BRPI1009860A8 - composto, uso do mesmo, composição farmacêutica e método para tratamento terapêutico ou prevenção de doenças em humanos ou animais - Google Patents
composto, uso do mesmo, composição farmacêutica e método para tratamento terapêutico ou prevenção de doenças em humanos ou animais Download PDFInfo
- Publication number
- BRPI1009860A8 BRPI1009860A8 BRPI1009860A BRPI1009860A BRPI1009860A8 BR PI1009860 A8 BRPI1009860 A8 BR PI1009860A8 BR PI1009860 A BRPI1009860 A BR PI1009860A BR PI1009860 A BRPI1009860 A BR PI1009860A BR PI1009860 A8 BRPI1009860 A8 BR PI1009860A8
- Authority
- BR
- Brazil
- Prior art keywords
- diseases
- prevention
- compound
- humans
- animals
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 241001465754 Metazoa Species 0.000 title 1
- 230000006806 disease prevention Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 150000002632 lipids Chemical class 0.000 abstract 3
- 229940053200 antiepileptics fatty acid derivative Drugs 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 239000012528 membrane Substances 0.000 abstract 2
- 210000000170 cell membrane Anatomy 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 235000013376 functional food Nutrition 0.000 abstract 1
- 239000002417 nutraceutical Substances 0.000 abstract 1
- 235000021436 nutraceutical agent Nutrition 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Emergency Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200900725A ES2345241B1 (es) | 2009-03-16 | 2009-03-16 | Uso de 2-hidroxiderivados de acidos grasos poliinsaturados como medicamentos. |
| PCT/ES2010/070153 WO2010106211A1 (es) | 2009-03-16 | 2010-03-15 | Uso de derivados de ácidos grasos poliinsaturados como medicamentos |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI1009860A2 BRPI1009860A2 (pt) | 2016-03-08 |
| BRPI1009860A8 true BRPI1009860A8 (pt) | 2019-12-17 |
Family
ID=42673244
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1009860A BRPI1009860A8 (pt) | 2009-03-16 | 2010-03-15 | composto, uso do mesmo, composição farmacêutica e método para tratamento terapêutico ou prevenção de doenças em humanos ou animais |
Country Status (19)
| Country | Link |
|---|---|
| US (7) | US9161928B2 (ja) |
| EP (2) | EP2409963B1 (ja) |
| JP (1) | JP5904592B2 (ja) |
| KR (4) | KR20180021931A (ja) |
| CN (4) | CN106349058B (ja) |
| AU (6) | AU2010224749B2 (ja) |
| BR (1) | BRPI1009860A8 (ja) |
| CA (1) | CA2754963C (ja) |
| CL (1) | CL2011002268A1 (ja) |
| DK (2) | DK3159329T3 (ja) |
| ES (3) | ES2345241B1 (ja) |
| HK (1) | HK1232207A1 (ja) |
| HU (2) | HUE051850T2 (ja) |
| MX (1) | MX2011009614A (ja) |
| PL (1) | PL2409963T3 (ja) |
| PT (2) | PT3159329T (ja) |
| RU (1) | RU2513995C2 (ja) |
| SI (1) | SI3159329T1 (ja) |
| WO (1) | WO2010106211A1 (ja) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2345241B1 (es) | 2009-03-16 | 2011-09-08 | Lipopharma Therapeutics | Uso de 2-hidroxiderivados de acidos grasos poliinsaturados como medicamentos. |
| JP5934102B2 (ja) | 2009-10-30 | 2016-06-15 | レトロトップ、 インコーポレイテッドＲｅｔｒｏｔｏｐｅ， Ｉｎｃ． | Ｐｕｆａ誘導体による酸化ストレス障害の緩和 |
| WO2012148926A2 (en) | 2011-04-26 | 2012-11-01 | Retrotope, Inc. | Neurodegenerative disorders and muscle diseases implicating pufas |
