CA1068694A - Process for preparing 2(1h)-quinazolinone derivatives - Google Patents

Process for preparing 2(1h)-quinazolinone derivatives

Info

Publication number
CA1068694A
CA1068694A CA267,562A CA267562A CA1068694A CA 1068694 A CA1068694 A CA 1068694A CA 267562 A CA267562 A CA 267562A CA 1068694 A CA1068694 A CA 1068694A
Authority
CA
Canada
Prior art keywords
phenyl
methyl
methoxy
quinazolinone
sulfur
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA267,562A
Other languages
English (en)
French (fr)
Inventor
Michihiro Yamamoto
Shigenari Katayama
Hisao Yamamoto
Masao Koshiba
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Application granted granted Critical
Publication of CA1068694A publication Critical patent/CA1068694A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C07D239/80—Oxygen atoms
    • C07D239/82—Oxygen atoms with an aryl radical attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CA267,562A 1975-12-11 1976-12-09 Process for preparing 2(1h)-quinazolinone derivatives Expired CA1068694A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP50148279A JPS5271483A (en) 1975-12-11 1975-12-11 Synthesis of 2(1h)-quinazolinone derivatives

Publications (1)

Publication Number Publication Date
CA1068694A true CA1068694A (en) 1979-12-25

Family

ID=15449201

Family Applications (1)

Application Number Title Priority Date Filing Date
CA267,562A Expired CA1068694A (en) 1975-12-11 1976-12-09 Process for preparing 2(1h)-quinazolinone derivatives

Country Status (13)

Country Link
US (1) US4387223A (enExample)
JP (1) JPS5271483A (enExample)
AT (1) AT352737B (enExample)
CA (1) CA1068694A (enExample)
CH (1) CH602667A5 (enExample)
DE (1) DE2656156A1 (enExample)
DK (1) DK138989B (enExample)
FR (1) FR2376142A1 (enExample)
GB (1) GB1510270A (enExample)
HU (1) HU173530B (enExample)
MX (1) MX3930E (enExample)
NL (1) NL7613307A (enExample)
SE (1) SE422578B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT374469B (de) * 1978-12-07 1984-04-25 Ortho Pharma Corp Verfahren zur herstellung von neuen substituierten chinazolinen und ihren salzen
US4617392A (en) * 1983-09-29 1986-10-14 Ortho Pharmaceutical Corporation 4-alkyl-5,6-methylenedioxy-2-1[H]-quinazolinones useful as cardiotonic agents
US4666913A (en) * 1985-11-22 1987-05-19 William H. Rorer, Inc. Hydroxy and aminothiazolyl-benzodiazinone compounds, cardiotonic compositions including the same, and their uses
AR038658A1 (es) * 2001-06-15 2005-01-26 Novartis Ag Derivados de 4-aril-2(1h) quinazolinona y 4-aril-quinazolina 2-sustituidas, un proceso para su preparacion, composiciones farmaceuticas y el uso de dichos derivados para la preparacion de un medicamento
EP1394242A3 (en) * 2002-08-07 2004-04-21 Rohm And Haas Company Cyclic thioureas and their use as additives for lubricating oils
AU2007231842B2 (en) * 2002-12-23 2011-04-14 Novartis Ag Derivatives of aryl-quinazoline/aryl-2-amino-phenyl methanone which promote the release of parathyroid hormone
GB0230015D0 (en) * 2002-12-23 2003-01-29 Novartis Ag Organic compounds
JP4533391B2 (ja) * 2004-01-16 2010-09-01 エフ．ホフマン−ラ ロシュ アーゲー 中枢神経系疾患の処置のための５−ヒドロキシトリプタミンレセプター（５−ｈｔ）のモジュレーターとしての、１−ベンジル−５−ピペラジン−１−イル−３，４−ジヒドロ−１ｈ−キナゾリン−２−オン誘導体、ならびにそれぞれの１ｈ−ベンゾ（１，２，６）チアジアジン−２，２−ジオキシドおよび１，４−ジヒドロベンゾ（ｄ）（１，３）オキサジン−２−オン誘導体
US8058469B2 (en) * 2008-11-03 2011-11-15 Sabic Innovative Plastics Ip B.V. Method for making carbamates, ureas and isocyanates
US9834525B2 (en) 2014-02-04 2017-12-05 University Of Tennessee Research Foundation Inhibitors of paxillin function and related compositions and methods

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE93775C (enExample) *
US3560501A (en) * 1966-09-15 1971-02-02 Ciba Geigy Corp Process for making dihydroquinazolines
US3509149A (en) * 1968-05-10 1970-04-28 Searle & Co Aryl and aralkyl 3,4-dihydro-2-(1h)-quinazolinones
FR2012061A1 (en) 1969-06-30 1970-03-13 Sandoz Sa Quinazolinone derivs - with antiphlogistic props
CH522673A (de) * 1969-11-27 1972-05-15 Ciba Geigy Ag Verfahren zur Herstellung von neuen Diglycidylderivaten N-heterocyclischer Verbindungen, und ihre Anwendung
US3748331A (en) * 1971-05-06 1973-07-24 Sandoz Ag 1,4-disubstituted-methylenedioxy -2-(1h)-quinazolinones and quinazolinthiones
BE785937A (fr) 1971-07-08 1973-01-08 Sandoz Sa Nouveaux derives de la quinazoline, leur preparation et leur application comme medicaments
US3937705A (en) * 1972-03-09 1976-02-10 Sandoz, Inc. 1-isopropyl-7-methyl-4-(p-fluorophenyl)-2(1h)-quinazolinone
JPS5251379A (en) * 1975-10-24 1977-04-25 Sumitomo Chem Co Ltd Preparation 3,4-dihydro-2(1h)-quinazoline derivates
JPS5291885A (en) * 1976-01-23 1977-08-02 Sumitomo Chem Co Ltd 3,4-dihydro-2(1h)-quinazolinone derivatives

Also Published As

Publication number Publication date
NL7613307A (nl) 1977-06-14
HU173530B (hu) 1979-06-28
DK138989C (enExample) 1979-05-14
US4387223A (en) 1983-06-07
AT352737B (de) 1979-10-10
ATA915976A (de) 1979-03-15
FR2376142A1 (fr) 1978-07-28
DK553076A (enExample) 1977-06-12
CH602667A5 (enExample) 1978-07-31
FR2376142B1 (enExample) 1979-04-20
MX3930E (es) 1981-10-01
DE2656156A1 (de) 1977-06-23
DK138989B (da) 1978-11-27
GB1510270A (en) 1978-05-10
AU2016476A (en) 1977-11-10
JPS5271483A (en) 1977-06-14
SE7613839L (sv) 1977-06-12
SE422578B (sv) 1982-03-15

Similar Documents

Publication Publication Date Title
CA1068694A (en) Process for preparing 2(1h)-quinazolinone derivatives
AU2003231162B2 (en) Process for the preparation of 7-substituted-3-quinoline and 3-quinol-4-one carbonitriles
JP3390741B2 (ja) プロテインチロシンキナーゼ阻害剤としての二環式ヘテロ芳香族化合物
EP0287951B1 (en) 7-Piperazinyl- or 7-Morpholino-4-oxo-quinoline-3-carboxylic acid derivatives, their preparation and their use as antimicrobial agents
EP0237781B1 (en) Phenyl and heterocyclic tetrahydropyridyl and piperazinyl alkoxy-benzheterocyclic compounds as antipsychotic agents
US5679678A (en) Thienithiazine derivatives
AU654581B2 (en) 2-substituted saccharin derivative proteolytic enzyme inhibitors
KR100435247B1 (ko) 나프탈렌유도체,그의제조방법,및그의중간체
CA1211440A (en) Carboxamido-derivatives of 5h-1,3,4-thiadiazolo ¬3, 2-a| pyrimidines and process for their preparation
NO324563B1 (no) Substituerte 3-cyanokinoliner, anvendelse av slike forbindelser til fremstilling av farmasoytiske preparater, farmasoytiske preparater omfattende slike forbindelser samt fremgangsmate for fremstilling av slike.
US4738970A (en) Benzimidazolyl-thio-tetrahydroquinolines and anti-peptic ulcer compositions containing the same
KR20010033405A (ko) 4-히드록시퀴놀린-3-카르복스아미드 및 히드라지드항바이러스제
RO112868B1 (ro) Heteroarilamine, procedee pentru prepararea acestora, compozitie farmaceutica si metoda de tratament
CA2142471A1 (en) Benzopyran and benzoxazine derivatives
EP2379543A2 (en) Thiazolyl-benzimidazoles
CA2195444A1 (en) Thiopyridyl compounds for controlling helicobacter bacteria
CA1311756C (en) Triazine derivatives
US4202895A (en) 1-Polyhaloalkyl-2(1H)-quinazolinone derivatives
AU759629B2 (en) Pyrimidin-aminomethyl-pyridine derivatives, their preparation and their use in the control of helicobacter bacteria
EP0276826B1 (en) 2-alkylsulfinyl-4 (3h)-quinazolinone derivatives, processes for their preparation and pharmaceutical compositions
FI80458C (fi) Foerfarande foer framstaellning av . terapeutiskt anvaendbara tiazolo/3,2-a/bensimidazoler och 2,3-dihydroanaloger daerav.
EP0239129B1 (en) Hydroquinoline compounds, compositions containing same and processes for preparing same
Besson et al. Imidazoquinolinethiones from 8-aminoquinolines by a novel peri-participation
Joshi et al. Synthesis of some thiadiazoles, selenadiazoles and spiroheterocyclic compounds from their 2, 2-dimethyl-benzopyran precursors
US5008390A (en) Compounds for preparing 6-phenyl-2,3-dihydroimidazo[2,1-b]-thiazoles and corresponding thiazines