BRPI1015023A2 - iniciadores e processos para polimerização aniônica. - Google Patents
iniciadores e processos para polimerização aniônica.Info
- Publication number
- BRPI1015023A2 BRPI1015023A2 BRPI1015023A BRPI1015023A BRPI1015023A2 BR PI1015023 A2 BRPI1015023 A2 BR PI1015023A2 BR PI1015023 A BRPI1015023 A BR PI1015023A BR PI1015023 A BRPI1015023 A BR PI1015023A BR PI1015023 A2 BRPI1015023 A2 BR PI1015023A2
- Authority
- BR
- Brazil
- Prior art keywords
- group
- initiators
- processes
- anionic polymerization
- polymerization
- Prior art date
Links
- 238000010539 anionic addition polymerization reaction Methods 0.000 title abstract 2
- 239000003999 initiator Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000006116 polymerization reaction Methods 0.000 abstract 2
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 239000000178 monomer Substances 0.000 abstract 1
- 239000003505 polymerization initiator Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F4/00—Polymerisation catalysts
- C08F4/42—Metals; Metal hydrides; Metallo-organic compounds; Use thereof as catalyst precursors
- C08F4/44—Metals; Metal hydrides; Metallo-organic compounds; Use thereof as catalyst precursors selected from light metals, zinc, cadmium, mercury, copper, silver, gold, boron, gallium, indium, thallium, rare earths or actinides
- C08F4/46—Metals; Metal hydrides; Metallo-organic compounds; Use thereof as catalyst precursors selected from light metals, zinc, cadmium, mercury, copper, silver, gold, boron, gallium, indium, thallium, rare earths or actinides selected from alkali metals
- C08F4/48—Metals; Metal hydrides; Metallo-organic compounds; Use thereof as catalyst precursors selected from light metals, zinc, cadmium, mercury, copper, silver, gold, boron, gallium, indium, thallium, rare earths or actinides selected from alkali metals selected from lithium, rubidium, caesium or francium
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
- C07F1/02—Lithium compounds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F36/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds
- C08F36/02—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds the radical having only two carbon-to-carbon double bonds
- C08F36/04—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds the radical having only two carbon-to-carbon double bonds conjugated
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F4/00—Polymerisation catalysts
- C08F4/42—Metals; Metal hydrides; Metallo-organic compounds; Use thereof as catalyst precursors
- C08F4/44—Metals; Metal hydrides; Metallo-organic compounds; Use thereof as catalyst precursors selected from light metals, zinc, cadmium, mercury, copper, silver, gold, boron, gallium, indium, thallium, rare earths or actinides
- C08F4/46—Metals; Metal hydrides; Metallo-organic compounds; Use thereof as catalyst precursors selected from light metals, zinc, cadmium, mercury, copper, silver, gold, boron, gallium, indium, thallium, rare earths or actinides selected from alkali metals
- C08F4/48—Metals; Metal hydrides; Metallo-organic compounds; Use thereof as catalyst precursors selected from light metals, zinc, cadmium, mercury, copper, silver, gold, boron, gallium, indium, thallium, rare earths or actinides selected from alkali metals selected from lithium, rubidium, caesium or francium
