CA1021280A - Cephalosporin conversion by rhodotorula - Google Patents

Cephalosporin conversion by rhodotorula

Info

Publication number
CA1021280A
CA1021280A CA199,614A CA199614A CA1021280A CA 1021280 A CA1021280 A CA 1021280A CA 199614 A CA199614 A CA 199614A CA 1021280 A CA1021280 A CA 1021280A
Authority
CA
Canada
Prior art keywords
rhodotorula
cephalosporin
conversion
cephalosporin conversion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA199,614A
Other languages
English (en)
Other versions
CA199614S (en
Inventor
Alan Smith
Stephen A. Goulden
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Laboratories Ltd
Original Assignee
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Laboratories Ltd filed Critical Glaxo Laboratories Ltd
Application granted granted Critical
Publication of CA1021280A publication Critical patent/CA1021280A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
CA199,614A 1973-05-14 1974-05-13 Cephalosporin conversion by rhodotorula Expired CA1021280A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2279973A GB1474519A (xx) 1973-05-14 1973-05-14

Publications (1)

Publication Number Publication Date
CA1021280A true CA1021280A (en) 1977-11-22

Family

ID=10185247

Family Applications (1)

Application Number Title Priority Date Filing Date
CA199,614A Expired CA1021280A (en) 1973-05-14 1974-05-13 Cephalosporin conversion by rhodotorula

Country Status (12)

Country Link
US (1) US3912589A (xx)
JP (1) JPS5443598B2 (xx)
AT (1) AT335057B (xx)
BE (1) BE814937A (xx)
CA (1) CA1021280A (xx)
CH (1) CH606002A5 (xx)
DE (1) DE2423058C2 (xx)
ES (1) ES426272A1 (xx)
FR (1) FR2229701B1 (xx)
GB (1) GB1474519A (xx)
NL (1) NL159716B (xx)
ZA (1) ZA743023B (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3976546A (en) * 1974-11-08 1976-08-24 Glaxo Laboratories Limited Cephalosporins
JPS5423372A (en) * 1977-07-22 1979-02-21 Hitachi Ltd Counter circuit
US4135978A (en) * 1977-08-19 1979-01-23 Merck & Co., Inc. Production of n-acyl-thienamycins
US4162193A (en) * 1977-08-19 1979-07-24 Merck & Co., Inc. Enzymatic cleavage of N-acyl-thienamycins
ZA804357B (en) * 1979-07-19 1981-08-26 Glaxo Group Ltd Production of a cephalosporin by fermentation
US4414328A (en) * 1980-07-21 1983-11-08 Fujisawa Pharmaceutical Co., Ltd. Process for the preparation of deacetylcephalosporin C
US4474879A (en) * 1982-11-16 1984-10-02 Eli Lilly And Company Process for 3-hydroxymethyl cephalosporin sulfones
DE3432060A1 (de) * 1984-08-31 1986-03-06 Bayer Ag, 5090 Leverkusen Immobilisierte zellen von bacillus subtilis, immobilisierungsverfahren und verwendung des praeparats zur abspaltung der 3-acetoxygruppe aus 7-ss-acylamido-cephalosporansaeuren
US4872899A (en) * 1985-04-02 1989-10-10 Utah State University Foundation Treatment of plant chlorosis with rhodotorulic acid
EP0409521B1 (en) * 1989-07-19 1995-10-11 Eli Lilly And Company Improved enzymatic oxidation of ceph C to glutaryl-7-amino-cephalosporanic acid
IT1247964B (it) * 1991-06-03 1995-01-05 Ministero Dell Uni E Della Processo per la preparazione enzimatica di derivati cefalosporanici
US5512454A (en) * 1994-02-03 1996-04-30 Bristol-Myers Squibb Company Enzymatic acylation of 3-hydroxymethyl cephalosporins
WO1995035020A2 (en) * 1994-07-22 1995-12-28 Antibioticos S.P.A. Glutaryl 7-aca derivatives and processes for obtaining them
US6080590A (en) * 1995-04-21 2000-06-27 Rijksuniversiteit Te Leiden On-line coupling biochemical detection to continuous flow separation techniques
AT411996B (de) * 2000-09-11 2004-08-26 Sandoz Ag Verfahren zur herstellung von cefuroxim in der form seines n-butylammoniumsalzes
CN102702231B (zh) * 2012-06-18 2014-10-29 山东大学 一种3-去氨甲酰基-头孢呋辛酸的制备方法
CN109553629B (zh) * 2018-12-26 2020-06-23 浙江永宁药业股份有限公司 一种头孢呋辛钠中间体e型杂质化合物的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1445639B2 (de) * 1963-11-19 1976-09-09 Ciba-Geigy Ag, Basel (Schweiz) Verfahren zur herstellung von desacetyl-7-aminocephalosporansaeure
CH475284A (de) * 1963-11-19 1969-07-15 Ciba Geigy Verfahren zur Herstellung von Desacetyl-7-amino-cephalosporansäure
GB1121308A (en) * 1964-10-30 1968-07-24 Glaxo Lab Ltd Cephalosporins
FR1460131A (fr) * 1964-10-30 1966-06-17 Glaxo Lab Ltd Procédé de préparation de produits de dégradation de la céphalosporine c et de ses dérivés

Also Published As

Publication number Publication date
AU6885574A (en) 1975-11-13
NL159716B (nl) 1979-03-15
BE814937A (fr) 1974-11-13
GB1474519A (xx) 1977-05-25
AT335057B (de) 1977-02-25
JPS5443598B2 (xx) 1979-12-20
ZA743023B (en) 1975-05-28
JPS5035395A (xx) 1975-04-04
US3912589A (en) 1975-10-14
FR2229701B1 (xx) 1978-02-17
DE2423058C2 (de) 1982-06-24
FR2229701A1 (xx) 1974-12-13
NL7406418A (xx) 1974-11-18
ES426272A1 (es) 1976-07-01
ATA392874A (de) 1976-06-15
DE2423058A1 (de) 1974-12-12
CH606002A5 (xx) 1978-10-13

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