CA1064933A - Benzoic acids, their derivatives and process for preparing them - Google Patents
Benzoic acids, their derivatives and process for preparing themInfo
- Publication number
- CA1064933A CA1064933A CA242,877A CA242877A CA1064933A CA 1064933 A CA1064933 A CA 1064933A CA 242877 A CA242877 A CA 242877A CA 1064933 A CA1064933 A CA 1064933A
- Authority
- CA
- Canada
- Prior art keywords
- benzoic acid
- chloro
- ethyl
- methoxy
- benzamido
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Quinoline Compounds (AREA)
- Furan Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2500157A DE2500157C2 (de) | 1975-01-03 | 1975-01-03 | N-Acyl-4-(2-aminoäthyl)-benzoesäuren, deren Salze und Ester, Verfahren zu deren Herstellung und deren Verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1064933A true CA1064933A (en) | 1979-10-23 |
Family
ID=5935941
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA242,877A Expired CA1064933A (en) | 1975-01-03 | 1975-12-31 | Benzoic acids, their derivatives and process for preparing them |
Country Status (24)
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2517229A1 (de) * | 1975-04-18 | 1976-10-28 | Boehringer Mannheim Gmbh | Phenylalkylcarbonsaeure-derivate und verfahren zu ihrer herstellung |
| DE2532420A1 (de) * | 1975-07-19 | 1977-02-03 | Boehringer Mannheim Gmbh | Phenylessigsaeure-derivate und verfahren zu ihrer herstellung |
| DE2639935A1 (de) * | 1976-09-04 | 1978-03-09 | Hoechst Ag | Benzoesaeuren und verfahren zu ihrer herstellung |
| DE2706977A1 (de) * | 1977-02-18 | 1978-08-24 | Hoechst Ag | Benzoesaeuren und deren derivate sowie verfahren zu ihrer herstellung |
| LU79008A1 (de) * | 1978-02-03 | 1979-09-06 | Byk Gulden Lomberg Chem Fab | W-(n-alkyl-n-benzoyl-amino)-phenylalkansaeuren,ihre verwendung und herstellung sowie sie enthaltende arzneimittel |
| DE3063878D1 (en) * | 1979-07-13 | 1983-07-28 | Thomae Gmbh Dr K | Derivatives of carboxylic acids, their preparation and medicaments containing them |
| EP0029320B1 (en) * | 1979-11-15 | 1985-07-10 | Beecham Group Plc | Secondary ethanol amines, their preparation and their use in pharmaceutical compositions |
| DE3100535A1 (de) * | 1981-01-10 | 1982-08-12 | Dr. Karl Thomae Gmbh, 7950 Biberach | "neue carbonsaeure-derivate, ihre herstellung und ihre verwendung als arzneimittel" |
| DE3211934A1 (de) * | 1982-03-31 | 1983-10-13 | Hoechst Ag, 6230 Frankfurt | Salicylsaeurederivate, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen und ihre verwendung |
| PT77219B (fr) * | 1982-08-24 | 1986-02-04 | May & Baker Ltd | Procede de preparation des derives de la benzamide |
| LU86258A1 (fr) * | 1986-01-21 | 1987-09-03 | Rech Dermatologiques C I R D S | Composes benzamido aromatique,leur procede de preparation et leur utilisation en medecine humaine ou veterinaire et en cosmetique |
| GB8708833D0 (en) * | 1987-04-13 | 1987-05-20 | Lilly S A E | Organic compounds |
| GB8823041D0 (en) * | 1988-09-30 | 1988-11-09 | Lilly Sa | Organic compounds & their use as pharmaceuticals |
| GB8823042D0 (en) * | 1988-09-30 | 1988-11-09 | Lilly Sa | Organic compounds & their use as pharmaceuticals |
| GB8823040D0 (en) * | 1988-09-30 | 1988-11-09 | Lilly Sa | Organic compounds & their use as pharmaceuticals |