- C08F4/484—Metals; Metal hydrides; Metallo-organic compounds; Use thereof as catalyst precursors selected from light metals, zinc, cadmium, mercury, copper, silver, gold, boron, gallium, indium, thallium, rare earths or actinides selected from alkali metals selected from lithium, rubidium, caesium or francium an alkali metal bound to a cyclic carbon
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F12/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an aromatic carbocyclic ring
- C08F12/02—Monomers containing only one unsaturated aliphatic radical
- C08F12/04—Monomers containing only one unsaturated aliphatic radical containing one ring
- C08F12/06—Hydrocarbons
- C08F12/08—Styrene
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F136/00—Homopolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds
- C08F136/02—Homopolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds the radical having only two carbon-to-carbon double bonds
- C08F136/04—Homopolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds the radical having only two carbon-to-carbon double bonds conjugated
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F236/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds
- C08F236/02—Copolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds the radical having only two carbon-to-carbon double bonds
- C08F236/04—Copolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds the radical having only two carbon-to-carbon double bonds conjugated
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F2810/00—Chemical modification of a polymer
- C08F2810/40—Chemical modification of a polymer taking place solely at one end or both ends of the polymer backbone, i.e. not in the side or lateral chains
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Polymerization Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22162209P | 2009-06-30 | 2009-06-30 | |
| PCT/US2010/040242 WO2011008501A2 (en) | 2009-06-30 | 2010-06-28 | Anionic polymerization initiators and processes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI1015023A2 true BRPI1015023A2 (pt) | 2019-07-09 |
Family
ID=43450073
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1015023A BRPI1015023A2 (pt) | 2009-06-30 | 2010-06-28 | iniciadores e processos para polimerização aniônica. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9365660B2 (https=) |
| EP (1) | EP2448900B1 (https=) |
| JP (1) | JP5792162B2 (https=) |
| KR (1) | KR101752934B1 (https=) |
| CN (1) | CN102482186B (https=) |
| BR (1) | BRPI1015023A2 (https=) |
| ES (1) | ES2633097T3 (https=) |
| WO (1) | WO2011008501A2 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101657603B1 (ko) | 2007-12-28 | 2016-09-19 | 가부시키가이샤 브리지스톤 | 히드록시아릴 관능화 중합체 |
| CN102625814B (zh) | 2009-06-30 | 2014-08-06 | 株式会社普利司通 | 用包含羟基的二苯基乙烯官能化的聚合物 |
| JP5889787B2 (ja) * | 2009-07-01 | 2016-03-22 | 株式会社ブリヂストン | フリーラジカル開始重合によるヒドロキシアリール官能化共重合体の製造方法 |
| WO2011153109A2 (en) | 2010-05-31 | 2011-12-08 | Bridgestone Corporation | Hydroxyl group-containing methylstyrene and polymers incorporating same |
| US8637600B2 (en) | 2010-08-11 | 2014-01-28 | Bridgestone Corporation | Processing of rubber compositions including siliceous fillers |
| EP2888562A1 (en) * | 2012-08-21 | 2015-07-01 | Micro Motion, Inc. | Coriolis flowmeter and method with improved meter zero |
