CA1011731A - 3-methylene cephalosporins - Google Patents

3-methylene cephalosporins

Info

Publication number
CA1011731A
CA1011731A CA135,453A CA135453A CA1011731A CA 1011731 A CA1011731 A CA 1011731A CA 135453 A CA135453 A CA 135453A CA 1011731 A CA1011731 A CA 1011731A
Authority
CA
Canada
Prior art keywords
cephalosporins
methylene
methylene cephalosporins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA135,453A
Other languages
English (en)
Other versions
CA135453S (en
Inventor
Robert R. Chauvette
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Priority to CA214,467A priority Critical patent/CA1012133A/en
Application granted granted Critical
Publication of CA1011731A publication Critical patent/CA1011731A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/227-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
CA135,453A 1971-02-25 1972-02-24 3-methylene cephalosporins Expired CA1011731A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA214,467A CA1012133A (en) 1971-02-25 1974-11-22 .delta.3 cephem compounds and process of preparing same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/118,941 US3932393A (en) 1971-02-25 1971-02-25 3-Methylenecephalosporins and process for production thereof

Publications (1)

Publication Number Publication Date
CA1011731A true CA1011731A (en) 1977-06-07

Family

ID=22381674

Family Applications (1)

Application Number Title Priority Date Filing Date
CA135,453A Expired CA1011731A (en) 1971-02-25 1972-02-24 3-methylene cephalosporins

Country Status (30)

Country Link
US (1) US3932393A (sv)
JP (2) JPS5516154B1 (sv)
AR (3) AR193637A1 (sv)
AT (2) AT318809B (sv)
BE (1) BE779305A (sv)
BG (2) BG22839A3 (sv)
CA (1) CA1011731A (sv)
CH (2) CH574964A5 (sv)
CS (2) CS183696B2 (sv)
DD (1) DD96072A5 (sv)
DE (1) DE2209020C2 (sv)
ES (3) ES400089A1 (sv)
FI (1) FI57419C (sv)
FR (1) FR2127798A5 (sv)
GB (1) GB1358963A (sv)
HU (1) HU163864B (sv)
IE (1) IE36084B1 (sv)
IL (1) IL38764A (sv)
LU (1) LU64811A1 (sv)
MX (1) MX4162E (sv)
NL (1) NL173646C (sv)
NO (3) NO147916C (sv)
OA (1) OA03967A (sv)
PH (2) PH9807A (sv)
PL (2) PL88957B1 (sv)
RO (3) RO62694A (sv)
SE (2) SE417207B (sv)
SU (2) SU442602A3 (sv)
YU (1) YU36524B (sv)
ZA (1) ZA72796B (sv)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE412238B (sv) * 1971-05-24 1980-02-25 Ciba Geigy Forfarande for framstellning av 7 beta-amino-cefem-4-karboxylsyraforeningar genom dekarbonylering av en 3-formyl-cefem-4-karboxylsyraforening
US4008228A (en) * 1971-12-06 1977-02-15 Eli Lilly And Company Process for preparing 3-methyl-3-cephem antibiotics
US4060688A (en) * 1972-11-28 1977-11-29 Eli Lilly And Company Cephalosporin intermediates
CA1022542A (en) * 1973-01-09 1977-12-13 Bruno Fechtig Process for the manufacture of methylene compounds
US4031082A (en) * 1976-01-19 1977-06-21 Eli Lilly And Company Process for preparing 3-acycloxymethyl-2-cephem compounds
US4042472A (en) * 1976-04-12 1977-08-16 Eli Lilly And Company Electrolytic process for 7-methoxy-3-exomethylenecepham compounds
US4129731A (en) * 1976-12-08 1978-12-12 E. R. Squibb & Sons, Inc. Process for converting 3-methylene cephalosporins to 3-heterothiomethyl cephalosporins
US4176231A (en) * 1977-12-24 1979-11-27 Lilly Industries Limited Process for preparing 3-exomethylenecepham sulfoxides
US4211702A (en) * 1979-02-01 1980-07-08 Eli Lilly And Company Process for preparation of penicillin and cephalosporin imino halides
US4354022A (en) * 1981-06-05 1982-10-12 Fujisawa Pharmaceutical Co., Ltd. Process for preparing 3-methylenecepham compounds or a salt thereof
US5604222A (en) * 1993-12-27 1997-02-18 Lupin Laboratories, Ltd. Method for the preparation of 2-chloro sulfinyl azetidinones
US5578721A (en) * 1994-07-11 1996-11-26 Lupin Laboratories Limited Process for preparation of 3-exomethylene cepham sulfoxide esters
US5571910A (en) * 1994-12-09 1996-11-05 Schering Corporation Process for the preparation of intermediates useful in the synthesis of cephalosporins
KR100390549B1 (ko) * 1996-07-22 2003-11-17 주식회사 코오롱 3-할로메틸-3-세펨의 제조방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1279402A (en) * 1968-06-14 1972-06-28 Glaxo Lab Ltd Improvements in or relating to cephalosporin derivatives
US3660396A (en) * 1970-03-04 1972-05-02 Lilly Co Eli Cephalosporin intermediates and process therefor
US3660395A (en) * 1970-03-04 1972-05-02 Lilly Co Eli Thioether cephalosporin compounds

