CA1088944A - Nitric ester of n-(2-hydroxyethyl)nicotinamide and a process for the preparation of same - Google Patents
Nitric ester of n-(2-hydroxyethyl)nicotinamide and a process for the preparation of sameInfo
- Publication number
- CA1088944A CA1088944A CA274,696A CA274696A CA1088944A CA 1088944 A CA1088944 A CA 1088944A CA 274696 A CA274696 A CA 274696A CA 1088944 A CA1088944 A CA 1088944A
- Authority
- CA
- Canada
- Prior art keywords
- compound
- formula
- carried out
- group
- reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP51036101A JPS5817463B2 (ja) | 1976-04-02 | 1976-04-02 | ニコチン酸アミド誘導体 |
JP36101/1976 | 1976-04-02 | ||
JP82458/1976 | 1976-07-13 | ||
JP8245876A JPS6052685B2 (ja) | 1976-07-13 | 1976-07-13 | 循環器疾患治療剤 |
JP8352276A JPS539775A (en) | 1976-07-15 | 1976-07-15 | Pyridine derivatives and their preparation |
JP83522/1976 | 1976-07-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA1088944A true CA1088944A (en) | 1980-11-04 |
Family
ID=27288973
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA274,696A Expired CA1088944A (en) | 1976-04-02 | 1977-03-24 | Nitric ester of n-(2-hydroxyethyl)nicotinamide and a process for the preparation of same |
Country Status (13)
Country | Link |
---|---|
AR (2) | AR217423A1 (da) |
AT (1) | AT360532B (da) |
AU (1) | AU509591B2 (da) |
CA (1) | CA1088944A (da) |
CH (1) | CH633535A5 (da) |
DE (1) | DE2714713C3 (da) |
DK (1) | DK145608C (da) |
ES (2) | ES457421A1 (da) |
FI (1) | FI66598C (da) |
FR (1) | FR2346334A1 (da) |
MX (1) | MX5534E (da) |
NL (2) | NL176674C (da) |
SE (1) | SE436029B (da) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU579431B2 (en) * | 1984-12-17 | 1988-11-24 | Chugai Seiyaku Kabushiki Kaisha | Method for production of stable nicorandil preparation |
WO2010000673A1 (en) * | 2008-07-01 | 2010-01-07 | Politechnika Lódzka | N'-nitroxyalkylnicotinamides for the treatment of cardiovascular diseases |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0223811A1 (en) * | 1985-05-22 | 1987-06-03 | Beecham Group Plc | Use of nicorandil or pinacidil for the treatment of peripheral vascular disease |
WO1989010757A1 (en) * | 1988-05-10 | 1989-11-16 | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemis | New ophthalmic preparation for treating glaucoma |
US4973565A (en) * | 1989-07-17 | 1990-11-27 | Corning Incorporated | Fluoroborosilicate glass and clad article |
ZA91291B (en) * | 1990-01-16 | 1991-09-25 | Hoechst Ag | Di(nitroxyalkyl)amides of pyridine-2,4-and-2,5-dicarboxylic acids,a process for the preparation thereof,and the use thereof |
US6417207B1 (en) | 1999-05-12 | 2002-07-09 | Nitromed, Inc. | Nitrosated and nitrosylated potassium channel activators, compositions and methods of use |
IT1403890B1 (it) | 2010-12-28 | 2013-11-08 | Procos Spa | Processo per la produzione di nicorandil |
-
1977
- 1977-03-23 DK DK128277A patent/DK145608C/da not_active IP Right Cessation
- 1977-03-23 AU AU23532/77A patent/AU509591B2/en not_active Expired
- 1977-03-24 CA CA274,696A patent/CA1088944A/en not_active Expired
- 1977-03-30 MX MX559377U patent/MX5534E/es unknown
- 1977-03-31 ES ES457421A patent/ES457421A1/es not_active Expired
- 1977-04-01 DE DE19772714713 patent/DE2714713C3/de not_active Expired
- 1977-04-01 CH CH415377A patent/CH633535A5/de not_active IP Right Cessation
- 1977-04-01 SE SE7703868A patent/SE436029B/xx not_active IP Right Cessation
- 1977-04-01 AR AR26709977A patent/AR217423A1/es active
- 1977-04-01 FI FI771024A patent/FI66598C/fi not_active IP Right Cessation
- 1977-04-04 NL NL7703624A patent/NL176674C/xx not_active IP Right Cessation
- 1977-04-04 AT AT235077A patent/AT360532B/de not_active IP Right Cessation
- 1977-04-04 FR FR7710119A patent/FR2346334A1/fr active Granted
-
1978
- 1978-02-20 AR AR27116278A patent/AR220907A1/es active
- 1978-03-31 ES ES468462A patent/ES468462A1/es not_active Expired
-
1993
- 1993-05-28 NL NL930042C patent/NL930042I2/nl unknown
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU579431B2 (en) * | 1984-12-17 | 1988-11-24 | Chugai Seiyaku Kabushiki Kaisha | Method for production of stable nicorandil preparation |
WO2010000673A1 (en) * | 2008-07-01 | 2010-01-07 | Politechnika Lódzka | N'-nitroxyalkylnicotinamides for the treatment of cardiovascular diseases |
Also Published As
Publication number | Publication date |
---|---|
NL7703624A (nl) | 1977-10-04 |
DK145608C (da) | 1983-07-11 |
AU2353277A (en) | 1978-09-28 |
NL176674C (nl) | 1985-05-17 |
FR2346334B1 (da) | 1980-02-01 |
AU509591B2 (en) | 1980-05-15 |
ATA235077A (de) | 1980-06-15 |
AR220907A1 (es) | 1980-12-15 |
FI66598C (fi) | 1984-11-12 |
DE2714713A1 (de) | 1977-10-20 |
FR2346334A1 (fr) | 1977-10-28 |
DE2714713C3 (de) | 1980-10-16 |
ES468462A1 (es) | 1979-10-01 |
SE436029B (sv) | 1984-11-05 |
DK128277A (da) | 1977-10-03 |
NL930042I2 (nl) | 1993-09-16 |
ES457421A1 (es) | 1978-11-16 |
FI66598B (fi) | 1984-07-31 |
FI771024A (da) | 1977-10-03 |
DE2714713B2 (de) | 1980-02-21 |
NL176674B (nl) | 1984-12-17 |
DK145608B (da) | 1982-12-27 |
AR217423A1 (es) | 1980-03-31 |
AT360532B (de) | 1981-01-12 |
SE7703868L (sv) | 1977-10-03 |
NL930042I1 (nl) | 1993-08-02 |
MX5534E (es) | 1983-09-27 |
CH633535A5 (en) | 1982-12-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MKEX | Expiry |