| CA2834343C (en) | 2011-04-26 | 2021-10-12 | Retrotope, Inc. | Disorders implicating pufa oxidation |
| JP6106158B2 (ja) | 2011-04-26 | 2017-03-29 | レトロトップ、 インコーポレイテッドＲｅｔｒｏｔｏｐｅ， Ｉｎｃ． | 酸化的網膜疾患 |
| CA2834342C (en) | 2011-04-26 | 2021-08-31 | Retrotope, Inc. | Impaired energy processing disorders and mitochondrial deficiency |
| ES2401629B1 (es) * | 2011-10-07 | 2014-03-04 | Universitat De Les Illes Balears | Enantiómeros de 2-hidroxiderivados de ácidos grasos y su uso como medicamentos. |
| KR101970151B1 (ko) | 2014-10-21 | 2019-04-19 | 유니버시다드 데 레스 일레스 발레아르스 | 하이드록시-트리글리세라이드의 합성 방법 및 질병의 예방 및 치료에 사용되는 하이드록시-트리글리세라이드의 용도 |
| EP3267200A4 (en) * | 2015-03-06 | 2018-08-22 | Niigata University | Biomarker of dementia with lewy bodies |
| EP3950649A1 (en) | 2015-11-23 | 2022-02-09 | Retrotope, Inc. | Site-specific isotopic labeling of 1, 4-diene systems |
| GB201521085D0 (en) * | 2015-11-30 | 2016-01-13 | Biozep As | Use |
| US11260042B2 (en) * | 2017-05-16 | 2022-03-01 | Ability Pharmaceuticals S.L. | Pharmaceutical combination for the treatment of cancer |
| US10596165B2 (en) | 2018-02-12 | 2020-03-24 | resTORbio, Inc. | Combination therapies |
| DK3813946T3 (da) | 2018-06-15 | 2024-08-19 | Janssen Pharmaceutica Nv | Rapamycin-analoger og anvendelser deraf |
| JP2023506410A (ja) | 2019-12-05 | 2023-02-16 | アナクリア セラピューティクス， インコーポレイテッド | ラパマイシン類似体及びその使用 |
| ES2846824B2 (es) * | 2020-01-29 | 2022-01-19 | Univ Illes Balears | Profarmacos de acidos grasos poliinsaturados y usos medicos de los mismos |
| CA3166307C (en) * | 2020-01-29 | 2024-05-21 | Pablo Vicente Escriba Ruiz | Alpha-hydroxylated fatty acid metabolites, medical uses of same and use as biomarkers |
| BR112022014074A2 (pt) | 2020-02-10 | 2022-09-13 | Ability Pharmaceuticals S L | Combinação farmacêutica para o tratamento de um câncer |
| EP4107163A4 (en) | 2020-02-21 | 2024-06-19 | Retrotope, Inc. | PROCESS FOR ISOTOPIC MODIFICATION OF POLYUNSATURATED FATTY ACIDS AND THEIR DERIVATIVES |
| US12109194B2 (en) | 2021-02-05 | 2024-10-08 | Biojiva Llc | Synergistic combination therapy for treating ALS |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8717816D0 (en) | 1987-07-28 | 1987-09-03 | Manchester Inst Science Tech | Fabric testing apparatus |
| GB2218984B (en) * | 1988-05-27 | 1992-09-23 | Renafield Limited | Process for preparing high-concentration mixtures of polyunsaturated fatty acids & their esters and their prophylactic or therapeutic uses |
| JPH05974A (ja) * | 1991-06-21 | 1993-01-08 | Sagami Chem Res Center | ハロゲン化不飽和アルキル化合物及びその前駆体 |
| ES2161146B1 (es) * | 1999-06-29 | 2002-07-01 | Consejo Superior Investigacion | Compuestos antimicrobianos, uso y metodo para inducir resistencia a infecciones de bacterias en plantas. |
| US6344574B1 (en) | 2000-07-20 | 2002-02-05 | The United States Of America As Represented By The Secretary Of Agriculture | Solvent fractionation of chicken fat for making lipid compositions enriched in unsaturated fatty acid-containing triacylglycerols |
