CA1032538A - Antiviral, substituted, 1,3-dimethyl-1 h-pyrazolo (3,4b) quinolines - Google Patents

Antiviral, substituted, 1,3-dimethyl-1 h-pyrazolo (3,4b) quinolines

Info

Publication number
CA1032538A
CA1032538A CA210,304A CA210304A CA1032538A CA 1032538 A CA1032538 A CA 1032538A CA 210304 A CA210304 A CA 210304A CA 1032538 A CA1032538 A CA 1032538A
Authority
CA
Canada
Prior art keywords
quinolines
pyrazolo
antiviral
dimethyl
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA210,304A
Other languages
English (en)
French (fr)
Other versions
CA210304S (en
Inventor
George M. Luke
Paul Siminoff
Ronnie R. Crenshaw
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of CA1032538A publication Critical patent/CA1032538A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/20—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 4
    • C07D265/22—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Fodder In General (AREA)
CA210,304A 1973-10-01 1974-09-30 Antiviral, substituted, 1,3-dimethyl-1 h-pyrazolo (3,4b) quinolines Expired CA1032538A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/402,657 US4013665A (en) 1973-10-01 1973-10-01 Antiviral, substituted 1,3-dimethyl-1h-pyrazolo(3,4b)quinolines

Publications (1)

Publication Number Publication Date
CA1032538A true CA1032538A (en) 1978-06-06

Family

ID=23592812

Family Applications (1)

Application Number Title Priority Date Filing Date
CA210,304A Expired CA1032538A (en) 1973-10-01 1974-09-30 Antiviral, substituted, 1,3-dimethyl-1 h-pyrazolo (3,4b) quinolines

Country Status (19)

Country Link
US (1) US4013665A (no)
JP (1) JPS582948B2 (no)
BE (1) BE820400A (no)
CA (1) CA1032538A (no)
CH (3) CH621552A5 (no)
CY (1) CY1087A (no)
DE (1) DE2446821A1 (no)
DK (1) DK516274A (no)
ES (1) ES430554A1 (no)
FI (1) FI57414C (no)
FR (1) FR2245369B1 (no)
GB (1) GB1488692A (no)
HK (1) HK59380A (no)
KE (1) KE3086A (no)
MY (1) MY8100219A (no)
NL (1) NL7412959A (no)
NO (1) NO143223C (no)
SE (1) SE419760B (no)
ZA (1) ZA746138B (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA848968B (en) * 1983-11-18 1986-06-25 Riker Laboratories Inc 1h-imidazo(4,5-c)quinolines and 1h-imidazo(4,5-c)quinolin-4-amines
IL73534A (en) * 1983-11-18 1990-12-23 Riker Laboratories Inc 1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds
US5332734A (en) * 1991-04-10 1994-07-26 Japan Tobacco, Incorporated Oxazinone derivative
US5608067A (en) * 1993-12-09 1997-03-04 Afonso; Adriano 4-substituted pyrazoloquinoline derivatives
US5506236A (en) * 1994-04-28 1996-04-09 Schering Corporation 4-substituted pyrazoloquinoline derivatives
US5786480A (en) * 1994-04-28 1998-07-28 Schering Corporation 4-substituted pyrazoloquinoline derivatives
US5614530A (en) * 1995-03-10 1997-03-25 Sterling Winthrop Inc. Substituted N-arylmethyl and heterocyclmethyl-1H-pyrazolo[3,4-b]quinolin-4-amines and compositions and methods of use thereof
US6008226A (en) * 1995-03-10 1999-12-28 Sanofi-Synthelabo Substituted N-arylmethyl and heterocylylmethyl-1H-pyrazolo[3,4-b]quinolin-4-amines and compositions and methods of use thereof
US5488055A (en) * 1995-03-10 1996-01-30 Sanofi Winthrop Inc. Substituted N-cycloalkylmethyl-1H-pyrazolo(3,4-b)quinolin-4 amines and compositions and methods of use thereof
US7084156B2 (en) * 2001-11-27 2006-08-01 Merck & Co., Inc. 2-Aminoquinoline compounds
WO2003045920A1 (en) * 2001-11-27 2003-06-05 Merck & Co., Inc. 4-aminoquinoline compounds
US8080560B2 (en) * 2004-12-17 2011-12-20 3M Innovative Properties Company Immune response modifier formulations containing oleic acid and methods
US8889154B2 (en) 2005-09-15 2014-11-18 Medicis Pharmaceutical Corporation Packaging for 1-(2-methylpropyl)-1H-imidazo[4,5-c] quinolin-4-amine-containing formulation
WO2008010963A2 (en) * 2006-07-18 2008-01-24 3M Innovative Properties Company Immune response modifier formulations
WO2008016475A2 (en) * 2006-07-31 2008-02-07 3M Innovative Properties Company Immune response modifier compositions and methods
WO2010062559A1 (en) * 2008-10-28 2010-06-03 Schering Corporation Substituted pyrazoloquinolines and derivatives thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1152421B (de) * 1961-03-21 1963-08-08 Bayer Ag Verfahren zur Herstellung von 4-Hydroxy-pyrazolo[3, 4-b]chinolinen
DE1445719A1 (de) * 1961-03-21 1969-01-09 Bayer Ag Verfahren zur Herstellung von 4-Chlor- oder 4-Brom-pyrazolo[3,4-]chinolinen
DE1186867B (de) * 1961-05-03 1965-02-11 Bayer Ag Verfahren zur Herstellung von heterocyclischen Verbindungen
DE1222885B (de) * 1962-05-25 1966-08-18 Bayer Ag Optische Aufhellungsmittel
US3600393A (en) * 1969-03-03 1971-08-17 Aldrich Chem Co Inc Dialkylamino alkylamino pyrazolo (3,4b) quinolines
JPS4826797A (no) * 1971-08-07 1973-04-09
US3790576A (en) * 1972-03-20 1974-02-05 Parke Davis & Co 9 substituted 4,9-dihydro-1,3,4,4-tetraalkyl-1h-pyrazolo(3,4-b)quinolines

