CA1085403A - 4-(9,10-dihydro-4h-benzo 4,5 cyclohepta 1,2- b thiophen-4-ylidene) piperidine compounds - Google Patents

4-(9,10-dihydro-4h-benzo 4,5 cyclohepta 1,2- b thiophen-4-ylidene) piperidine compounds

Info

Publication number
CA1085403A
CA1085403A CA255,311A CA255311A CA1085403A CA 1085403 A CA1085403 A CA 1085403A CA 255311 A CA255311 A CA 255311A CA 1085403 A CA1085403 A CA 1085403A
Authority
CA
Canada
Prior art keywords
compound
methyl
benzo
dihydro
thiophen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA255,311A
Other languages
English (en)
French (fr)
Inventor
Jean-Michel Bastian
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH817375A external-priority patent/CH615927A5/de
Priority claimed from CH817475A external-priority patent/CH613204A5/de
Application filed by Sandoz AG filed Critical Sandoz AG
Application granted granted Critical
Publication of CA1085403A publication Critical patent/CA1085403A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
CA255,311A 1975-06-24 1976-06-21 4-(9,10-dihydro-4h-benzo 4,5 cyclohepta 1,2- b thiophen-4-ylidene) piperidine compounds Expired CA1085403A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH817375A CH615927A5 (en) 1975-06-24 1975-06-24 Process for the preparation of novel benzocycloheptathiophene derivatives
CH817475A CH613204A5 (en) 1975-06-24 1975-06-24 Process for the preparation of novel benzocycloheptathiophene derivatives
CH8174/75 1975-06-24
CH8173/75 1975-06-24

Publications (1)

Publication Number Publication Date
CA1085403A true CA1085403A (en) 1980-09-09

Family

ID=25702907

Family Applications (1)

Application Number Title Priority Date Filing Date
CA255,311A Expired CA1085403A (en) 1975-06-24 1976-06-21 4-(9,10-dihydro-4h-benzo 4,5 cyclohepta 1,2- b thiophen-4-ylidene) piperidine compounds

Country Status (17)

Country Link
JP (1) JPS523075A (nl)
AU (1) AU508585B2 (nl)
CA (1) CA1085403A (nl)
DE (1) DE2626583A1 (nl)
DK (1) DK267976A (nl)
ES (1) ES449099A1 (nl)
FI (1) FI761721A (nl)
FR (1) FR2316949A1 (nl)
GB (1) GB1554427A (nl)
IE (1) IE43917B1 (nl)
IL (1) IL49862A (nl)
NL (1) NL7606700A (nl)
NO (1) NO762085L (nl)
NZ (1) NZ181236A (nl)
PH (1) PH14805A (nl)
PT (1) PT65264B (nl)
SE (1) SE7606877L (nl)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101932575B (zh) * 2008-01-30 2013-06-12 日本脏器制药株式会社 哌啶衍生物
WO2020063999A1 (en) * 2018-09-30 2020-04-02 National Institute Of Biological Sciences, Beijing Mono halogen or methyl-substituted 5-ht2b antagonists with increased activity

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS597963B2 (ja) * 1977-06-28 1984-02-22 沖電気工業株式会社 数値制御における円弧補間回路
DE3170504D1 (en) * 1980-09-02 1985-06-20 Sandoz Ag Piperidylidene derivatives, their production and pharmaceutical compositions containing them
JPS63205706A (ja) * 1987-02-23 1988-08-25 Yaskawa Electric Mfg Co Ltd 円弧加工制御方式
PL336007A1 (en) * 1997-04-03 2000-06-05 Bridge Pharma Chemical compounds of benzocycloheptathiophene
JP5083989B2 (ja) * 2008-11-20 2012-11-28 日本臓器製薬株式会社 ピペリジン誘導体を含有する医薬

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1437412A (fr) * 1963-12-19 1966-05-06 Sandoz Sa Nouveaux benzo-cyclohepta-thiophènes et leur préparation

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101932575B (zh) * 2008-01-30 2013-06-12 日本脏器制药株式会社 哌啶衍生物
WO2020063999A1 (en) * 2018-09-30 2020-04-02 National Institute Of Biological Sciences, Beijing Mono halogen or methyl-substituted 5-ht2b antagonists with increased activity
CN113227037A (zh) * 2018-09-30 2021-08-06 北京生命科学研究所 活性增加的单卤素或甲基取代的5-ht2b拮抗剂

Also Published As

Publication number Publication date
SE7606877L (sv) 1976-12-25
FR2316949B1 (nl) 1979-10-12
JPS523075A (en) 1977-01-11
ES449099A1 (es) 1978-03-01
NZ181236A (en) 1978-06-20
PT65264A (fr) 1976-07-01
FR2316949A1 (fr) 1977-02-04
IE43917B1 (en) 1981-07-01
AU1520376A (en) 1978-01-05
IL49862A (en) 1980-11-30
AU508585B2 (en) 1980-03-27
NO762085L (nl) 1976-12-28
FI761721A (nl) 1976-12-25
NL7606700A (nl) 1976-12-28
IL49862A0 (en) 1976-08-31
PT65264B (fr) 1978-03-24
IE43917L (en) 1976-12-24
GB1554427A (en) 1979-10-24
DE2626583A1 (de) 1977-01-13
DK267976A (da) 1976-12-25
PH14805A (en) 1981-12-14

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