CA1094551A - Diindole alkaloid and a process for the preparation thereof - Google Patents
Diindole alkaloid and a process for the preparation thereofInfo
- Publication number
- CA1094551A CA1094551A CA272,431A CA272431A CA1094551A CA 1094551 A CA1094551 A CA 1094551A CA 272431 A CA272431 A CA 272431A CA 1094551 A CA1094551 A CA 1094551A
- Authority
- CA
- Canada
- Prior art keywords
- deacetoxy
- vincristine
- oxidative
- formylation
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU76RI00000586A HU172183B (hu) | 1976-02-24 | 1976-02-24 | Spsosob poluchenija 4-dezacetoksi-vinkhristina i kislotodobavochnykh solejj |
| HURI-586 | 1976-02-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1094551A true CA1094551A (en) | 1981-01-27 |
Family
ID=11000995
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA272,431A Expired CA1094551A (en) | 1976-02-24 | 1977-02-23 | Diindole alkaloid and a process for the preparation thereof |
Country Status (15)
| Country | Link |
|---|---|
| JP (1) | JPS52102300A (cs) |
| AT (1) | AT353429B (cs) |
| AU (1) | AU506508B2 (cs) |
| BE (1) | BE851697A (cs) |
| CA (1) | CA1094551A (cs) |
| CH (1) | CH627185A5 (cs) |
| DE (1) | DE2706366A1 (cs) |
| DK (1) | DK142815B (cs) |
| FR (1) | FR2342295A1 (cs) |
| GB (1) | GB1525372A (cs) |
| HU (1) | HU172183B (cs) |
| IL (1) | IL51486A (cs) |
| NL (1) | NL7701948A (cs) |
| SE (1) | SE430694B (cs) |
| SU (1) | SU673174A3 (cs) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5891011A (ja) * | 1981-11-25 | 1983-05-30 | Toshiba Ceramics Co Ltd | α相含有率の高い窒化珪素粉末の製造方法 |
| CN112521408B (zh) * | 2020-12-16 | 2022-05-17 | 广州白云山汉方现代药业有限公司 | 一种双吲哚类生物碱化合物及其制备方法与应用 |
| CN114933604A (zh) * | 2021-12-10 | 2022-08-23 | 广州白云山汉方现代药业有限公司 | 一种长春新碱类手性化合物杂质及其制备方法与应用 |
-
1976
- 1976-02-24 HU HU76RI00000586A patent/HU172183B/hu unknown
-
1977
- 1977-02-08 SE SE7701377A patent/SE430694B/xx not_active IP Right Cessation
- 1977-02-09 AT AT84177A patent/AT353429B/de not_active IP Right Cessation
- 1977-02-10 CH CH162477A patent/CH627185A5/de not_active IP Right Cessation
- 1977-02-10 AU AU22173/77A patent/AU506508B2/en not_active Expired
- 1977-02-15 DE DE19772706366 patent/DE2706366A1/de not_active Withdrawn
- 1977-02-17 IL IL51486A patent/IL51486A/xx unknown
- 1977-02-22 SU SU772453504A patent/SU673174A3/ru active
- 1977-02-22 FR FR7705059A patent/FR2342295A1/fr active Granted
- 1977-02-22 BE BE175146A patent/BE851697A/xx not_active IP Right Cessation
- 1977-02-23 DK DK78777AA patent/DK142815B/da not_active IP Right Cessation
- 1977-02-23 GB GB7677/77A patent/GB1525372A/en not_active Expired
- 1977-02-23 JP JP1824577A patent/JPS52102300A/ja active Pending
- 1977-02-23 NL NL7701948A patent/NL7701948A/xx not_active Application Discontinuation
- 1977-02-23 CA CA272,431A patent/CA1094551A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| IL51486A0 (en) | 1977-04-29 |
| DK142815C (cs) | 1981-08-24 |
| SU673174A3 (ru) | 1979-07-05 |
| AT353429B (de) | 1979-11-12 |
| AU2217377A (en) | 1978-08-17 |
| AU506508B2 (en) | 1980-01-10 |
