RU95104722A - Method of antibody preparing to diphtheria corynebacteria
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Method of antibody preparing to diphtheria corynebacteria
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Publication number
RU95104722A
RU95104722ARU95104722/14ARU95104722ARU95104722ARU 95104722 ARU95104722 ARU 95104722ARU 95104722/14 ARU95104722/14 ARU 95104722/14ARU 95104722 ARU95104722 ARU 95104722ARU 95104722 ARU95104722 ARU 95104722A
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Application filed by Иркутский государственный университет, Институт эпидемиологии и микробиологии ВСНЦ РАМНfiledCriticalИркутский государственный университет
Priority to RU95104722ApriorityCriticalpatent/RU2129014C1/en
Publication of RU95104722ApublicationCriticalpatent/RU95104722A/en
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Publication of RU2129014C1publicationCriticalpatent/RU2129014C1/en
FIELD: medicine, immunology, microbiology. SUBSTANCE: antibodies were raised using preparation "Kodivak". The known synthetic polyelectrolytes poly-5-vinyltetrazole and copolymer of 5-isopropenyltetrazole with 1-vinylpyrrolidone (2:1) at concentration 0.4-0.6 mg/ml were used as immunoadjuvants. Method can be used for preparing protective antibodies to bacteria in animals and for hyperimmune sera production. EFFECT: enhanced and prolonged antibody producing.
Claims (1)
Изобретение относится к медицине и может быть использовано для получения защитных антител к бактериям у животных и в производстве гипериммунных сывороток. С целью усиления и пролонгирования выработки антител к коринебактериям дифтерии под действием препарата "Кодивак" использованы в качестве иммуноадъювантов известные синтетические полиэлектролиты поли-5-винил-тетразол и сополимер 5-изопропенилтетразола с 1-винил-пирролидином (2:1) в концентрации 0,4 - 0,6 мг/мл.The invention relates to medicine and can be used to obtain protective antibodies to bacteria in animals and in the production of hyperimmune sera. In order to enhance and prolong the production of antibodies to diphtheria corynebacteria under the action of the Kodivak preparation, the known synthetic polyelectrolytes poly-5-vinyl-tetrazole and a copolymer of 5-isopropenyltetrazole with 1-vinyl-pyrrolidine (2: 1) at a concentration of 0, were used as immunoadjuvants 4 - 0.6 mg / ml.
RU95104722A1995-03-311995-03-31Method of preparing antibodies raised to diphtheria corynebacteria
RU2129014C1
(en)
HUMAN MONOCLONE ANTIBODIES AGAINST A BACTERY TOXIN AND THEIR PREPARATION, CONTINUOUS CELL LINES, PRODUCING ANTITOXIN ANTIBODIES, AND ANTIBODIES 'USES
Antibodies, mixture of antibodies, fab-fragment, strains of hybridoma cells, methods of construction of cell strains, method of struggle against virus, method of antigen level decrease, dna