| DE102012017797B4 (de) * | 2012-09-10 | 2014-09-18 | Krohne Ag | Durchflussmessgerät |
| KR20160033105A (ko) | 2013-07-22 | 2016-03-25 | 트린세오 유럽 게엠베하 | 중합 개시제 |
| JP6795579B2 (ja) | 2015-07-22 | 2020-12-02 | 株式会社ブリヂストン | シラン官能化ポリマー並びにそれらを作製及び使用するためのプロセス |
| JP6809755B2 (ja) | 2015-11-13 | 2021-01-06 | 株式会社ブリヂストン | アニオン重合のための官能性開始剤 |
| US10815328B2 (en) | 2015-11-16 | 2020-10-27 | Bridgestone Corporation | Functional initiator for anionic polymerization |
| WO2017188641A2 (ko) * | 2016-04-25 | 2017-11-02 | 주식회사 엘지화학 | 변성 공액디엔계 중합체 및 이의 제조방법 |
| KR102014521B1 (ko) * | 2016-04-25 | 2019-10-21 | 주식회사 엘지화학 | 변성 공액디엔계 중합체 및 이의 제조방법 |
| KR102217592B1 (ko) | 2016-12-28 | 2021-02-22 | 화이어스톤 폴리머스, 엘엘씨 | 점착성이 감소된 중합체를 제조하는 방법, 및 이러한 중합체를 포함하는 고무 조성물 |
| KR102102986B1 (ko) | 2017-09-29 | 2020-04-21 | 주식회사 엘지화학 | 양 말단 변성 공액디엔계 중합체 및 이의 제조방법 |
| WO2019066279A1 (ko) * | 2017-09-29 | 2019-04-04 | 주식회사 엘지화학 | 양 말단 변성 공액디엔계 중합체 및 이의 제조방법 |
| CN109627382B (zh) * | 2017-10-06 | 2022-03-18 | 台橡股份有限公司 | 共轭二烯聚合物及其组合物及制造方法 |
| KR102241925B1 (ko) * | 2018-11-26 | 2021-04-20 | 주식회사 엘지화학 | 블록 공중합체 조성물, 이의 제조방법 및 이를 포함하는 아스팔트 조성물 |
Family Cites Families (67)
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|---|---|---|---|---|
| US3109871A (en) | 1960-12-27 | 1963-11-05 | Phillips Petroleum Co | Production and curing of polyfunctional terminally reactive polymers |
| US3668263A (en) | 1970-01-19 | 1972-06-06 | Lithium Corp | Organolithium polymerization initiators and use thereof in polymerization processes |
| US3978103A (en) | 1971-08-17 | 1976-08-31 | Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler | Sulfur containing organosilicon compounds |
| US3873489A (en) | 1971-08-17 | 1975-03-25 | Degussa | Rubber compositions containing silica and an organosilane |
| US4006187A (en) * | 1971-10-06 | 1977-02-01 | Lithium Corporation Of America | Preparation of aryllithium compounds by metalation |
| BE790802A (fr) * | 1971-11-04 | 1973-04-30 | Takeda Chemical Industries Ltd | Nouveaux derives de chromone et leur fabrication |
| JPS4941116A (https=) | 1972-09-06 | 1974-04-17 | ||
| US3931107A (en) * | 1973-06-21 | 1976-01-06 | Phillips Petroleum Company | Polyalkoxy monovinylaromatic compound in copolymerization of a conjugated diene with a monovinyl-substituted aromatic compound |
| SU580840A3 (ru) | 1974-02-07 | 1977-11-15 | Дегусса (Фирма) | Способ получени серосодержащих кремнийорганических соединений |
| US4015061A (en) | 1975-02-14 | 1977-03-29 | The Firestone Tire & Rubber Company | Protected amino-functional initiators and amino-terminated polymers and their production |
| US4002594A (en) | 1975-07-08 | 1977-01-11 | Ppg Industries, Inc. | Scorch retardants for rubber reinforced with siliceous pigment and mercapto-type coupling agent |
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| US4499243A (en) | 1983-11-07 | 1985-02-12 | Monsanto Company | Method of treating diene rubber with amino- and hydroxy aryl compounds |
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| US4935471A (en) | 1987-10-15 | 1990-06-19 | The Goodyear Tire & Rubber Company | Capped polydienes |
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| DE4003079A1 (de) | 1990-02-02 | 1991-08-08 | Bayer Ag | Benzophenonderivate und polymere mit phenolischen hydroxylgruppen |
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| CA2040457A1 (en) | 1990-04-30 | 1991-10-31 | Timothy E. Long | Block copolymers containing poly(1,3-conjugated dienes) and poly (vinylphenols), silyl protected poly (vinylphenols) or poly (metal phenolates) |
| JP3057508B2 (ja) * | 1990-06-21 | 2000-06-26 | 日本曹達株式会社 | p―アルケニルフェノール系重合体の製造方法 |
| JP2544016B2 (ja) * | 1990-10-11 | 1996-10-16 | 信越化学工業株式会社 | リチウム電池 |
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| JPH05230126A (ja) | 1992-02-25 | 1993-09-07 | Nippon Steel Chem Co Ltd | 芳香族ヒドロキシル基を有するスチレン系ポリマーとその製造法 |
| US5329005A (en) | 1992-10-02 | 1994-07-12 | Bridgestone Corporation | Soluble anionic polymerization initiators and preparation thereof |
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| JP3246172B2 (ja) | 1994-03-18 | 2002-01-15 | 住友化学工業株式会社 | ゴム組成物およびそれを用いるスチールコードとの加硫接着方法 |
| US5567815A (en) | 1994-07-18 | 1996-10-22 | Bridgestone Corporation | Teritary amine containing antonic initiators used in preparing polymers and process for the preparation thereof |
| US5521309A (en) | 1994-12-23 | 1996-05-28 | Bridgestone Corporation | Tertiary-amino allyl-or xylyl-lithium initiators and method of preparing same |
| US5496940A (en) | 1995-02-01 | 1996-03-05 | Bridgestone Corporation | Alkyllithium compounds containing cyclic amines and their use in polymerization |
| US5580919A (en) | 1995-03-14 | 1996-12-03 | The Goodyear Tire & Rubber Company | Silica reinforced rubber composition and use in tires |
| EP0745655A3 (en) | 1995-06-02 | 1998-04-29 | National Starch and Chemical Investment Holding Corporation | Dissipative laminating adhesive |
| US5610227A (en) | 1995-06-07 | 1997-03-11 | Bridgestone/Firestone, Inc. | Lithium amino magnesiate polymerization initiators and elastomers having reduced hysteresis |
| US5583245A (en) | 1996-03-06 | 1996-12-10 | The Goodyear Tire & Rubber Company | Preparation of sulfur-containing organosilicon compounds |
| US5663398A (en) | 1996-05-17 | 1997-09-02 | Fmc Corporation | Processes for preparing functionalized alkyllithium compounds |
| US5696197A (en) | 1996-06-21 | 1997-12-09 | The Goodyear Tire & Rubber Company | Heterogeneous silica carbon black-filled rubber compound |
| US5663396A (en) | 1996-10-31 | 1997-09-02 | The Goodyear Tire & Rubber Company | Preparation of sulfur-containing organosilicon compounds |
| US5786441A (en) | 1996-12-31 | 1998-07-28 | Bridgestone Corporation | Polymers, elastomeric compounds and products thereof, derived from novel amine compounds containing side-chain organolithium moieties |
| US5684172A (en) | 1997-02-11 | 1997-11-04 | The Goodyear Tire & Rubber Company | Process for the preparation of organosilicon polysulfide compounds |
| US5684171A (en) | 1997-02-11 | 1997-11-04 | The Goodyear Tire & Rubber Company | Process for the preparation of organosilicon polysulfide compounds |
| US6525118B2 (en) | 1997-07-11 | 2003-02-25 | Bridgestone Corporation | Processability of silica-filled rubber stocks with reduced hysteresis |
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| JP2002179621A (ja) * | 2000-12-08 | 2002-06-26 | Adchemco Corp | 4−アセトキシスチレンの製造方法 |
| DE10295962T5 (de) | 2001-02-01 | 2004-04-22 | Fmc Corp. | Funktionalisierte Initiatoren für die anionische Polymerisation, geschützte funktionalisierte Polymere, deblockierte Analoga davon und Verfahren zur Herstellung derselben |