| SE430694B (sv) | 1983-12-05 |
| FR2342295B1 (cs) | 1980-09-05 |
| JPS52102300A (en) | 1977-08-27 |
| IL51486A (en) | 1979-10-31 |
| SE7701377L (sv) | 1977-08-25 |
| FR2342295A1 (fr) | 1977-09-23 |
| GB1525372A (en) | 1978-09-20 |
| CH627185A5 (en) | 1981-12-31 |
| DK78777A (cs) | 1977-08-25 |
| HU172183B (hu) | 1978-06-28 |
| NL7701948A (nl) | 1977-08-26 |
| DE2706366A1 (de) | 1977-08-25 |
| BE851697A (fr) | 1977-06-16 |
| DK142815B (da) | 1981-02-02 |
| ATA84177A (de) | 1979-04-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KOSUGE et al. | Studies on cardiac principle of aconite root | |
| Wani et al. | Plant antitumor agents. 28. Resolution of a key tricyclic synthon, 5'(RS)-1, 5-dioxo-5'-hydroxy-2'H, 5'H, 6'H-6'-oxopyrano [3', 4'-f]. delta. 6, 8-tetrahydroindolizine: total synthesis and antitumor activity of 20 (S)-and 20 (R)-camptothecin | |
| DE2415980C2 (cs) | ||
| BAsNET et al. | 2'-Hydroxymatteucinol, a new C-methyl flavanone derivative from Matteccia orientalis; potent hypoglycemic activity in streptozotocin (STZ)-induced diabetic rat | |
| CA1060003A (en) | N-trifluoroacetyladriamycin-14-alkanoates and therapeutic compositions containing same | |
| Jolad et al. | Cytotoxic agent from Penstemon deustus (Scrophulariaceae): isolation and stereochemistry of liriodendrin, a symmetrically substituted furofuranoid lignan diglucoside | |
| Mason et al. | Alkaloids of the Amaryllidaceae. IV. Crystalline Alkaloids of Ammocharis coranica (Ker-Gawl.) Herb., Brunsvigia rosea (Lam.) Hannibal and Two Crinum Species | |
| US4298525A (en) | Bis-indole-alkaloid | |
| Cohen et al. | Alkaline degradation product of cephradine | |
| CA1094551A (en) | Diindole alkaloid and a process for the preparation thereof | |
| Bhakuni et al. | The alkaloids of Stephania glabra | |
| US3969369A (en) | Bruceantin | |
| Ayer et al. | The alkaloids of Lycopodium alopecuroides L. | |
| US3944554A (en) | 4-Desacetoxy-3-hydroxyvinblastine | |
| Burnell et al. | Alkaloids of Tabernaemontana psychotrifolia HBK | |
| DE2558027A1 (de) | Amidderivate von vinblastin, leurosidin, leurocristin und damit verwandten dimeren alkaloiden sowie verfahren zu ihrer herstellung | |
| US4189432A (en) | N-formyl and N-desmethyl leurosine derivatives | |
| FI73436C (fi) | Foerfarande foer framstaellning av som laekemedel anvaendbara rifamyciner. | |
| US4164584A (en) | Anti-leukemic trichothecene epoxides | |
| Ferris et al. | Lythraceae alkaloids. VIII. Structure and stereochemistry of the biphenyl ether alkaloids from Decodon verticillatus | |
| El Moghazi et al. | Investigation of the alkaloidal constituents of Crinum bulbispermum | |
| RU2104707C1 (ru) | Способ получения вещества, обладающего противоопухолевой активностью, вещество, полученное этим способом, и фармацевтическая композиция на его основе | |
| Frank et al. | The composition of primycin | |
| WO1986001508A1 (en) | Opiate antagonists | |
| US4209443A (en) | Process for separating pharmaceutically active diindole alkaloids |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |