CA1064942A - Pyroglutamy compounds having antidepressive activity and process for their manufacture - Google Patents
Pyroglutamy compounds having antidepressive activity and process for their manufactureInfo
- Publication number
- CA1064942A CA1064942A CA227,255A CA227255A CA1064942A CA 1064942 A CA1064942 A CA 1064942A CA 227255 A CA227255 A CA 227255A CA 1064942 A CA1064942 A CA 1064942A
- Authority
- CA
- Canada
- Prior art keywords
- formula
- acid
- pyroglutamyl
- compound
- derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
- C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06173—Dipeptides with the first amino acid being heterocyclic and Glp-amino acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2423390A DE2423390A1 (de) | 1974-05-14 | 1974-05-14 | Pyroglutamylverbindungen mit antidepressiver wirkung und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1064942A true CA1064942A (en) | 1979-10-23 |
Family
ID=5915523
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA227,255A Expired CA1064942A (en) | 1974-05-14 | 1975-05-13 | Pyroglutamy compounds having antidepressive activity and process for their manufacture |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS50157362A (da) |
| AT (2) | AT352707B (da) |
| BE (1) | BE829059A (da) |
| CA (1) | CA1064942A (da) |
| CH (2) | CH612180A5 (da) |
| DE (1) | DE2423390A1 (da) |
| DK (1) | DK209575A (da) |
| FR (1) | FR2270866B1 (da) |
| GB (1) | GB1472154A (da) |
| IE (1) | IE41145B1 (da) |
| IL (1) | IL47258A (da) |
| LU (1) | LU72450A1 (da) |
| NL (1) | NL7505473A (da) |
| SE (1) | SE405113B (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996004244A1 (en) * | 1994-08-05 | 1996-02-15 | Warwick International Group Limited | Bleach activators |
| CN1282319A (zh) * | 1997-10-09 | 2001-01-31 | 小野药品工业株式会社 | 氨基丁酸衍生物 |
| RU2232578C1 (ru) * | 2003-04-10 | 2004-07-20 | Ахапкина Валентина Ивановна | Вещество, обладающее антидепрессивной активностью |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5220996B2 (da) * | 1972-01-14 | 1977-06-07 | ||
| JPS5015793B2 (da) * | 1972-06-07 | 1975-06-07 |
-
1974
- 1974-05-14 DE DE2423390A patent/DE2423390A1/de not_active Withdrawn
-
1975
- 1975-05-08 IL IL47258A patent/IL47258A/xx unknown
- 1975-05-09 NL NL7505473A patent/NL7505473A/xx not_active Application Discontinuation
- 1975-05-12 LU LU72450A patent/LU72450A1/xx unknown
- 1975-05-12 GB GB1984075A patent/GB1472154A/en not_active Expired
- 1975-05-12 CH CH608075A patent/CH612180A5/xx not_active IP Right Cessation
- 1975-05-12 CH CH85079A patent/CH613689A5/xx not_active IP Right Cessation
- 1975-05-13 DK DK209575A patent/DK209575A/da not_active Application Discontinuation
- 1975-05-13 AT AT364875A patent/AT352707B/de not_active IP Right Cessation
- 1975-05-13 IE IE1069/75A patent/IE41145B1/xx unknown
- 1975-05-13 CA CA227,255A patent/CA1064942A/en not_active Expired
- 1975-05-14 JP JP50056232A patent/JPS50157362A/ja active Pending
- 1975-05-14 SE SE7505546A patent/SE405113B/xx unknown
- 1975-05-14 BE BE156337A patent/BE829059A/xx not_active IP Right Cessation
- 1975-05-14 FR FR7515026A patent/FR2270866B1/fr not_active Expired
-
1979
- 1979-01-08 AT AT0013179A patent/AT364875B/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IL47258A0 (en) | 1975-07-28 |
| DE2423390A1 (de) | 1975-12-04 |
| IE41145B1 (en) | 1979-10-24 |
| LU72450A1 (da) | 1977-02-09 |
| IE41145L (en) | 1975-11-14 |
| CH613689A5 (en) | 1979-10-15 |
| DK209575A (da) | 1975-11-15 |
| CH612180A5 (en) | 1979-07-13 |
| BE829059A (fr) | 1975-11-14 |
| NL7505473A (nl) | 1975-11-18 |
| AT352707B (de) | 1979-10-10 |
| FR2270866A1 (da) | 1975-12-12 |
| GB1472154A (en) | 1977-05-04 |
| FR2270866B1 (da) | 1978-08-04 |
| AT364875B (de) | 1979-03-15 |
| ATA364875A (de) | 1979-03-15 |
| SE7505546L (sv) | 1975-11-17 |
| SE405113B (sv) | 1978-11-20 |
| JPS50157362A (da) | 1975-12-19 |
| IL47258A (en) | 1978-07-31 |
| ATA13179A (de) | 1981-04-15 |
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