RU95104722A - Method of antibody preparing to diphtheria corynebacteria - Google Patents

Method of antibody preparing to diphtheria corynebacteria

Info

Publication number
RU95104722A
RU95104722A RU95104722/14A RU95104722A RU95104722A RU 95104722 A RU95104722 A RU 95104722A RU 95104722/14 A RU95104722/14 A RU 95104722/14A RU 95104722 A RU95104722 A RU 95104722A RU 95104722 A RU95104722 A RU 95104722A
Authority
RU
Russia
Prior art keywords
antibodies
production
corynebacteria
diphtheria
antibody preparing
Prior art date
Application number
RU95104722/14A
Other languages
Russian (ru)
Other versions
RU2129014C1 (en
Inventor
В.В. Анненков
С.И. Лещук
В.А. Круглова
Е.А. Шмелева
С.М. Попкова
Original Assignee
Иркутский государственный университет
Институт эпидемиологии и микробиологии ВСНЦ РАМН
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Иркутский государственный университет, Институт эпидемиологии и микробиологии ВСНЦ РАМН filed Critical Иркутский государственный университет
Priority to RU95104722A priority Critical patent/RU2129014C1/en
Publication of RU95104722A publication Critical patent/RU95104722A/en
Application granted granted Critical
Publication of RU2129014C1 publication Critical patent/RU2129014C1/en

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Abstract

FIELD: medicine, immunology, microbiology. SUBSTANCE: antibodies were raised using preparation "Kodivak". The known synthetic polyelectrolytes poly-5-vinyltetrazole and copolymer of 5-isopropenyltetrazole with 1-vinylpyrrolidone (2:1) at concentration 0.4-0.6 mg/ml were used as immunoadjuvants. Method can be used for preparing protective antibodies to bacteria in animals and for hyperimmune sera production. EFFECT: enhanced and prolonged antibody producing.

Claims (1)

Изобретение относится к медицине и может быть использовано для получения защитных антител к бактериям у животных и в производстве гипериммунных сывороток. С целью усиления и пролонгирования выработки антител к коринебактериям дифтерии под действием препарата "Кодивак" использованы в качестве иммуноадъювантов известные синтетические полиэлектролиты поли-5-винил-тетразол и сополимер 5-изопропенилтетразола с 1-винил-пирролидином (2:1) в концентрации 0,4 - 0,6 мг/мл.The invention relates to medicine and can be used to obtain protective antibodies to bacteria in animals and in the production of hyperimmune sera. In order to enhance and prolong the production of antibodies to diphtheria corynebacteria under the action of the Kodivak preparation, the known synthetic polyelectrolytes poly-5-vinyl-tetrazole and a copolymer of 5-isopropenyltetrazole with 1-vinyl-pyrrolidine (2: 1) at a concentration of 0, were used as immunoadjuvants 4 - 0.6 mg / ml.
RU95104722A 1995-03-31 1995-03-31 Method of preparing antibodies raised to diphtheria corynebacteria RU2129014C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU95104722A RU2129014C1 (en) 1995-03-31 1995-03-31 Method of preparing antibodies raised to diphtheria corynebacteria

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU95104722A RU2129014C1 (en) 1995-03-31 1995-03-31 Method of preparing antibodies raised to diphtheria corynebacteria

Publications (2)

Publication Number Publication Date
RU95104722A true RU95104722A (en) 1996-12-20
RU2129014C1 RU2129014C1 (en) 1999-04-20

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
RU95104722A RU2129014C1 (en) 1995-03-31 1995-03-31 Method of preparing antibodies raised to diphtheria corynebacteria

Country Status (1)

Country Link
RU (1) RU2129014C1 (en)

Also Published As

Publication number Publication date
RU2129014C1 (en) 1999-04-20

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