Also Published As

Publication number Publication date
FR2245369A1 (no) 1975-04-25
NL7412959A (nl) 1975-04-03
FR2245369B1 (no) 1978-07-28
CY1087A (en) 1980-12-27
CH621552A5 (no) 1981-02-13
FI57414C (fi) 1980-08-11
GB1488692A (en) 1977-10-12
JPS5059396A (no) 1975-05-22
NO143223B (no) 1980-09-22
US4013665A (en) 1977-03-22
KE3086A (en) 1980-11-07
NO143223C (no) 1981-01-02
ES430554A1 (es) 1977-07-01
ZA746138B (en) 1975-10-29
NO743528L (no) 1975-04-28
CH622793A5 (no) 1981-04-30
DE2446821A1 (de) 1975-04-10
BE820400A (fr) 1975-03-26
AU7379874A (en) 1976-04-01
JPS582948B2 (ja) 1983-01-19
SE419760B (sv) 1981-08-24
CH619712A5 (no) 1980-10-15
HK59380A (en) 1980-10-31
SE7412275L (no) 1975-04-02
MY8100219A (en) 1981-12-31
FI57414B (fi) 1980-04-30
DK516274A (no) 1975-06-30
USB402657I5 (no) 1976-04-06
FI281574A (no) 1975-04-02

Similar Documents

Publication Publication Date Title
CA989843A (en) 2-alkyl-3-acyl-pyrazolo(1,5-a) pyridines
AU513469B2 (en) Pyrido (2, 1, -b) - quinazoline derivatives
AU500196B2 (en) Pyrido / 2, 1-6 / quinazolinones
CA1032538A (en) Antiviral, substituted, 1,3-dimethyl-1 h-pyrazolo (3,4b) quinolines
AU475718B2 (en) 9-(SUBSTITUTED AMINO) IMIDAZO [4,5-f] QUINOLINES
AU473160B2 (en) 9-(SUBSTITUTED AMINO) IMIDAZO [4,5-f] QUINOLINE
HK4080A (en) Imidazo(4,5-b)pyridines
ZA745673B (en) S-triazol(1,5-a) pyridine derivative
CA1010032A (en) Imidazo (3,4-d)-dibenzo-oxazepines, -thiazepines, and -diazepines
ZA741610B (en) 1,2,4-triazole-3-carboxamides as antiviral agents
ZA74734B (en) Imidazo(1,2-a)azacycloalkanes
CA970373A (en) Pyrazolo (3,4-b) pyridine-5-carboxamides
ZA741268B (en) Imidazo (4,5-f) quinolin-9-ols
CA1022554A (en) 1-carbamoyl-2-alkoxycarbonylaminoimidazo (4,5-b) pyridines
CA1022188A (en) Antiviral 1,2,3,4-tetrahydro-1,4-alkanonaphthalenamine derivatives
CA1031335A (en) 6,7,8,9-tetrahydro-1h-pyrazolo (3,4-b) (1,5) diazocines
ZA747367B (en) 3,3a-dihydro-2h,9h-isoxazolo(3,2-b) (1,3) benzoxazin-9-ones
GB1482549A (en) 3-amino-isothiazolo(3,4-d)pyrimidines
IL48972A (en) 5-substituted-triazolo (3,4-b)(1,3,4)-cycloalkathiadiazine derivatives
NZ179990A (en) 2-aminomethylene-1,2-dihydor-4h-imidazo (1,2-a) (1,4)-benzodiazepin-1-ones
ZM12174A1 (en) 7h-indolizino (5,6,7-ij) isoquinoline derivatives
AU505275B2 (en) IMIDAZO (1, 2-b) ISOQUINOLINE DERIVATIVES
AU482017B2 (en) 1, 2, 4-triazole-3-carboxamides as antiviral agents
CA884895A (en) Thiazolo (3,2-a) pyrimidine derivatives
CA857328A (en) 1,2,3,4-tetrahydro-5h-(1)benzopyrano-(3,4-d) pyridines