Also Published As

Publication number Publication date
NO147916C (no) 1983-07-06
CS183696B2 (en) 1978-07-31
ES427863A1 (es) 1976-09-01
BG22839A3 (bg) 1977-04-20
NO147916B (no) 1983-03-28
ES427861A1 (es) 1976-08-01
NL173646C (nl) 1984-02-16
JPS5598187A (en) 1980-07-25
PH9807A (en) 1976-03-26
BE779305A (fr) 1972-08-11
SE417969B (sv) 1981-04-27
IL38764A0 (en) 1972-04-27
JPS564557B2 (sv) 1981-01-30
FI57419C (fi) 1980-08-11
YU36524B (en) 1984-02-29
FI57419B (fi) 1980-04-30
IE36084B1 (en) 1976-08-18
BG20116A3 (bg) 1975-10-30
LU64811A1 (sv) 1973-01-05
CH567514A5 (sv) 1975-10-15
SE417207B (sv) 1981-03-02
AR193670A1 (es) 1973-05-11
CH574964A5 (sv) 1976-04-30
DE2209020A1 (de) 1972-09-07
NO147917C (no) 1983-07-06
IE36084L (en) 1972-08-25
RO62695A (fr) 1978-03-15
RO62694A (fr) 1978-05-15
MX4162E (es) 1982-01-14
AU3888972A (en) 1973-08-16
SE7500871L (sv) 1975-01-28
DD96072A5 (sv) 1973-03-05
AT318809B (de) 1974-11-25
JPS5516154B1 (sv) 1980-04-30
NO147917B (no) 1983-03-28
FR2127798A5 (sv) 1972-10-13
DE2209020C2 (de) 1982-06-03
OA03967A (fr) 1979-08-31
NO147918B (no) 1983-03-28
AR201273A1 (es) 1975-02-28
YU45072A (en) 1982-02-25
PL88957B1 (sv) 1976-10-30
PL92431B1 (sv) 1977-04-30
IL38764A (en) 1975-02-10
GB1358963A (en) 1974-07-03
US3932393A (en) 1976-01-13
AT318804B (de) 1974-11-25
HU163864B (sv) 1973-11-28
PH10522A (en) 1977-05-26
SU628821A3 (ru) 1978-10-15
NO147918C (no) 1983-07-06
ES400089A1 (es) 1975-06-16
RO59021A (sv) 1975-12-15
ZA72796B (en) 1973-09-26
NL7202531A (sv) 1972-08-29
AR193637A1 (es) 1973-05-11
SU442602A3 (ru) 1974-09-05
CS183654B2 (en) 1978-07-31

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