CA1013748A - Procede de preparation de derives des/4'-(3"-indolyl) piperidino/alcoyl-arylcetones - Google Patents

Procede de preparation de derives des/4'-(3"-indolyl) piperidino/alcoyl-arylcetones

Info

Publication number
CA1013748A
CA1013748A CA177,501A CA177501A CA1013748A CA 1013748 A CA1013748 A CA 1013748A CA 177501 A CA177501 A CA 177501A CA 1013748 A CA1013748 A CA 1013748A
Authority
CA
Canada
Prior art keywords
arylcetone
alcoyl
piperidino
indolyl
preparation process
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA177,501A
Other languages
English (en)
Other versions
CA177501S (en
Inventor
Pierre H. Derible
Jean-Paul Lavaux
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Application granted granted Critical
Publication of CA1013748A publication Critical patent/CA1013748A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
CA177,501A 1972-07-28 1973-07-27 Procede de preparation de derives des/4'-(3"-indolyl) piperidino/alcoyl-arylcetones Expired CA1013748A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7227263A FR2193584B1 (fr) 1972-07-28 1972-07-28

Publications (1)

Publication Number Publication Date
CA1013748A true CA1013748A (fr) 1977-07-12

Family

ID=9102514

Family Applications (1)

Application Number Title Priority Date Filing Date
CA177,501A Expired CA1013748A (fr) 1972-07-28 1973-07-27 Procede de preparation de derives des/4'-(3"-indolyl) piperidino/alcoyl-arylcetones

Country Status (15)

Country Link
US (1) US3850938A (fr)
JP (1) JPS562555B2 (fr)
AU (1) AU472530B2 (fr)
BE (1) BE802912A (fr)
CA (1) CA1013748A (fr)
CH (1) CH571500A5 (fr)
DE (1) DE2365967C3 (fr)
DK (1) DK134991B (fr)
ES (1) ES417333A1 (fr)
FR (1) FR2193584B1 (fr)
GB (1) GB1382782A (fr)
IL (1) IL42781A (fr)
NL (1) NL7310268A (fr)
SE (1) SE406589B (fr)
ZA (1) ZA734998B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2322470A1 (de) * 1973-05-04 1974-11-21 Boehringer Sohn Ingelheim Neue indolyl-piperidino-(bzw. 1,2,5,6tetrahydro-pyridyl-)butyrophenone und verfahren zu ihrer herstellung
IL48508A (en) * 1974-12-09 1979-10-31 Roussel Uclaf Pharmaceutical compositions comprising piperidylindole derivatives
US4046900A (en) * 1975-08-08 1977-09-06 American Hoechst Corporation Benzoylpiperidylalkylindoles
DE2708913A1 (de) * 1976-03-04 1977-09-08 Hoechst Ag Benzoylpiperidyalkyl-indole und verwandte verbindungen
FR2349331A1 (fr) * 1976-04-30 1977-11-25 Roussel Uclaf Nouveaux derives de 2,3 dihydro a/4-(3-indolyl) 1-piperidinyl/methyl 1,4-benzodioxin-2-methanol, un procede pour leur preparation et leur application comme medicaments
FR2362628A1 (fr) * 1976-08-26 1978-03-24 Roussel Uclaf Nouveaux derives du piperidyl-indole et leurs sels, procede de preparation et application a titre de medicaments
FR2420536A1 (fr) * 1978-03-22 1979-10-19 Roussel Uclaf Nouveaux derives de 1,3-dihydro 3-/1-/2-(2,3-dihydro 1,4-benzodioxin-2-yl)2-hydroxyethyl/piperidin-4-yl/2h-indol-2-one, procede pour leur preparation et application comme medicaments
US4166120A (en) * 1978-04-14 1979-08-28 American Hoechst Corporation Analgesic and tranquilizing benzoylpropyl-spiro[dihydrobenzofuran]piperidines and pyrrolidines
FR2444678A2 (fr) * 1978-12-22 1980-07-18 Roussel Uclaf Nouveau procede de preparation de derives du piperidyl-indole et de leurs sels
FR2460947A1 (fr) * 1979-07-13 1981-01-30 Roussel Uclaf Nouveau derives n-substitues du tetrahydropyridinyl-indole, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
IE58370B1 (en) * 1985-04-10 1993-09-08 Lundbeck & Co As H Indole derivatives
US4742057A (en) * 1985-12-05 1988-05-03 Fujisawa Pharmaceutical Co., Ltd. Antiallergic thiazole compounds
DK733788A (da) * 1988-01-14 1989-07-15 Fujisawa Pharmaceutical Co Indolylpiperidinderivater og fremgangsmaade til fremstilling deraf
US5521196A (en) * 1994-10-05 1996-05-28 Eli Lilly And Company 5-HT1F agonists for the treatment of migraine
US5521197A (en) * 1994-12-01 1996-05-28 Eli Lilly And Company 3-<1-alkylenearyl>-4-<1,2,3,6-tetrahydropyridinyl>-and 3-<1-alkylenearyl>-4-piperidinyl-1h-indoles: new 5-HT1F agonists
TR199700993T1 (xx) * 1995-03-20 1998-03-21 Eli Lilly And Company 5-ikameli-3-(1,2,3,6-tetrahidropridin-4-il)- ve 3-(piperidin-4-il)-1H-indoller: yeni 5-HT1F agonistler.
AR013669A1 (es) * 1997-10-07 2001-01-10 Smithkline Beecham Corp Compuestos y metodos
JP2008076126A (ja) * 2006-09-20 2008-04-03 Oputo System:Kk 測光装置及び測光方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB925429A (en) * 1960-04-01 1963-05-08 Irwin Neisler & Co Indole derivatives
US3462440A (en) * 1965-12-03 1969-08-19 American Home Prod 1,4-bis(2-indol-3-ylethyl)piperidines

Also Published As

Publication number Publication date
DE2338283A1 (de) 1974-02-07
GB1382782A (en) 1975-02-05
ZA734998B (en) 1974-09-25
US3850938A (en) 1974-11-26
DK134991C (fr) 1977-09-26
DK134991B (da) 1977-02-21
DE2365967A1 (de) 1977-02-10
DE2365967C3 (de) 1978-08-31
NL7310268A (fr) 1974-01-30
JPS562555B2 (fr) 1981-01-20
IL42781A (en) 1976-07-30
JPS4962481A (fr) 1974-06-17
ES417333A1 (es) 1976-02-16
AU5862973A (en) 1975-01-30
CH571500A5 (fr) 1976-01-15
FR2193584B1 (fr) 1975-08-08
BE802912A (fr) 1974-01-28
DE2338283B2 (de) 1977-06-02
SE406589B (sv) 1979-02-19
AU472530B2 (en) 1976-05-27
FR2193584A1 (fr) 1974-02-22
IL42781A0 (en) 1973-10-25
DE2365967B2 (de) 1977-12-22

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