CA1003441A - Process for the preparation of n-(trans-4-hydroxycyclohexyl)-(2-amino-3,5-dibromobenzyl)-amine - Google Patents

Process for the preparation of n-(trans-4-hydroxycyclohexyl)-(2-amino-3,5-dibromobenzyl)-amine

Info

Publication number
CA1003441A
CA1003441A CA168,938A CA168938A CA1003441A CA 1003441 A CA1003441 A CA 1003441A CA 168938 A CA168938 A CA 168938A CA 1003441 A CA1003441 A CA 1003441A
Authority
CA
Canada
Prior art keywords
dibromobenzyl
hydroxycyclohexyl
trans
amine
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA168,938A
Other languages
English (en)
Other versions
CA168938S (en
Inventor
Johannes Keck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Application granted granted Critical
Publication of CA1003441A publication Critical patent/CA1003441A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA168,938A 1972-04-18 1973-04-17 Process for the preparation of n-(trans-4-hydroxycyclohexyl)-(2-amino-3,5-dibromobenzyl)-amine Expired CA1003441A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19722218647 DE2218647A1 (de) 1972-04-18 1972-04-18 Neues verfahren zur herstellung von n-(trans-4-hydroxy-cyclohexyl)-(2-amino3,5-dibrom-benzyl)-amin

Publications (1)

Publication Number Publication Date
CA1003441A true CA1003441A (en) 1977-01-11

Family

ID=5842287

Family Applications (1)

Application Number Title Priority Date Filing Date
CA168,938A Expired CA1003441A (en) 1972-04-18 1973-04-17 Process for the preparation of n-(trans-4-hydroxycyclohexyl)-(2-amino-3,5-dibromobenzyl)-amine

Country Status (18)

Country Link
JP (1) JPS554096B2 (de)
AT (1) AT321270B (de)
BG (1) BG22807A3 (de)
CA (1) CA1003441A (de)
CH (1) CH575907A5 (de)
CS (1) CS174876B2 (de)
DD (1) DD107261A5 (de)
DE (1) DE2218647A1 (de)
DK (2) DK139515C (de)
ES (2) ES413827A1 (de)
FI (1) FI56522C (de)
HU (1) HU165758B (de)
NO (1) NO137086C (de)
PL (1) PL86344B1 (de)
RO (1) RO65104A (de)
SE (2) SE415970B (de)
SU (1) SU458976A3 (de)
YU (1) YU35573B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2223193C3 (de) * 1972-05-12 1975-05-28 Dr. Karl Thomae Gmbh, 7950 Biberach Verfahren zur Herstellung von 2-Amino-benzylaminen
US4020104A (en) * 1976-09-20 1977-04-26 The Upjohn Company Process for isomerizing cis,cis- and cis,trans-isomers of di-(p-aminocyclohexyl)methane to the corresponding trans,trans-isomer
DE2720867C2 (de) * 1977-05-10 1979-05-31 Kernforschungsanlage Juelich Gmbh, 5170 Juelich Verfahren zur quantitativen Abtrennung von Uran aus Proben natürlichen Wassers
ATE22069T1 (de) * 1983-06-29 1986-09-15 Heumann Ludwig & Co Gmbh Verfahren zur herstellung von 2-amino-3,5dibrombenzylaminen.
IT1216837B (it) * 1987-01-07 1990-03-14 Erregierre Ind Chim Sali della n-(trans-p-idrossi-cicloesil)-(2ammino-3,5-dibromo) benzilammina dotati di attivita' mucolitica.
HU207834B (en) * 1989-12-22 1993-06-28 Egyt Gyogyszervegyeszeti Gyar Process for producing n-/2-amino-3,5-dibromo-benzyl/-trans-4-amino-cyclohexanol

Also Published As

Publication number Publication date
ES421120A1 (es) 1976-06-16
FI56522C (fi) 1980-02-11
DD107261A5 (de) 1974-07-20
NO137086C (no) 1977-12-28
DK139515B (da) 1979-03-05
JPS4914443A (de) 1974-02-07
HU165758B (de) 1974-10-28
BG22807A3 (de) 1977-04-20
JPS554096B2 (de) 1980-01-29
DK139515C (da) 1979-08-20
SE7513808L (sv) 1975-12-08
RO65104A (fr) 1979-08-15
DE2218647A1 (de) 1973-10-25
PL86344B1 (de) 1976-05-31
SE415970B (sv) 1980-11-17
AT321270B (de) 1975-03-25
ES413827A1 (es) 1976-01-16
FI56522B (fi) 1979-10-31
NO137086B (no) 1977-09-19
SE421613B (sv) 1982-01-18
YU101773A (en) 1980-10-31
YU35573B (en) 1981-04-30
CH575907A5 (de) 1976-05-31
DK570776A (da) 1976-12-17
CS174876B2 (de) 1977-04-29
SU458976A3 (ru) 1975-01-30

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