CA1069514A - Substituted 4-phenyl-imidazolines, their acid addition salts and process for their production - Google Patents

Substituted 4-phenyl-imidazolines, their acid addition salts and process for their production

Info

Publication number
CA1069514A
CA1069514A CA254,445A CA254445A CA1069514A CA 1069514 A CA1069514 A CA 1069514A CA 254445 A CA254445 A CA 254445A CA 1069514 A CA1069514 A CA 1069514A
Authority
CA
Canada
Prior art keywords
methyl
imidazoline
diethylamino
bis
hydrochloride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA254,445A
Other languages
English (en)
French (fr)
Inventor
Helmut Stahle
Werner Kummer
Richard Reichl
Walter Haarmann
Herbert Koppe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim GmbH
Original Assignee
Boehringer Ingelheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim GmbH filed Critical Boehringer Ingelheim GmbH
Application granted granted Critical
Publication of CA1069514A publication Critical patent/CA1069514A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/48—Nitrogen atoms not forming part of a nitro radical with acyclic hydrocarbon or substituted acyclic hydrocarbon radicals, attached to said nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CA254,445A 1975-06-10 1976-06-09 Substituted 4-phenyl-imidazolines, their acid addition salts and process for their production Expired CA1069514A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2525725A DE2525725C3 (de) 1975-06-10 1975-06-10 Basisch substituierte 2-AIkylamino-4-phenyl-imidazoline, deren Säureadditionssalze, Verfahren zu ihrer Herstellung und deren Verwendung

Publications (1)

Publication Number Publication Date
CA1069514A true CA1069514A (en) 1980-01-08

Family

ID=5948681

Family Applications (1)

Application Number Title Priority Date Filing Date
CA254,445A Expired CA1069514A (en) 1975-06-10 1976-06-09 Substituted 4-phenyl-imidazolines, their acid addition salts and process for their production

Country Status (23)

Country Link
US (1) US4058616A (show.php)
JP (1) JPS603066B2 (show.php)
AT (1) AT351020B (show.php)
AU (1) AU498253B2 (show.php)
BE (1) BE842768A (show.php)
CA (1) CA1069514A (show.php)
CH (1) CH622785A5 (show.php)
DE (1) DE2525725C3 (show.php)
DK (1) DK142172C (show.php)
ES (1) ES448696A1 (show.php)
FI (1) FI62069C (show.php)
FR (1) FR2313926A1 (show.php)
GB (1) GB1481948A (show.php)
GR (1) GR60041B (show.php)
IE (1) IE43793B1 (show.php)
IL (1) IL49747A (show.php)
LU (1) LU75114A1 (show.php)
MX (1) MX3153E (show.php)
NL (1) NL7606266A (show.php)
NO (1) NO144214C (show.php)
PT (1) PT65201B (show.php)
SE (1) SE422936B (show.php)
ZA (1) ZA763422B (show.php)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4105765A (en) * 1975-06-10 1978-08-08 Boehringer Ingelheim Gmbh 2-(N-(1,3-diamino-isopropyl)-amino)-4-phenyl-2-imidazolines and salts thereof
US4288591A (en) * 1979-02-06 1981-09-08 A. H. Robins Company, Inc. 4-Substituted 2-iminoimidazolidine compounds
US4288447A (en) * 1979-02-06 1981-09-08 A. H. Robins Company, Inc. Antihyperglycemic 4-substituted 2-iminoimidazolidine compositions
US4647557A (en) * 1982-12-28 1987-03-03 Gerard Moinet Novel heterocyclic derivatives bearing an amino radical, processes for their production and the pharmaceutical compositions containing them

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2586844A (en) * 1947-10-21 1952-02-26 Ayerst Mckenna & Harrison Preparation of delta2-1, 3-diazacycloalkenes
FR2081571B1 (show.php) * 1970-03-12 1973-04-06 Synthelabo