| DE60213380T2 (de) | 2001-02-28 | 2007-08-23 | Bridgestone Corp. | Kontinuierliches verfahren zur herstellung von engeren molekulargewichtverteilungen konjugierten dien-polymeren und dadurch hergestellten produkten |
| JP2003171422A (ja) | 2001-12-06 | 2003-06-20 | Toho Chem Ind Co Ltd | 共重合物およびその製造方法 |
| JP3797262B2 (ja) | 2002-04-05 | 2006-07-12 | 住友化学株式会社 | 変性ジエン系重合体ゴム、その製造方法及びゴム組成物 |
| US6770201B2 (en) * | 2002-08-07 | 2004-08-03 | Sandia National Laboratories | Cast-to-shape electrokinetic trapping medium |
| WO2004041870A2 (en) | 2002-10-30 | 2004-05-21 | Bridgestone Corporation | The use of sulfur containing initiators for anionic polymerization of monomers |
| EP1562630A4 (en) | 2002-10-31 | 2009-02-18 | Univ Northwestern | INJECTABLE BIOADHûSIVE POLYMERS HYDROGELES AND RELEVANT PROCESSES FOR ENZYMATIC PRODUCTION |
| US7056985B2 (en) | 2004-02-11 | 2006-06-06 | University Of Massachusetts Lowell | End-capped polymer chains and products thereof |
| US7226979B2 (en) | 2004-02-11 | 2007-06-05 | University Of Massachusetts Lowell | Copolymers comprising olefin and protected or unprotected hydroxystyrene units |
| CN100575372C (zh) | 2004-03-01 | 2009-12-30 | 株式会社普利司通 | 连续聚合反应器 |
| CN101090914B (zh) | 2004-10-26 | 2011-02-09 | 株式会社普利司通 | 具有连接基团的官能化聚合物 |
| US7816483B2 (en) | 2005-08-11 | 2010-10-19 | Bridgestone Corporation | Amine functionalized polymer |
| JP5079294B2 (ja) | 2005-10-04 | 2012-11-21 | 株式会社ブリヂストン | アミンで官能化されたポリマー |
| JP4934323B2 (ja) | 2006-02-07 | 2012-05-16 | 株式会社ブリヂストン | 変性天然ゴム及びその製造方法、並びにそれを用いたゴム組成物及びタイヤ |
| JP2009544806A (ja) | 2006-07-25 | 2009-12-17 | 株式会社ブリヂストン | 官能化ポリマー |
| KR101657603B1 (ko) | 2007-12-28 | 2016-09-19 | 가부시키가이샤 브리지스톤 | 히드록시아릴 관능화 중합체 |
| CN102625814B (zh) | 2009-06-30 | 2014-08-06 | 株式会社普利司通 | 用包含羟基的二苯基乙烯官能化的聚合物 |
| KR101727342B1 (ko) | 2009-06-30 | 2017-04-14 | 가부시키가이샤 브리지스톤 | 히드록시아릴 관능화 중합체 |
| JP5889787B2 (ja) | 2009-07-01 | 2016-03-22 | 株式会社ブリヂストン | フリーラジカル開始重合によるヒドロキシアリール官能化共重合体の製造方法 |
| US20130035437A1 (en) | 2010-02-28 | 2013-02-07 | Xiao-Dong Pan | Rubber compositions including siliceous fillers |
-
2010
- 2010-06-28 BR BRPI1015023A patent/BRPI1015023A2/pt active Search and Examination
- 2010-06-28 EP EP10800273.4A patent/EP2448900B1/en not_active Not-in-force
- 2010-06-28 CN CN201080038722.6A patent/CN102482186B/zh not_active Expired - Fee Related
- 2010-06-28 US US13/381,311 patent/US9365660B2/en not_active Expired - Fee Related
- 2010-06-28 KR KR1020127002323A patent/KR101752934B1/ko not_active Expired - Fee Related
- 2010-06-28 WO PCT/US2010/040242 patent/WO2011008501A2/en not_active Ceased
- 2010-06-28 ES ES10800273.4T patent/ES2633097T3/es active Active
- 2010-06-28 JP JP2012518567A patent/JP5792162B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2633097T3 (es) | 2017-09-19 |
| KR101752934B1 (ko) | 2017-07-03 |
| WO2011008501A4 (en) | 2011-06-03 |
| CN102482186A (zh) | 2012-05-30 |
| CN102482186B (zh) | 2015-09-30 |
| US9365660B2 (en) | 2016-06-14 |
| JP5792162B2 (ja) | 2015-10-07 |
| WO2011008501A2 (en) | 2011-01-20 |
| JP2012532132A (ja) | 2012-12-13 |
| WO2011008501A3 (en) | 2011-04-14 |
| EP2448900A4 (en) | 2014-07-23 |
| EP2448900B1 (en) | 2017-04-26 |
| KR20120046721A (ko) | 2012-05-10 |
| US20120136128A1 (en) | 2012-05-31 |
| EP2448900A2 (en) | 2012-05-09 |
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