en) Process for the preparation of intermediates used to produce aminothiazoloximino cephalosporins
KR790000945B1 (ko) 우레이도 치환 세팔로스포린 유도체의 제조방법
US3926957A (en) Penicillin antibiotics
US4159373A (en) 7-Acyl-3-(sulfonic acid and sulfamoyl substituted tetrazolyl thiomethyl) cephalosporins
SU584788A3 (ru) Способ получени уреидозамещенных цефалоспорановых соединений или их солей, или их эфиров
US4174323A (en) 1-(2-Sulfamidoethyl)-1,4-dihydro-5H-tetrazole-5-thione

Legal Events

Date Code Title Description
MKEX Expiry