BR112017017840A2 - composição compreendendo sialil-lactose para uso na melhora das capacidades de aprendizado e função de memória - Google Patents
composição compreendendo sialil-lactose para uso na melhora das capacidades de aprendizado e função de memóriaInfo
- Publication number
- BR112017017840A2 BR112017017840A2 BR112017017840A BR112017017840A BR112017017840A2 BR 112017017840 A2 BR112017017840 A2 BR 112017017840A2 BR 112017017840 A BR112017017840 A BR 112017017840A BR 112017017840 A BR112017017840 A BR 112017017840A BR 112017017840 A2 BR112017017840 A2 BR 112017017840A2
- Authority
- BR
- Brazil
- Prior art keywords
- sialyl lactose
- memory function
- composition
- learning abilities
- improving learning
- Prior art date
Links
- 230000006386 memory function Effects 0.000 title abstract 2
- OIZGSVFYNBZVIK-FHHHURIISA-N 3'-sialyllactose Chemical compound O1[C@@H]([C@H](O)[C@H](O)CO)[C@H](NC(=O)C)[C@@H](O)C[C@@]1(C(O)=O)O[C@@H]1[C@@H](O)[C@H](O[C@H]([C@H](O)CO)[C@H](O)[C@@H](O)C=O)O[C@H](CO)[C@@H]1O OIZGSVFYNBZVIK-FHHHURIISA-N 0.000 title 1
- 235000016709 nutrition Nutrition 0.000 abstract 2
- TYALNJQZQRNQNQ-UHFFFAOYSA-N #alpha;2,6-sialyllactose Natural products O1C(C(O)C(O)CO)C(NC(=O)C)C(O)CC1(C(O)=O)OCC1C(O)C(O)C(O)C(OC2C(C(O)C(O)OC2CO)O)O1 TYALNJQZQRNQNQ-UHFFFAOYSA-N 0.000 abstract 1
- CILYIEBUXJIHCO-UHFFFAOYSA-N 102778-91-6 Natural products O1C(C(O)C(O)CO)C(NC(=O)C)C(O)CC1(C(O)=O)OC1C(O)C(OC2C(C(O)C(O)OC2CO)O)OC(CO)C1O CILYIEBUXJIHCO-UHFFFAOYSA-N 0.000 abstract 1
- DVGKRPYUFRZAQW-UHFFFAOYSA-N 3 prime Natural products CC(=O)NC1OC(CC(O)C1C(O)C(O)CO)(OC2C(O)C(CO)OC(OC3C(O)C(O)C(O)OC3CO)C2O)C(=O)O DVGKRPYUFRZAQW-UHFFFAOYSA-N 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- CILYIEBUXJIHCO-UITFWXMXSA-N N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucose Chemical compound O1[C@@H]([C@H](O)[C@H](O)CO)[C@H](NC(=O)C)[C@@H](O)C[C@@]1(C(O)=O)O[C@@H]1[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O)[C@H](O)O[C@@H]2CO)O)O[C@H](CO)[C@@H]1O CILYIEBUXJIHCO-UITFWXMXSA-N 0.000 abstract 1
- OIZGSVFYNBZVIK-UHFFFAOYSA-N N-acetylneuraminosyl-D-lactose Natural products O1C(C(O)C(O)CO)C(NC(=O)C)C(O)CC1(C(O)=O)OC1C(O)C(OC(C(O)CO)C(O)C(O)C=O)OC(CO)C1O OIZGSVFYNBZVIK-UHFFFAOYSA-N 0.000 abstract 1
- TYALNJQZQRNQNQ-JLYOMPFMSA-N alpha-Neup5Ac-(2->6)-beta-D-Galp-(1->4)-beta-D-Glcp Chemical compound O1[C@@H]([C@H](O)[C@H](O)CO)[C@H](NC(=O)C)[C@@H](O)C[C@@]1(C(O)=O)OC[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O)[C@H](O)O[C@@H]2CO)O)O1 TYALNJQZQRNQNQ-JLYOMPFMSA-N 0.000 abstract 1
- SQVRNKJHWKZAKO-UHFFFAOYSA-N beta-N-Acetyl-D-neuraminic acid Natural products CC(=O)NC1C(O)CC(O)(C(O)=O)OC1C(O)C(O)CO SQVRNKJHWKZAKO-UHFFFAOYSA-N 0.000 abstract 1
- 210000004556 brain Anatomy 0.000 abstract 1
- 230000008133 cognitive development Effects 0.000 abstract 1
- 229920001542 oligosaccharide Polymers 0.000 abstract 1
- 150000002482 oligosaccharides Chemical class 0.000 abstract 1