| DE10106660A1 (de) * | 2001-02-12 | 2002-08-29 | Celanese Ventures Gmbh | Verfahren zur Herstellung von gamma-Linolensäure aus einer Ciliaten-Kultur durch Zusatz geeigneter Vorläufermoleküle zu dem Kulturmedium |
| ES2186576B1 (es) * | 2001-10-11 | 2004-09-16 | Universitat De Les Illes Balears | Acido 2-hidroxioleico para utilizar como medicamento. |
| WO2003084305A2 (en) * | 2002-04-01 | 2003-10-16 | University Of Southern California | Trihydroxy polyunsaturated eicosanoids |
| US7135575B2 (en) * | 2003-03-03 | 2006-11-14 | Array Biopharma, Inc. | P38 inhibitors and methods of use thereof |
| US7884131B2 (en) * | 2004-11-19 | 2011-02-08 | Martek Biosciences, Corporation | Oxylipins from long chain polyunsaturated fatty acids and methods of making and using the same |
| GB0428384D0 (en) * | 2004-12-24 | 2005-02-02 | Sla Pharma Ag | Eicosapentaenoic acid |
| US8324276B2 (en) * | 2005-01-24 | 2012-12-04 | Pronova Biopharma Norge As | Fatty acid composition for treatment of alzheimer's disease and cognitive dysfunction |
| CN101213281B (zh) * | 2005-05-04 | 2013-03-13 | 普罗诺瓦生物医药挪威公司 | 新的dha衍生物及其作为药物的用途 |
| CA2607247C (en) | 2005-05-04 | 2015-10-06 | Pronova Biopharma Norge As | .alpha.-substituted dha derivatives |
| US8059805B2 (en) * | 2005-06-30 | 2011-11-15 | Emc Corporation | Enhanced services provided using communication redirection and processing |
| CN103211807A (zh) | 2005-07-08 | 2013-07-24 | Dsmip资产公司 | 用于治疗痴呆和前痴呆相关病症的多不饱和脂肪酸 |
| EP1772146A1 (en) * | 2005-10-03 | 2007-04-11 | Neuropharma, S.A. | Polyunsaturated fatty acids as bace inhibitors |
| WO2007058523A1 (en) * | 2005-11-17 | 2007-05-24 | N.V. Nutricia | Composition with docosapentaenoic acid |
| ATE509624T1 (de) | 2005-12-23 | 2011-06-15 | Nutricia Nv | Zusammensetzung enthaltend mehrfach ungesättigte fettsäuren, proteine, mangan und/oder molybden und nukleotide/nukleoside, zur behandlung von demenz |
| JP2010508262A (ja) | 2006-11-01 | 2010-03-18 | プロノヴァ バイオファーマ ノルゲ アーエス | 組成物 |
| US8399516B2 (en) * | 2006-11-01 | 2013-03-19 | Pronova Biopharma Norge As | Alpha-substituted omega-3 lipids that are activators or modulators of the peroxisome proliferators-activated receptor (PPAR) |
| WO2008053340A1 (en) * | 2006-11-03 | 2008-05-08 | Pronova Biopharma Norge As | A combination product comprising at least one lipid substituted in the alpha position and at least one hypoglycemic agent |
| US20080234377A1 (en) * | 2007-03-23 | 2008-09-25 | Martek Biosciences Corporation | Polyunsaturated fatty acids for treatment of dementia and pre-dementia-related conditions |
| ES2345241B1 (es) | 2009-03-16 | 2011-09-08 | Lipopharma Therapeutics | Uso de 2-hidroxiderivados de acidos grasos poliinsaturados como medicamentos. |
| ES2401629B1 (es) * | 2011-10-07 | 2014-03-04 | Universitat De Les Illes Balears | Enantiómeros de 2-hidroxiderivados de ácidos grasos y su uso como medicamentos. |
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2009
- 2009-03-16 ES ES200900725A patent/ES2345241B1/es active Active
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2010
- 2010-03-15 PL PL10753158T patent/PL2409963T3/pl unknown
- 2010-03-15 CN CN201610773061.0A patent/CN106349058B/zh active Active
