CA1055866A - Antitumor antibiotics aclacinomycins from streptomyces galilaeus - Google Patents
Antitumor antibiotics aclacinomycins from streptomyces galilaeusInfo
- Publication number
- CA1055866A CA1055866A CA232,210A CA232210A CA1055866A CA 1055866 A CA1055866 A CA 1055866A CA 232210 A CA232210 A CA 232210A CA 1055866 A CA1055866 A CA 1055866A
- Authority
- CA
- Canada
- Prior art keywords
- aclacinomycin
- acid
- group
- nutrient medium
- cultured
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP49086390A JPS5134915B2 (US20040232935A1-20041125-M00001.png) | 1974-07-27 | 1974-07-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1055866A true CA1055866A (en) | 1979-06-05 |
Family
ID=13885534
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA232,210A Expired CA1055866A (en) | 1974-07-27 | 1975-07-25 | Antitumor antibiotics aclacinomycins from streptomyces galilaeus |
Country Status (18)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111378008A (zh) * | 2020-03-02 | 2020-07-07 | 中国科学院南海海洋研究所 | 脂肽类化合物Totopotensamides及其制备方法和应用 |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS52136159A (en) * | 1976-04-07 | 1977-11-14 | Microbial Chem Res Found | Anti/malignanttumor containing the same as active ingredients |
| US4204038A (en) * | 1976-04-07 | 1980-05-20 | Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai | Process for preparing antibiotics MA 144-M1 and MA 144-M2 |
| US4039736A (en) * | 1976-04-15 | 1977-08-02 | Bristol-Myers Company | Antibiotic compounds marcellomycin and musettamycin |
| JPS5323961A (en) * | 1976-08-16 | 1978-03-06 | Microbial Chem Res Found | Antitumors |
| US4192915A (en) * | 1976-08-16 | 1980-03-11 | Bristol-Myers Company | Anthracycline glycosides from streptomyces |
| NL176004C (nl) * | 1976-10-05 | 1985-02-01 | Microbial Chem Res Found | Werkwijze ter bereiding van geneesmiddelen met antitumorwerking op basis van anthracycline glycosiden en werkwijze ter bereiding van daartoe dienende anthracycline glycosiden. |
| US4209588A (en) * | 1976-10-05 | 1980-06-24 | Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai | Process for producing new antitumor anthracycline antibiotics |
| EP0003664B1 (en) * | 1978-02-08 | 1982-02-17 | Imperial Chemical Industries Plc | Alkanolamine derivatives, process for their preparation and pharmaceutical compositions containing them |
| JPS5650105Y2 (US20040232935A1-20041125-M00001.png) * | 1978-03-01 | 1981-11-24 | ||
| ZA802929B (en) * | 1979-05-22 | 1981-05-27 | Hoffmann La Roche | Novel tetracyclic compounds and process for the preparation thereof |
| JPS6023679B2 (ja) * | 1979-07-13 | 1985-06-08 | メルシャン株式会社 | ロドマイシン群抗生物質とその製造法 |
| EP0030255B1 (en) * | 1979-09-07 | 1986-01-29 | Sanraku Incorporated | 2-hydroxyaclacinomycin a, pharmaceutical composition containing it; 2-hydroxyaclavinone and fermentative process for preparing same |
| JPS57163393A (en) * | 1981-03-27 | 1982-10-07 | Microbial Chem Res Found | Novel anthracyclin derivative and its preparation |
| JPS5874694A (ja) * | 1981-10-29 | 1983-05-06 | Sanraku Inc | アントラサイクリン誘導体 |
| US4472571A (en) * | 1981-12-28 | 1984-09-18 | Hoffmann-La Roche Inc. | Optically active anthracycline glycosides A and B |
