IE43917L - 4-(9, 10-DIHYDRO-4H-BENZO [4,5] CYCLOHEPTA [1,2-b]¹THIOPHEN-4-YLIDENE) PIPERIDINES - Google Patents

4-(9, 10-DIHYDRO-4H-BENZO [4,5] CYCLOHEPTA [1,2-b]¹THIOPHEN-4-YLIDENE) PIPERIDINES

Info

Publication number
IE43917L
IE43917L IE761353A IE135376A IE43917L IE 43917 L IE43917 L IE 43917L IE 761353 A IE761353 A IE 761353A IE 135376 A IE135376 A IE 135376A IE 43917 L IE43917 L IE 43917L
Authority
IE
Ireland
Prior art keywords
ylidene
dihydro
benzo
1thiophen
cyclohepta
Prior art date
Application number
IE761353A
Other versions
IE43917B1 (en
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH817475A external-priority patent/CH613204A5/en
Priority claimed from CH817375A external-priority patent/CH615927A5/en
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of IE43917L publication Critical patent/IE43917L/en
Publication of IE43917B1 publication Critical patent/IE43917B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Case 100-4362 n4-(9,10-Dihydro-4H-Benzo4,5!Cyclcohepta1,2-b!Thiophen- 4-Ylidene)Piperidine Compounds This invention provides new compounds of formula I, (I) wherein R1 is hydrogen or alkyl, and R2 is alkyl, useful as analgesics. Case 100-4362 n4-(9,10-Dihydro-4H-Benzo¢4,5!Cyclcohepta¢1,2-b!Thiophen- 4-Ylidene)Piperidine Compounds This invention provides new compounds of formula I, (I) wherein R1 is hydrogen or alkyl, and R2 is alkyl, useful as analgesics. [CA1085403A]
IE1353/76A 1975-06-24 1976-06-22 4-(9,10-dihydro-4h-benzo/4,5/cyclohepta/1,2-b/thiophen-4-ylidine piperidines IE43917B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH817475A CH613204A5 (en) 1975-06-24 1975-06-24 Process for the preparation of novel benzocycloheptathiophene derivatives
CH817375A CH615927A5 (en) 1975-06-24 1975-06-24 Process for the preparation of novel benzocycloheptathiophene derivatives

Publications (2)

Publication Number Publication Date
IE43917L true IE43917L (en) 1976-12-24
IE43917B1 IE43917B1 (en) 1981-07-01

Family

ID=25702907

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1353/76A IE43917B1 (en) 1975-06-24 1976-06-22 4-(9,10-dihydro-4h-benzo/4,5/cyclohepta/1,2-b/thiophen-4-ylidine piperidines

Country Status (17)

Country Link
JP (1) JPS523075A (en)
AU (1) AU508585B2 (en)
CA (1) CA1085403A (en)
DE (1) DE2626583A1 (en)
DK (1) DK267976A (en)
ES (1) ES449099A1 (en)
FI (1) FI761721A (en)
FR (1) FR2316949A1 (en)
GB (1) GB1554427A (en)
IE (1) IE43917B1 (en)
IL (1) IL49862A (en)
NL (1) NL7606700A (en)
NO (1) NO762085L (en)
NZ (1) NZ181236A (en)
PH (1) PH14805A (en)
PT (1) PT65264B (en)
SE (1) SE7606877L (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS597963B2 (en) * 1977-06-28 1984-02-22 沖電気工業株式会社 Circular interpolation circuit in numerical control
DE3170504D1 (en) * 1980-09-02 1985-06-20 Sandoz Ag Piperidylidene derivatives, their production and pharmaceutical compositions containing them
JPS63205706A (en) * 1987-02-23 1988-08-25 Yaskawa Electric Mfg Co Ltd Control system for circular arc working
WO1998043640A1 (en) * 1997-04-03 1998-10-08 Bridge Pharma, Inc. Benzocycloheptathiophene compounds
MX2010008400A (en) 2008-01-30 2010-08-23 Nippon Zoki Pharmaceutical Co Piperidine derivative.
JP5083989B2 (en) * 2008-11-20 2012-11-28 日本臓器製薬株式会社 Medicaments containing piperidine derivatives
WO2020063999A1 (en) * 2018-09-30 2020-04-02 National Institute Of Biological Sciences, Beijing Mono halogen or methyl-substituted 5-ht2b antagonists with increased activity

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1437412A (en) * 1963-12-19 1966-05-06 Sandoz Sa New benzo-cyclohepta-thiophenes and their preparation

Also Published As

Publication number Publication date
JPS523075A (en) 1977-01-11
PH14805A (en) 1981-12-14
PT65264A (en) 1976-07-01
FI761721A (en) 1976-12-25
IL49862A0 (en) 1976-08-31
FR2316949A1 (en) 1977-02-04
SE7606877L (en) 1976-12-25
IE43917B1 (en) 1981-07-01
IL49862A (en) 1980-11-30
ES449099A1 (en) 1978-03-01
AU1520376A (en) 1978-01-05
NZ181236A (en) 1978-06-20
DK267976A (en) 1976-12-25
NO762085L (en) 1976-12-28
PT65264B (en) 1978-03-24
DE2626583A1 (en) 1977-01-13
GB1554427A (en) 1979-10-24
CA1085403A (en) 1980-09-09
NL7606700A (en) 1976-12-28
AU508585B2 (en) 1980-03-27
FR2316949B1 (en) 1979-10-12

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