FR2180594A1 - Reducing elastase - elaborating bacterial infection - using bacterial elastase as antigen - Google Patents

Reducing elastase - elaborating bacterial infection - using bacterial elastase as antigen

Info

Publication number
FR2180594A1
FR2180594A1 FR7214319A FR7214319A FR2180594A1 FR 2180594 A1 FR2180594 A1 FR 2180594A1 FR 7214319 A FR7214319 A FR 7214319A FR 7214319 A FR7214319 A FR 7214319A FR 2180594 A1 FR2180594 A1 FR 2180594A1
Authority
FR
France
Prior art keywords
elastase
bacterial
elaborating
antigen
reducing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7214319A
Other languages
French (fr)
Other versions
FR2180594B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Corp
Original Assignee
Research Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Corp filed Critical Research Corp
Priority to FR7214319A priority Critical patent/FR2180594A1/en
Publication of FR2180594A1 publication Critical patent/FR2180594A1/en
Application granted granted Critical
Publication of FR2180594B1 publication Critical patent/FR2180594B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6448—Elastases, e.g. pancreatic elastase (3.4.21.36); leukocyte elastase (3.4.31.37)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1214—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Pseudomonadaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The toxic effects of infection by elastase-elaborating bacteria are minimised by parenteral administration of sufficient purified bacterial elastase to elicit antibody formation. The bacteria is e.g., a Pseudomonas organism such as P.aeruginosa. Alternatively immune serum contg. the antibodies may be parenterally administered. The serum may be prepd. by prior parenteral administration of purified bacterial elastase to a donor animal.
FR7214319A 1972-04-21 1972-04-21 Reducing elastase - elaborating bacterial infection - using bacterial elastase as antigen Granted FR2180594A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7214319A FR2180594A1 (en) 1972-04-21 1972-04-21 Reducing elastase - elaborating bacterial infection - using bacterial elastase as antigen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7214319A FR2180594A1 (en) 1972-04-21 1972-04-21 Reducing elastase - elaborating bacterial infection - using bacterial elastase as antigen

Publications (2)

Publication Number Publication Date
FR2180594A1 true FR2180594A1 (en) 1973-11-30
FR2180594B1 FR2180594B1 (en) 1975-06-13

Family

ID=9097352

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7214319A Granted FR2180594A1 (en) 1972-04-21 1972-04-21 Reducing elastase - elaborating bacterial infection - using bacterial elastase as antigen

Country Status (1)

Country Link
FR (1) FR2180594A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2362154A1 (en) * 1976-02-05 1978-03-17 Shionogi & Co TOXOIDS DERIVED FROM PROTEASE FROM PSEUDOMONAS AERUGINOSA AND THEIR PRODUCTION PROCESS
FR2366305A1 (en) * 1976-02-05 1978-04-28 Shionogi & Co TOXOIDS DERIVED FROM ELASTASE FROM PSEUDOMONAS AERUGINOSA AND THEIR PRODUCTION PROCESS

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2362154A1 (en) * 1976-02-05 1978-03-17 Shionogi & Co TOXOIDS DERIVED FROM PROTEASE FROM PSEUDOMONAS AERUGINOSA AND THEIR PRODUCTION PROCESS
FR2366305A1 (en) * 1976-02-05 1978-04-28 Shionogi & Co TOXOIDS DERIVED FROM ELASTASE FROM PSEUDOMONAS AERUGINOSA AND THEIR PRODUCTION PROCESS

Also Published As

Publication number Publication date
FR2180594B1 (en) 1975-06-13

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Legal Events

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ST Notification of lapse