- SQVRNKJHWKZAKO-OQPLDHBCSA-N sialic acid Chemical compound CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)OC1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-OQPLDHBCSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/04—Disaccharides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Pediatric Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Silicon Polymers (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Saccharide Compounds (AREA)
Abstract
a presente invenção refere-se ao uso de uma composição nutricional que compreende oligossacarídeos sialilados para melhorar o desenvolvimento cognitivo e as capacidades de aprendizado em mamíferos. a composição nutricional compreende 3'-sialil-lactose (3'-sl) e 6'-sialil-lactose (6'-sl) em uma razão em peso entre 10:1 e 1:10 e é especificamente para uso na melhora da capacidade de aprendizado e/ou na melhora da função de memória de um indivíduo através do aumento da concentração de ácido siálico (neu5ac) no cérebro do dito indivíduo.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CN2015/074457 WO2016145628A1 (en) | 2015-03-18 | 2015-03-18 | Composition comprising siallyllactose for use in enhancing learning skills and memory function |
| CNPCT/CN2015/074457 | 2015-03-18 | ||
| PCT/EP2016/055890 WO2016146789A1 (en) | 2015-03-18 | 2016-03-17 | Compostion comprising siallyllactose for use in enhancing learning skills and memory function |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112017017840A2 true BR112017017840A2 (pt) | 2018-04-10 |
| BR112017017840B1 BR112017017840B1 (pt) | 2022-10-25 |
Family
ID=56918404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112017017840-0A BR112017017840B1 (pt) | 2015-03-18 | 2016-03-17 | Composição nutricional, bem como uso de 3'-sialil lactose (3'-sl) e 6'-sialil-lactose (6'-sl) |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US11528928B2 (pt) |
| EP (1) | EP3270714A1 (pt) |
| CN (1) | CN107427057A (pt) |
| AU (2) | AU2016232084A1 (pt) |
| BR (1) | BR112017017840B1 (pt) |
| CL (1) | CL2017002184A1 (pt) |
| MX (2) | MX2017011498A (pt) |
| MY (1) | MY197396A (pt) |
| PH (1) | PH12017550052A1 (pt) |
| RU (1) | RU2770223C2 (pt) |
| WO (2) | WO2016145628A1 (pt) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7125348B2 (ja) * | 2016-01-13 | 2022-08-24 | ベネバイオシス カンパニー リミテッド | ＰＧＣ－１αの発現を増加させる組成物 |
| CA3030809A1 (en) | 2016-07-28 | 2018-02-01 | Fonterra Co-Operative Group Limited | Sialyloligosaccharide product and process |
| EP3629770A1 (en) * | 2017-05-24 | 2020-04-08 | Société des Produits Nestlé S.A. | Composition comprising oligofructose (of) for use in the improvement of short term memory and other cognitive benefits |
| AU2018272156B2 (en) | 2017-05-24 | 2024-05-30 | Societe Des Produits Nestle S.A. | A nutritional composition for use to enhance attention and/or reduce impulsivity |
| AU2018274636B2 (en) * | 2017-05-24 | 2024-05-02 | Societe Des Produits Nestle S.A. | Composition comprising Human Milk Oligosaccharides (HMO) for use in the improvement of short term memory and other cognitive benefits |