- 2010-03-15 CN CN201610773030.5A patent/CN106420686B/zh active Active
- 2010-03-15 ES ES10753158.4T patent/ES2613606T3/es active Active
- 2010-03-15 US US13/257,128 patent/US9161928B2/en active Active
- 2010-03-15 CA CA2754963A patent/CA2754963C/en active Active
- 2010-03-15 SI SI201032041T patent/SI3159329T1/sl unknown
- 2010-03-15 AU AU2010224749A patent/AU2010224749B2/en not_active Revoked
- 2010-03-15 KR KR1020187005245A patent/KR20180021931A/ko not_active Application Discontinuation
- 2010-03-15 MX MX2011009614A patent/MX2011009614A/es active IP Right Grant
- 2010-03-15 DK DK16201132.4T patent/DK3159329T3/da active
- 2010-03-15 RU RU2011141850/04A patent/RU2513995C2/ru active
- 2010-03-15 BR BRPI1009860A patent/BRPI1009860A8/pt not_active Application Discontinuation
- 2010-03-15 CN CN2010800119398A patent/CN102356057A/zh active Pending
- 2010-03-15 KR KR1020197004239A patent/KR20190018754A/ko active Search and Examination
- 2010-03-15 HU HUE16201132A patent/HUE051850T2/hu unknown
- 2010-03-15 EP EP10753158.4A patent/EP2409963B1/en active Active
- 2010-03-15 JP JP2012500281A patent/JP5904592B2/ja active Active
- 2010-03-15 PT PT162011324T patent/PT3159329T/pt unknown
- 2010-03-15 HU HUE10753158A patent/HUE032027T2/en unknown
- 2010-03-15 WO PCT/ES2010/070153 patent/WO2010106211A1/es active Application Filing
- 2010-03-15 ES ES16201132T patent/ES2820025T3/es active Active
- 2010-03-15 KR KR1020207005917A patent/KR102233102B1/ko active IP Right Grant
- 2010-03-15 EP EP16201132.4A patent/EP3159329B1/en active Active
- 2010-03-15 DK DK10753158.4T patent/DK2409963T3/en active
- 2010-03-15 KR KR1020117024210A patent/KR101833772B1/ko active IP Right Grant
- 2010-03-15 PT PT107531584T patent/PT2409963T/pt unknown
- 2010-03-15 CN CN201910095352.2A patent/CN109999018A/zh active Pending
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2011
- 2011-09-13 CL CL2011002268A patent/CL2011002268A1/es unknown
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2015
- 2015-09-29 US US14/869,045 patent/US9763906B2/en active Active
- 2015-09-29 US US14/869,080 patent/US9763907B2/en active Active
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2016
- 2016-07-13 US US15/209,540 patent/US9907772B2/en active Active
- 2016-10-07 AU AU2016238970A patent/AU2016238970B2/en not_active Revoked
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2017
- 2017-06-02 HK HK17105487.0A patent/HK1232207A1/zh unknown
- 2017-08-22 US US15/683,379 patent/US10201515B2/en active Active
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2018
- 2018-06-05 AU AU2018203976A patent/AU2018203976B2/en not_active Expired - Fee Related
- 2018-12-18 US US16/224,262 patent/US20190365690A1/en not_active Abandoned
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2019
- 2019-09-06 AU AU2019226257A patent/AU2019226257B2/en active Active
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2020
- 2020-04-22 US US16/855,463 patent/US11253497B2/en active Active
- 2020-07-13 AU AU2020205214A patent/AU2020205214B2/en active Active
- 2020-07-13 AU AU2020205213A patent/AU2020205213B2/en active Active
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