CA1017750A - Anthelmintically active 2-carbalkoxy-amino-benzimidazole-5(6)-phenyl ethers and process for preparing them - Google Patents

Anthelmintically active 2-carbalkoxy-amino-benzimidazole-5(6)-phenyl ethers and process for preparing them

Info

Publication number
CA1017750A
CA1017750A CA159,777A CA159777A CA1017750A CA 1017750 A CA1017750 A CA 1017750A CA 159777 A CA159777 A CA 159777A CA 1017750 A CA1017750 A CA 1017750A
Authority
CA
Canada
Prior art keywords
carbalkoxy
benzimidazole
amino
preparing
phenyl ethers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA159,777A
Other languages
English (en)
Other versions
CA159777S (en
Inventor
Reinhard Kirsch
Dieter Duwel
Heinz Loewe
Josef Urbanietz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of CA1017750A publication Critical patent/CA1017750A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical
    • C07D235/32—Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Fodder In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA159,777A 1971-12-27 1972-12-22 Anthelmintically active 2-carbalkoxy-amino-benzimidazole-5(6)-phenyl ethers and process for preparing them Expired CA1017750A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2164690A DE2164690C3 (de) 1971-12-27 1971-12-27 Anthelmintisch wirksame 5-Phenoxy- und 5-Phenylthiobenzimidazolyl-(2)-carbamin-säuremethylester und Verfahren zu ihrer Herstellung

Publications (1)

Publication Number Publication Date
CA1017750A true CA1017750A (en) 1977-09-20

Family

ID=5829297

Family Applications (1)

Application Number Title Priority Date Filing Date
CA159,777A Expired CA1017750A (en) 1971-12-27 1972-12-22 Anthelmintically active 2-carbalkoxy-amino-benzimidazole-5(6)-phenyl ethers and process for preparing them

Country Status (30)

Country Link
US (1) US3954791A (ru)
JP (1) JPS5033067B2 (ru)
KR (1) KR780000116B1 (ru)
AT (1) AT320638B (ru)
AU (1) AU465226B2 (ru)
BE (1) BE793358A (ru)
BG (2) BG20591A3 (ru)
CA (1) CA1017750A (ru)
CH (2) CH580080A5 (ru)
CS (2) CS173615B2 (ru)
DD (2) DD109219A5 (ru)
DE (1) DE2164690C3 (ru)
DK (1) DK130293B (ru)
EG (1) EG11122A (ru)
ES (1) ES409860A1 (ru)
FI (1) FI54299C (ru)
FR (1) FR2166048B1 (ru)
GB (1) GB1360180A (ru)
HU (1) HU165060B (ru)
IL (1) IL41170A (ru)
IT (1) IT1043888B (ru)
KE (1) KE2613A (ru)
MY (1) MY7600092A (ru)
NL (1) NL153187B (ru)
NO (1) NO137092C (ru)
PL (1) PL85192B1 (ru)
RO (1) RO71503A (ru)
SE (1) SE395890B (ru)
SU (2) SU492086A3 (ru)
ZA (1) ZA729076B (ru)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3965113A (en) * 1972-12-29 1976-06-22 Syntex (U.S.A.) Inc. 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity
HU169503B (ru) * 1974-02-05 1976-12-28
RO64921A (fr) * 1974-05-28 1979-07-15 Syntex Inc Procede pour la preparation des derives des benzimidazole-2-carbamates
DE2432631A1 (de) * 1974-07-06 1976-01-22 Hoechst Ag 5-phenylsulfinyl-2-benzimidazol-carbaminsaeureester und verfahren zu ihrer herstellung
DE2441201C2 (de) * 1974-08-28 1986-08-07 Hoechst Ag, 6230 Frankfurt Anthelminthisch wirksame 2-Carbalkoxyamino-5(6)-phenyl-sulfonyloxy-benzimidazole und Verfahren zu ihrer Herstellung
DE2441202C2 (de) * 1974-08-28 1986-05-28 Hoechst Ag, 6230 Frankfurt 2-Carbalkoxyamino-benzimidazolyl-5(6)-sulfonsäure-phenylester, Verfahren zu ihrer Herstellung und diese enthaltende anthelmintische Mittel
US4076828A (en) * 1977-02-17 1978-02-28 E. R. Squibb & Sons, Inc. Method of treating helminthiasis by parenteral administration of sulfoxide derivatives of benzimidazoles
US4076827A (en) * 1977-04-28 1978-02-28 E. R. Squibb & Sons, Inc. Method of treating helminthiasis by parenteral administration of sulfoxide derivatives of benzimidazoles
US4076825A (en) * 1977-06-22 1978-02-28 E. R. Squibb & Sons, Inc. Method of treating helminthiasis by parenteral or topical administration of sulfoxide derivatives of benzimidazoles
IT1076022B (it) * 1977-04-20 1985-04-22 Montedison Spa Benzimidazolcarbammati antielmintici
SE443977B (sv) * 1977-05-10 1986-03-17 Chinoin Gyogyszer Es Vegyeszet Forfarande for framstellning av 5(6)-tio-bensimidazolderivat
US4136174A (en) * 1978-01-18 1979-01-23 E. R. Squibb & Sons, Inc. Benzimidazolecarbamates and method
US4156006A (en) * 1978-01-09 1979-05-22 E. R. Squibb & Sons, Inc. Vinyl sulfide derivatives of benzimidazoles
US4154846A (en) * 1978-06-16 1979-05-15 E. R. Squibb & Sons, Inc. Substituted thio-, sulfinyl-, and sulfonyl-alkyl benzimidazole carbamates
EP0028455A1 (en) * 1979-10-12 1981-05-13 Imperial Chemical Industries Plc 5-Phenylselenobenzimidazole derivatives, their preparation and anthelmintic or fasciolicidal compositions containing them
US4299837A (en) 1979-12-05 1981-11-10 Montedison S.P.A. Anthelmintic benzimidazole-carbamates
US4662935A (en) * 1980-01-14 1987-05-05 Rohm And Haas Company Herbicidal 4-trifluoromethyl-4-nitrodiphenyl ethers
DE3260986D1 (en) * 1981-03-18 1984-11-22 Ciba Geigy Ag Anthelmintics
IE56125B1 (en) * 1982-10-28 1991-04-24 Ici Plc Indole derivatives
NZ232785A (en) * 1989-03-15 1991-03-26 Janssen Pharmaceutica Nv 5-(1,2 benzisoxazol-, benzimidazol and benzisothiazol-3- yl)-1h-benzimadazol-2-yl carbamic acid ester derivatives preparatory processes, intermediates and anthelmintic compositions
WO1990010630A1 (en) * 1989-03-15 1990-09-20 Janssen Pharmaceutica N.V. [5(6)-(benzisoxa-, benzisothia- or indazol-3-yl)-1h-benzimidazol-2-yl] carbamates
US5538989A (en) * 1993-11-10 1996-07-23 Hoechst-Roussel Agri-Vet Company Fenbendazole formulations
US5861142A (en) * 1996-03-25 1999-01-19 Schick; Mary Pichler Method for promoting hair, nail, and skin keratinization
GB9900752D0 (en) 1999-01-15 1999-03-03 Angiogene Pharm Ltd Benzimidazole vascular damaging agents
US7396819B2 (en) 2003-08-08 2008-07-08 Virbac Corporation Anthelmintic formulations
US7582612B2 (en) * 2004-03-12 2009-09-01 Hartz Mountain Corporation Multi-action anthelmintic formulations
CA2616512A1 (en) * 2005-07-28 2007-02-08 Intervet International B.V. Novel benzimidazole (thio) carbamates with antiparasitic activity and the synthesis thereof
CN102283698B (zh) * 2006-06-12 2016-02-24 史密夫和内修有限公司 用于进行胫骨切除的引导装置
EP2037914B1 (en) 2006-06-14 2013-10-23 Intervet International BV A suspension comprising benzimidazole carbamate and a polysorbate
US11028055B2 (en) 2015-11-30 2021-06-08 Children's Medical Center Corporation Compounds for treating proliferative diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3480642A (en) * 1967-03-22 1969-11-25 Smithkline Corp Process for producing 2-carbalkoxyaminobenzimidazoles
DK131821C (da) * 1967-03-22 1976-03-08 Smith Kline French Lab Analogifremgangsmade til fremstilling af en 2-karbalkoksyaminobenzimidazol
FR2063815A5 (en) * 1969-10-31 1971-07-09 Aries Robert Antifungal and anthelmintic benzimidazole carbamates