| US4405713A (en) * | 1981-12-28 | 1983-09-20 | Hoffmann-La Roche Inc. | Process for the preparation of optically active anthracycline glycosides A and B |
| IT1155446B (it) * | 1982-12-23 | 1987-01-28 | Erba Farmitalia | Procedimento per la purificazione di glucosidi antraciclinonici mediante adsobimento selettivo su resine |
| JPS6028916A (ja) * | 1983-07-13 | 1985-02-14 | Yamanouchi Pharmaceut Co Ltd | アクラルビシンまたはその塩酸塩の油性組成物 |
| US4863739A (en) * | 1987-05-19 | 1989-09-05 | Board Of Regents, The University Of Texas System | Liposome compositions of anthracycline derivatives |
| AU608415B2 (en) * | 1988-01-19 | 1991-03-28 | University Of Texas System, The | Esters of 3'-deaminodoxorubicin, liposomal compositions thereof |
| US4977084A (en) * | 1989-02-16 | 1990-12-11 | Board Of Trustees Operating Michigan State University | Production, isolation, and identification of novel antifungal compounds |
| US5013549A (en) * | 1989-02-16 | 1991-05-07 | Board Of Trustees Operating Michigan State University | Production, isolation, and identification of novel antifungal compounds |
| US5066585A (en) * | 1990-07-09 | 1991-11-19 | Board Of Trustees Operating Michigan State University | Method of inhibiting fungus using novel antifungal compounds |
| KR970000591B1 (ko) * | 1993-09-03 | 1997-01-14 | 동국제약 주식회사 | 신균주 스트렙토마이세스 라벤도폴리아 DKRS 및 이를 이용한 아클라시노마이신 A, B, Y 및 아글리콘(Aglycone)의 제조방법 |
| US20050208037A1 (en) * | 2003-10-21 | 2005-09-22 | Board Of Regents, The University Of Texas System | Thioredoxin increases redox-cycling of anticancer agents thereby sensitizes cancer cells to apoptosis |
| WO2014048379A1 (zh) | 2012-09-28 | 2014-04-03 | 杭州本生药业有限公司 | 治疗肿瘤的组合药物及其应用 |
-
1974
- 1974-07-27 JP JP49086390A patent/JPS5134915B2/ja not_active Expired
-
1975
- 1975-07-07 GB GB28465/75A patent/GB1491266A/en not_active Expired
- 1975-07-11 DK DK317075AA patent/DK141761B/da not_active IP Right Cessation
- 1975-07-15 ZA ZA00754555A patent/ZA754555B/xx unknown
- 1975-07-16 US US05/596,682 patent/US3988315A/en not_active Expired - Lifetime
- 1975-07-16 FR FR7522258A patent/FR2279413A1/fr active Granted
- 1975-07-21 DE DE2532568A patent/DE2532568C3/de not_active Expired
- 1975-07-23 IE IE1654/75A patent/IE42751B1/en unknown
- 1975-07-24 ES ES439747A patent/ES439747A1/es not_active Expired
- 1975-07-24 SE SE7508450A patent/SE434648B/xx not_active IP Right Cessation
- 1975-07-24 YU YU1884/75A patent/YU37188B/xx unknown
- 1975-07-25 HU HU75ZA00000385A patent/HU172209B/hu unknown
- 1975-07-25 BE BE158601A patent/BE831726A/xx not_active IP Right Cessation
- 1975-07-25 NL NLAANVRAGE7508878,A patent/NL170754C/xx not_active IP Right Cessation
- 1975-07-25 NO NO752639A patent/NO144064C/no unknown
- 1975-07-25 FI FI752142A patent/FI54496C/fi not_active IP Right Cessation
- 1975-07-25 CA CA232,210A patent/CA1055866A/en not_active Expired
- 1975-07-25 LU LU73063A patent/LU73063A1/xx unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111378008A (zh) * | 2020-03-02 | 2020-07-07 | 中国科学院南海海洋研究所 | 脂肽类化合物Totopotensamides及其制备方法和应用 |
| CN111378008B (zh) * | 2020-03-02 | 2022-04-12 | 中国科学院南海海洋研究所 | 脂肽类化合物Totopotensamides及其制备方法和应用 |
Also Published As
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