CA1014560A - M-dioxane-5-methylamine analgesics - Google Patents

M-dioxane-5-methylamine analgesics

Info

Publication number
CA1014560A
CA1014560A CA187,516A CA187516A CA1014560A CA 1014560 A CA1014560 A CA 1014560A CA 187516 A CA187516 A CA 187516A CA 1014560 A CA1014560 A CA 1014560A
Authority
CA
Canada
Prior art keywords
analgesics
methylamine
dioxane
methylamine analgesics
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA187,516A
Other languages
English (en)
Other versions
CA187516S (en
Inventor
Richard N. Booher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of CA1014560A publication Critical patent/CA1014560A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55Acids; Esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/041,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/061,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA187,516A 1972-12-08 1973-12-06 M-dioxane-5-methylamine analgesics Expired CA1014560A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31322172A 1972-12-08 1972-12-08

Publications (1)

Publication Number Publication Date
CA1014560A true CA1014560A (en) 1977-07-26

Family

ID=23214841

Family Applications (2)

Application Number Title Priority Date Filing Date
CA187,516A Expired CA1014560A (en) 1972-12-08 1973-12-06 M-dioxane-5-methylamine analgesics
CA187,636A Expired CA1024150A (en) 1972-12-08 1973-12-07 M-dioxane-5-methylamine analgesics

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA187,636A Expired CA1024150A (en) 1972-12-08 1973-12-07 M-dioxane-5-methylamine analgesics

Country Status (27)

Country Link
JP (2) JPS5742633B2 (pt)
AR (3) AR206306A1 (pt)
AT (2) AT330773B (pt)
BE (1) BE808340A (pt)
BG (4) BG22386A3 (pt)
CA (2) CA1014560A (pt)
CH (4) CH605903A5 (pt)
CS (3) CS222209B2 (pt)
CY (1) CY1017A (pt)
DD (3) DD110864A5 (pt)
DE (1) DE2361340C2 (pt)
DK (1) DK134717B (pt)
ES (4) ES421290A1 (pt)
FR (1) FR2209578B1 (pt)
GB (2) GB1455998A (pt)
HK (1) HK60479A (pt)
HU (2) HU168763B (pt)
IE (1) IE40226B1 (pt)
IL (1) IL43773A (pt)
KE (1) KE2976A (pt)
MY (1) MY8000064A (pt)
NL (1) NL7316839A (pt)
PH (2) PH15197A (pt)
SE (3) SE403377B (pt)
SU (4) SU578001A3 (pt)
YU (3) YU36171B (pt)
ZA (1) ZA739207B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2847177B1 (en) * 2012-05-09 2017-10-11 Boehringer Ingelheim International GmbH Methods for making oxetan-3-ylmethanamines
LV14983B (lv) * 2013-10-15 2015-06-20 Olainfarm, A/S Fenibuta ražošanas starpproduktu iegūšanas paņēmiens

Also Published As

Publication number Publication date
ES444911A1 (es) 1977-09-01
YU35447B (en) 1981-02-28
ZA739207B (en) 1975-07-30
NL7316839A (pt) 1974-06-11
DD109625A5 (pt) 1974-11-12
SE7701795L (sv) 1977-02-17
ES421291A1 (es) 1976-07-01
ES421290A1 (es) 1976-07-01
YU318473A (en) 1980-09-25
SE403377B (sv) 1978-08-14
IL43773A (en) 1979-05-31
HU168763B (pt) 1976-07-28
SE7701796L (sv) 1977-02-17
HU168620B (pt) 1976-06-28
CS222209B2 (en) 1983-05-27
IE40226L (en) 1974-06-08
AU6321773A (en) 1975-06-05
FR2209578B1 (pt) 1977-09-02
DE2361340C2 (de) 1983-11-24
JPS5734835B2 (pt) 1982-07-26
ES444716A1 (es) 1977-05-16
DK134717C (pt) 1977-05-31
DD115653A5 (pt) 1975-10-12
GB1455998A (en) 1976-11-17
CS222208B2 (en) 1983-05-27
CH619219A5 (en) 1980-09-15
AR212416A1 (es) 1978-07-14
YU318573A (en) 1981-06-30
DD110864A5 (pt) 1975-01-12
ATA1026173A (de) 1976-01-15
SU587861A3 (ru) 1978-01-05
CH605903A5 (pt) 1978-10-13
PH15197A (en) 1982-09-17
SU648081A3 (ru) 1979-02-15
BG26205A4 (bg) 1979-02-15
CY1017A (en) 1979-11-23
AR206306A1 (es) 1976-07-15
SU663305A3 (ru) 1979-05-15
HK60479A (en) 1979-08-31
ATA1026073A (de) 1975-10-15
BG21409A3 (bg) 1976-05-20
JPS4987680A (pt) 1974-08-22
IL43773A0 (en) 1974-03-14
CA1024150A (en) 1978-01-10
CH614439A5 (en) 1979-11-30
CS193480B2 (en) 1979-10-31
DK134717B (da) 1977-01-03
MY8000064A (en) 1980-12-31
YU36171B (en) 1982-02-25
BE808340A (fr) 1974-06-07
JPS4987681A (pt) 1974-08-22
DE2361340A1 (de) 1974-06-12
YU36020B (en) 1981-11-13
GB1455997A (en) 1976-11-17
SE428378B (sv) 1983-06-27
AT330773B (de) 1976-07-26
IE40226B1 (en) 1979-04-11
YU109380A (en) 1981-04-30
BG21223A3 (bg) 1976-03-20
SE417196B (sv) 1981-03-02
AT332396B (de) 1976-09-27
KE2976A (en) 1979-07-20
SU578001A3 (ru) 1977-10-25
BG22386A3 (bg) 1977-02-20
PH14923A (en) 1982-01-29
JPS5742633B2 (pt) 1982-09-09
FR2209578A1 (pt) 1974-07-05
AR212012A1 (es) 1978-04-28
CH630914A5 (en) 1982-07-15

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