Also Published As

Publication number Publication date
AU5048672A (en) 1974-06-27
JPS5033067B2 (ru) 1975-10-27
DK130293C (ru) 1975-06-30
AT320638B (de) 1975-02-25
MY7600092A (en) 1976-12-31
RO71503A (ro) 1981-01-30
CH580080A5 (ru) 1976-09-30
IL41170A (en) 1977-01-31
DD109219A5 (ru) 1974-10-20
DD110760A5 (ru) 1975-01-12
CH583710A5 (ru) 1977-01-14
FR2166048A1 (ru) 1973-08-10
US3954791A (en) 1976-05-04
FI54299B (fi) 1978-07-31
PL85192B1 (ru) 1976-04-30
NL153187B (nl) 1977-05-16
FR2166048B1 (ru) 1976-07-02
KE2613A (en) 1976-04-15
DK130293B (da) 1975-02-03
AU465226B2 (en) 1975-09-18
CS173615B2 (ru) 1977-02-28
NO137092B (no) 1977-09-19
CS173650B2 (ru) 1977-02-28
DE2164690C3 (de) 1981-04-16
SU492086A3 (ru) 1975-11-15
ES409860A1 (es) 1975-11-16
FI54299C (fi) 1978-11-10
IL41170A0 (en) 1973-02-28
EG11122A (en) 1977-05-31
SU493967A3 (ru) 1975-11-28
NL7217532A (ru) 1973-06-29
IT1043888B (it) 1980-02-29
BG22080A3 (ru) 1976-11-25
JPS4880558A (ru) 1973-10-29
SE395890B (sv) 1977-08-29
NO137092C (no) 1977-12-28
GB1360180A (en) 1974-07-17
KR780000116B1 (en) 1978-04-15
DE2164690B2 (de) 1980-08-14
ZA729076B (en) 1973-11-28
BE793358A (fr) 1973-06-27
HU165060B (ru) 1974-06-28
BG20591A3 (ru) 1975-12-05
DE2164690A1 (de) 1973-07-12

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