CA1085293A - Toxoids derived from protease and elastase of pseudomonas aeruginosa and production thereof - Google Patents

Toxoids derived from protease and elastase of pseudomonas aeruginosa and production thereof

Info

Publication number
CA1085293A
CA1085293A CA270,134A CA270134A CA1085293A CA 1085293 A CA1085293 A CA 1085293A CA 270134 A CA270134 A CA 270134A CA 1085293 A CA1085293 A CA 1085293A
Authority
CA
Canada
Prior art keywords
protease
elastase
toxoid
acid
pseudomonas aeruginosa
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA270,134A
Other languages
English (en)
French (fr)
Inventor
Yuzuru Homma
Kazuyuki Morihara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP1083676A external-priority patent/JPS5296727A/ja
Priority claimed from JP1083776A external-priority patent/JPS5296728A/ja
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Application granted granted Critical
Publication of CA1085293A publication Critical patent/CA1085293A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6448—Elastases, e.g. pancreatic elastase (3.4.21.36); leukocyte elastase (3.4.31.37)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Gram-negative bacteria
    • C07K16/1214—Pseudomonadaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA270,134A 1976-02-05 1977-01-20 Toxoids derived from protease and elastase of pseudomonas aeruginosa and production thereof Expired CA1085293A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP1083676A JPS5296727A (en) 1976-02-05 1976-02-05 Toxoid of pseudomonas aeruginosa protease
JP10837/1976 1976-02-05
JP10836/1976 1976-02-05
JP1083776A JPS5296728A (en) 1976-02-05 1976-02-05 Toxoid of pseudomonas aeruginosa elastase

Publications (1)

Publication Number Publication Date
CA1085293A true CA1085293A (en) 1980-09-09

Family

ID=26346182

Family Applications (1)

Application Number Title Priority Date Filing Date
CA270,134A Expired CA1085293A (en) 1976-02-05 1977-01-20 Toxoids derived from protease and elastase of pseudomonas aeruginosa and production thereof

Country Status (6)

Country Link
US (1) US4160023A (enExample)
CA (1) CA1085293A (enExample)
CH (1) CH628679A5 (enExample)
DE (1) DE2704767A1 (enExample)
FR (1) FR2362154A1 (enExample)
SE (2) SE442269B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1256370A (en) * 1984-02-24 1989-06-27 Yuzuru Homma Toxoids of elastase of pseudomonas aeruginosa origin
US5233024A (en) * 1991-04-09 1993-08-03 The Brigham & Women's Hospital Anti-idiotypic monoclonal antibodies for mucoid pseudomonas aeruginosa, their preparation and use

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2528972A (en) * 1947-05-15 1950-11-07 Western Reserve University Prophylactic toxoid compound and method of making same
US3135662A (en) * 1961-01-05 1964-06-02 Burroughs Wellcome Co Diphtheria toxoid preparation and its production
US3658986A (en) * 1969-07-02 1972-04-25 Victor N Tompkins Immunization methods against toxic effects of bacterial infection
US3674863A (en) * 1969-12-08 1972-07-04 Parke Davis & Co Polyvalent immunizing agents and methods for their production
US3928565A (en) * 1971-10-19 1975-12-23 Yuzuru Homma Pharmaceutical preparation of pseudomonas aeruginosa bacterial component possessing anti-tumor and anti-infection properties
US3987164A (en) * 1970-10-20 1976-10-19 Yuzuru Homma Method for prevention of pseudomonas aeruginosa infections
DE2152112C3 (de) * 1970-10-20 1979-10-11 Yuzuru Homma Impfstoff gegen Pseudomonas aeruginosa
FR2180594A1 (en) * 1972-04-21 1973-11-30 Research Corp Reducing elastase - elaborating bacterial infection - using bacterial elastase as antigen
FR2227861B1 (enExample) * 1973-05-04 1976-07-02 Anvar
DE2340911A1 (de) * 1973-08-13 1975-05-07 Behringwerke Ag Tetanus-antigen und verfahren zu seiner herstellung
JPS51133489A (en) * 1975-05-14 1976-11-19 Tokyo Daigaku Process for producing microbial components of pseudomonas aeruginosa h aving antimicrobial and antitumor activities
JPS5296729A (en) * 1976-02-05 1977-08-13 Shionogi & Co Ltd Mixed vaccin for cyanomycosis

Also Published As

Publication number Publication date
FR2362154A1 (fr) 1978-03-17
SE7701037L (sv) 1977-08-06
DE2704767A1 (de) 1977-08-18
SE442269B (sv) 1985-12-16
DE2704767C2 (enExample) 1987-07-23
US4160023A (en) 1979-07-03
FR2362154B1 (enExample) 1983-04-29
CH628679A5 (de) 1982-03-15
SE8203674L (sv) 1982-06-14
SE442086B (sv) 1985-12-02

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Legal Events

Date Code Title Description
MKEX Expiry