CA1074327A - Anti-inflammatory imidazoles - Google Patents

Anti-inflammatory imidazoles

Info

Publication number
CA1074327A
CA1074327A CA258,690A CA258690A CA1074327A CA 1074327 A CA1074327 A CA 1074327A CA 258690 A CA258690 A CA 258690A CA 1074327 A CA1074327 A CA 1074327A
Authority
CA
Canada
Prior art keywords
alkyl
formula
compound
cf2cf2h
different
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA258,690A
Other languages
English (en)
French (fr)
Inventor
Thomas R. Sharpe
Saul C. Cherkofsky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EIDP Inc
Original Assignee
EI Du Pont de Nemours and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co
Application granted granted Critical
Publication of CA1074327A publication Critical patent/CA1074327A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CA258,690A 1975-08-11 1976-08-09 Anti-inflammatory imidazoles Expired CA1074327A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60365075A 1975-08-11 1975-08-11
US69128276A 1976-06-09 1976-06-09

Publications (1)

Publication Number Publication Date
CA1074327A true CA1074327A (en) 1980-03-25

Family

ID=27084480

Family Applications (1)

Application Number Title Priority Date Filing Date
CA258,690A Expired CA1074327A (en) 1975-08-11 1976-08-09 Anti-inflammatory imidazoles

Country Status (26)

Country Link
JP (1) JPS6011702B2 (fi)
AR (2) AR215591A1 (fi)
AU (1) AU508605B2 (fi)
CA (1) CA1074327A (fi)
CH (1) CH638791A5 (fi)
DD (1) DD126244A5 (fi)
DE (1) DE2635876A1 (fi)
DK (1) DK361376A (fi)
ES (2) ES450601A1 (fi)
FI (1) FI66177C (fi)
FR (1) FR2320745A1 (fi)
GB (1) GB1516908A (fi)
GR (1) GR61145B (fi)
HU (1) HU174707B (fi)
IE (1) IE44019B1 (fi)
IL (1) IL50230A (fi)
LU (1) LU75578A1 (fi)
MX (1) MX3932E (fi)
NL (1) NL7608915A (fi)
NO (1) NO146571C (fi)
NZ (1) NZ181731A (fi)
PH (1) PH11857A (fi)
PT (1) PT65464B (fi)
SE (1) SE428686B (fi)
SU (1) SU640662A3 (fi)
YU (1) YU198176A (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK16778A (da) * 1977-02-09 1978-08-10 Du Pont Imidazolderivater deres anvendelser og fremstilling
LU77703A1 (de) * 1977-07-07 1979-03-26 Ciba Geigy Ag Verfahren zur herstellung von bicyclischen thia-diaza-verbindungen
CY1302A (en) * 1978-04-11 1985-12-06 Ciba Geigy Ag Mercapto-imidazole derivatives,their preparation,their pharmaceutical compositions and applications
DE2823197A1 (de) 1978-05-24 1979-11-29 Schering Ag Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
US4308277A (en) * 1978-08-10 1981-12-29 Ciba-Geigy Corporation 2,4,5-Trisubstituted imidazolines and pharmaceutical compositions containing same
US4188397A (en) * 1978-09-22 1980-02-12 Smithkline Corporation 2,2-Alkyldiylbis(thio)bis(imidazoles)
US4215135A (en) * 1979-06-08 1980-07-29 E. I. Du Pont De Nemours And Company Antiinflammatory 2-substituted-1H-phenanthro[9,10-d]imidazoles
DE2856909A1 (de) * 1978-12-28 1980-07-17 Schering Ag Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
GB8907656D0 (en) * 1989-04-05 1989-05-17 May & Baker Ltd New compositions of matter
JP2002515915A (ja) * 1997-06-30 2002-05-28 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド 炎症性疾患の治療で有用な２−置換イミダゾール類
DE10222103A1 (de) * 2002-05-17 2003-11-27 Merckle Gmbh Chem Pharm Fabrik 2-Thio-substituierte Imidazolderivate und ihre Verwendung in der Pharmazie

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE688585A (fi) * 1965-10-21 1967-04-20
US3651080A (en) * 1969-11-07 1972-03-21 Ciba Geigy Corp Certain substituted 2-alkylmercaptoimidazole derivatives
US3636003A (en) * 1969-11-17 1972-01-18 Geigy Chem Corp Substituted 2-mercaptoimidazole derivatives
US3714179A (en) * 1970-09-08 1973-01-30 Searle & Co 1-alkyl-2-furfurylthioimidazoles and congeners
US3707475A (en) * 1970-11-16 1972-12-26 Pfizer Antiinflammatory imidazoles

Also Published As

Publication number Publication date
GB1516908A (en) 1978-07-05
NO762754L (fi) 1977-02-14
NO146571B (no) 1982-07-19
HU174707B (hu) 1980-03-28
DD126244A5 (fi) 1977-07-06
FR2320745A1 (fr) 1977-03-11
MX3932E (es) 1981-10-02
NL7608915A (nl) 1977-02-15
ES450601A1 (es) 1978-01-16
CH638791A5 (de) 1983-10-14
IL50230A0 (en) 1976-10-31
JPS6011702B2 (ja) 1985-03-27
DK361376A (da) 1977-02-12
FI66177B (fi) 1984-05-31
IE44019B1 (en) 1981-07-29
YU198176A (en) 1982-10-31
ES461193A1 (es) 1978-12-01
SE7607615L (sv) 1977-02-12
IE44019L (en) 1977-02-11
PH11857A (en) 1978-08-03
FR2320745B1 (fi) 1978-12-22
NZ181731A (en) 1978-11-13
JPS5223076A (en) 1977-02-21
IL50230A (en) 1979-07-25
FI762290A (fi) 1977-02-12
LU75578A1 (fi) 1978-04-13
AR215591A1 (es) 1979-10-31
AU1671176A (en) 1978-02-16
PT65464B (en) 1978-08-02
GR61145B (en) 1978-09-27
SE428686B (sv) 1983-07-18
PT65464A (en) 1976-09-01
AR218054A1 (es) 1980-05-15
NO146571C (no) 1982-10-27
FI66177C (fi) 1984-09-10
DE2635876A1 (de) 1977-03-03
AU508605B2 (en) 1980-03-27
SU640662A3 (ru) 1978-12-30

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Legal Events

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