| EP0478787B1 (en) * | 1990-03-20 | 1994-12-21 | Shionogi & Co., Ltd. | Novel process for producing benzoic acid derivative |
| US6344213B1 (en) | 1996-03-29 | 2002-02-05 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| CA2057324A1 (en) * | 1990-12-18 | 1992-06-19 | Lora Louise Fitch | Benzamide and sulfonamide hypoglycemic agents |
| US6916489B2 (en) * | 1992-06-15 | 2005-07-12 | Emisphere Technologies, Inc. | Active agent transport systems |
| US20010003001A1 (en) * | 1993-04-22 | 2001-06-07 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| US6001347A (en) | 1995-03-31 | 1999-12-14 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| US6358504B1 (en) | 1997-02-07 | 2002-03-19 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| US6194458B1 (en) * | 1998-10-30 | 2001-02-27 | Merck & Co., Inc. | Benzamide potassium channel inhibitors |
| DE60017888T2 (de) * | 1999-04-05 | 2006-01-19 | Emisphere Technologies, Inc. | Dinatrium-salze, monohydrate und ethanol-solvate |
| ES2298168T3 (es) * | 1999-12-16 | 2008-05-16 | Emisphere Technologies, Inc. | Compuestos y composiciones para suministrar agentes activos. |
| TWI282786B (en) * | 2000-04-28 | 2007-06-21 | Nihon Nohyaku Co Ltd | A process for preparing 2-halogenobenzoic acids |
| US7157487B2 (en) * | 2000-12-28 | 2007-01-02 | Daiichi Pharmaceutical Co., Ltd. | Vla-4 inhibitors |
| JP4676884B2 (ja) | 2003-07-24 | 2011-04-27 | 第一三共株式会社 | シクロヘキサンカルボン酸類 |
| BRPI0414130B8 (pt) | 2003-09-03 | 2021-05-25 | Askat Inc | compostos de fenilamida ou piridilamida, seu uso e composições farmacêuticas que os compreendem. |
| JP2005209106A (ja) * | 2004-01-26 | 2005-08-04 | Nec Corp | 携帯通信端末、受信メール管理方法、プログラムおよび記録媒体 |
| BRPI0510598A (pt) * | 2004-05-04 | 2007-11-20 | Pfizer | compostos de amida de aril ou heteroaril substituìdos |
| EP1960350B1 (en) * | 2005-11-22 | 2015-08-19 | Bayer Intellectual Property GmbH | New n-(1-methyl-2phenylethyl)benzamide derivatives |
| JP5244091B2 (ja) | 2006-04-24 | 2013-07-24 | メルク カナダ インコーポレイテッド | Ｅｐ４受容体アンタゴニストとしてのインドールアミド誘導体 |
| WO2012003145A2 (en) | 2010-07-02 | 2012-01-05 | Allergan, Inc. | Therapeutic agents for ocular hypertension |
| US9714238B2 (en) | 2010-07-02 | 2017-07-25 | Allergan, Inc. | Therapeutic agents for ocular hypertension |
| JO3296B1 (ar) | 2012-06-29 | 2018-09-16 | Lilly Co Eli | مركبات فينوكسي إيثيل بيبريدين |
| TWI636046B (zh) | 2013-05-17 | 2018-09-21 | 美國禮來大藥廠 | 苯氧基乙基二氫－１ｈ－異喹啉化合物 |
| HUE035698T2 (en) | 2013-12-17 | 2018-05-28 | Lilly Co Eli | Phenoxyethyl ring amine derivatives and their activity as EP4 receptor modulator |
| CA3036245C (en) * | 2016-09-13 | 2021-07-20 | Arbutus Biopharma Corporation | Substituted chromane-8-carboxamide compounds and analogues thereof, and methods using same |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3100226A (en) * | 1959-10-16 | 1963-08-06 | Amchem Prod | 2,5 dichloro-3 acylaminobenzoic acids |
| US3536753A (en) * | 1969-05-27 | 1970-10-27 | Geigy Chem Corp | O-(substituted benzamido)phenylacetic acids |
| US3636094A (en) * | 1969-07-25 | 1972-01-18 | Searle & Co | Norbornanecarboxylic acid amides of anthranilic acid |
| FR2088225A1 (en) * | 1970-05-29 | 1972-01-07 | Ugine Kuhlmann | Substd salicylanilides - having antiuric props |