Also Published As

Publication number Publication date
PT65201A (de) 1976-07-01
IL49747A0 (en) 1976-08-31
NO144214C (no) 1981-07-15
IE43793B1 (en) 1981-06-03
AU1477076A (en) 1977-12-15
DK142172B (da) 1980-09-15
AU498253B2 (en) 1979-02-22
JPS603066B2 (ja) 1985-01-25
ZA763422B (en) 1978-02-22
GB1481948A (en) 1977-08-03
ATA366676A (de) 1978-12-15
LU75114A1 (show.php) 1978-01-18
IL49747A (en) 1979-03-12
DE2525725B2 (de) 1979-01-18
FR2313926A1 (fr) 1977-01-07
FI62069B (fi) 1982-07-30
BE842768A (fr) 1976-12-09
IE43793L (en) 1976-12-10
PT65201B (de) 1978-05-08
NO761970L (show.php) 1976-12-13
DK255976A (da) 1976-12-11
DE2525725A1 (de) 1976-12-30
SE7606497L (sv) 1976-12-11
FI761423A7 (show.php) 1976-12-11
AT351020B (de) 1979-07-10
JPS51149273A (en) 1976-12-22
ES448696A1 (es) 1977-07-01
GR60041B (en) 1978-04-01
MX3153E (es) 1980-05-12
NO144214B (no) 1981-04-06
FI62069C (fi) 1982-11-10
US4058616A (en) 1977-11-15
NL7606266A (nl) 1976-12-14
DE2525725C3 (de) 1979-09-13
SE422936B (sv) 1982-04-05
FR2313926B1 (show.php) 1978-10-20
DK142172C (da) 1981-02-09
CH622785A5 (show.php) 1981-04-30

Similar Documents

Publication Publication Date Title
US4663325A (en) 1-(2,3,4-tri-methoxybenzyl)-4[bis(4-fluorophenyl)methyl] piperazines are useful for treating cerebrovascular disease
AU2003215591B2 (en) Dihydropteridinones, method for the production and use thereof in the form of drugs
AU2002337047B2 (en) Novel dihydropteridinones, method for producing the same and the use thereof as medicaments
DE102004029784A1 (de) Neue 2-Benzylaminodihydropteridinone, Verfahren zur deren Herstellung und deren Verwendung als Arzneimittel
US4873331A (en) Noradamantyl-carboxylic acid piperazinoalkyl esters
CH660484A5 (de) In 1-stellung durch einen heterocyclischen rest substituierte 4-((2,5-pyrrolidindion-1-yl)alkyl)piperazin-verbindungen.
US4182887A (en) 3-Amino-4-phenyl-1H-pyrazolo[3,4-b]pyridines and salts thereof
CH649995A5 (de) Piperazinderivate, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten.
DE68910451T2 (de) 1,4-benzoxazin- und 1,4-benzothiazin-derivate und verfahren zu deren herstellung.
US4388237A (en) 6(1-Piperazinyl), piperidino and (1(homopiperazinyl)11-cyanomethylene morphanthridines
HU195509B (en) Process for producing pyridinyl-piperazine derivatives and pharmaceutical compositions containing them as active agents
US4588725A (en) 2-piperazinyl-quinazoline derivatives and pharmaceutical compositions containing them
US3301855A (en) Derivatives of 4-nu-(2-nu, nu-dimethylaminolower alkyl)-amino quinazoline
US5252567A (en) Diazine derivatives
JPH0441149B2 (show.php)
IE43793B1 (en) 2-(disubstituted amino)-4-phenyl-imidazolines and their use in pharmaceutical compositions
US4252806A (en) Triazoloquinolones
EP0270692A1 (en) Antiarrhythmic agent
US4112092A (en) 1-Naphthylmethyl-4-(thiazolyl-2)-piperazines
US3426017A (en) Sulfonylurea compounds
US5071849A (en) Dihydropyrimidothiazine derivatives
US3793322A (en) 1,4-disubstituted piperazines
US3898224A (en) 1,6,7,8-Tetrahydro-4-oxo-4H-pyrido {8 1,2-A{9 pyrimidine-9-carboalkoxy compounds
US3822267A (en) 1 substituted 4 piperazino cycloalkylthiazoles
JPS6130588A (ja) ベンゾ〔ｃ〕〔１，８〕ナフチリジン、その製造方法及びその使用、並びにこれらの化合物を含有する調製剤

Legal Events

Date Code Title Description
MKEX Expiry