| US3855285A (en) * | 1971-06-21 | 1974-12-17 | Pfizer | Acylmethylthio-trifluoromethyl-benzoic acids |
| DE2230383C3 (de) * | 1971-10-01 | 1981-12-03 | Boehringer Mannheim Gmbh, 6800 Mannheim | Phenoxyalkylcarbonsäurederivate und Verfahren zur Herstellung derselben |
| DE2320387A1 (de) * | 1973-04-21 | 1974-10-31 | Boehringer Mannheim Gmbh | Phenoxyalkylcarbonsaeurederivate und verfahren zur herstellung derselben |
-
1975
- 1975-01-03 DE DE2500157A patent/DE2500157C2/de not_active Expired
- 1975-12-27 ES ES443910A patent/ES443910A1/es not_active Expired
- 1975-12-28 IL IL48749A patent/IL48749A/xx unknown
- 1975-12-29 EG EG75768A patent/EG12067A/xx active
- 1975-12-29 NL NL7515129A patent/NL7515129A/xx not_active Application Discontinuation
- 1975-12-30 CH CH1689175A patent/CH619209A5/de not_active IP Right Cessation
- 1975-12-31 AU AU87964/75A patent/AU501010B2/en not_active Expired
- 1975-12-31 FR FR7540257A patent/FR2296407A1/fr active Granted
- 1975-12-31 CA CA242,877A patent/CA1064933A/en not_active Expired
- 1975-12-31 FI FI753721A patent/FI753721A/fi not_active Application Discontinuation
- 1975-12-31 IT IT30935/75A patent/IT1052091B/it active
-
1976
- 1976-01-02 HU HU76HO1869A patent/HU174325B/hu unknown
- 1976-01-02 US US05/646,378 patent/US4221815A/en not_active Expired - Lifetime
- 1976-01-02 NO NO760003A patent/NO760003L/no unknown
- 1976-01-02 LU LU74129A patent/LU74129A1/xx unknown
- 1976-01-02 ZA ZA00760007A patent/ZA767B/xx unknown
- 1976-01-02 AT AT1876A patent/AT347922B/de not_active IP Right Cessation
- 1976-01-02 PT PT64670A patent/PT64670B/pt unknown
- 1976-01-02 IE IE2/76A patent/IE42391B1/en unknown
- 1976-01-02 SE SE7600012A patent/SE7600012L/xx not_active Application Discontinuation
- 1976-01-02 DK DK276*BA patent/DK276A/da unknown
- 1976-01-05 BE BE163313A patent/BE837311A/xx not_active IP Right Cessation
- 1976-01-05 JP JP51000731A patent/JPS51131846A/ja active Pending
- 1976-01-05 GB GB145/76A patent/GB1538482A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NO760003L (US06262066-20010717-C00424.png) | 1976-07-06 |
| CH619209A5 (US06262066-20010717-C00424.png) | 1980-09-15 |
| IE42391L (en) | 1976-07-03 |
| ES443910A1 (es) | 1977-04-16 |
| LU74129A1 (US06262066-20010717-C00424.png) | 1976-11-11 |
| IE42391B1 (en) | 1980-07-30 |
| NL7515129A (nl) | 1976-07-06 |
| ATA1876A (de) | 1978-06-15 |
| IL48749A0 (en) | 1976-02-29 |
| GB1538482A (en) | 1979-01-17 |
| AU8796475A (en) | 1977-07-07 |
| FI753721A (US06262066-20010717-C00424.png) | 1976-07-04 |
| DK276A (da) | 1976-07-04 |
| AU501010B2 (en) | 1979-06-07 |
| PT64670B (fr) | 1977-08-08 |
| DE2500157A1 (de) | 1976-07-22 |
| EG12067A (en) | 1978-12-31 |
| BE837311A (fr) | 1976-07-05 |
| IT1052091B (it) | 1981-06-20 |
| PT64670A (fr) | 1976-05-01 |
| AT347922B (de) | 1979-01-25 |
| FR2296407B1 (US06262066-20010717-C00424.png) | 1979-06-29 |
| IL48749A (en) | 1979-09-30 |
| DE2500157C2 (de) | 1983-09-15 |
| JPS51131846A (en) | 1976-11-16 |
| US4221815A (en) | 1980-09-09 |
| FR2296407A1 (fr) | 1976-07-30 |
| SE7600012L (sv) | 1976-07-05 |
| ZA767B (en) | 1976-12-29 |
| HU174325B (hu) | 1979-12-28 |
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