| US11701404B2 (en) | 2017-12-01 | 2023-07-18 | Societe Des Produits Nestle S.A. | Human milk fortifier composition |
| US20210267252A1 (en) * | 2018-06-25 | 2021-09-02 | Societe Des Produits Nestle S.A. | Composition comprising human milk oligosaccharides for use in improving, enhancing, promoting or modulating a serotonergic function in the central nervous system |
| CN112218546B (zh) * | 2018-06-25 | 2024-05-24 | 雀巢产品有限公司 | 包含用于改善、增强、促进或调节中枢神经系统中gaba能功能的人乳低聚糖的组合物 |
| CN108835262B (zh) * | 2018-07-19 | 2021-08-27 | 澳优乳业（中国）有限公司 | 一种改善记忆力的调制乳粉及其制备方法 |
| EP3934656A1 (en) * | 2019-03-05 | 2022-01-12 | Société des Produits Nestlé S.A. | A nutritional composition for use to enhance executive function |
| US20220160013A1 (en) * | 2019-03-05 | 2022-05-26 | Glycom A/S | Human milk oligosaccharides for use in enhancing executive function |
| WO2020259540A1 (zh) * | 2019-06-25 | 2020-12-30 | 嘉必优生物技术（武汉）股份有限公司 | 唾液酸类化合物在制备治疗脑部退行性病变药物或营养添加剂或食品中的应用 |
| EP4072321A1 (en) * | 2019-12-09 | 2022-10-19 | Société des Produits Nestlé S.A. | Compositions comprising human milk oligosaccharides for use in a subject to support language development |
| CN111387284A (zh) * | 2020-04-28 | 2020-07-10 | 江苏集萃工业生物技术研究所有限公司 | 一种燕窝酸牛奶及其制备方法 |
| CN114487255A (zh) * | 2020-10-23 | 2022-05-13 | 内蒙古伊利实业集团股份有限公司 | 一种乳粉或乳清粉中唾液酸含量的检测方法 |
| EP4313064A1 (en) * | 2021-03-22 | 2024-02-07 | Société des Produits Nestlé S.A. | Human milk oligosaccharides |
| CN116189909B (zh) * | 2023-03-06 | 2024-02-20 | 佳木斯大学 | 基于推举算法的临床医学判别方法及系统 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19701382A1 (de) * | 1997-01-16 | 1998-07-23 | Nutricia Nv | Kohlenhydratmischung |
| US6630452B2 (en) * | 2000-02-17 | 2003-10-07 | Wyeth | Nutritional formulation containing prebiotic substances |
| US7867541B2 (en) * | 2003-04-14 | 2011-01-11 | Mead Johnson Nutrition Company | Compositions and methods of formulation for enteral formulas containing sialic acid |
| US20060247153A1 (en) | 2005-04-29 | 2006-11-02 | Mcmahon Robert J | Method of improving learning and memory in mammals |
| EP2060257A1 (en) * | 2007-11-08 | 2009-05-20 | Nestec S.A. | Prevention and treatment of secondary infections following viral infection |
| NZ602370A (en) | 2010-03-12 | 2014-11-28 | Dsm Ip Assets Bv | Maternal sialic acid supplementation |
| EP2775852B1 (en) * | 2011-10-18 | 2016-08-17 | Nestec S.A. | Composition for use in brain growth and/or cognitive and/or psychomotor development |
| EP2880993A1 (en) * | 2013-12-04 | 2015-06-10 | Abbott Laboratories | Method of achieving memory and learning improvement by the administration of sialic acid |
| US20150305384A1 (en) | 2014-04-25 | 2015-10-29 | Mead Johnson Nutrition Company | Pediatric nutritional composition with human milk oligosaccahrides, prebiotics and probiotics |
-
2015
- 2015-03-18 WO PCT/CN2015/074457 patent/WO2016145628A1/en active Application Filing
-
2016
- 2016-03-17 US US15/558,339 patent/US11528928B2/en active Active
- 2016-03-17 EP EP16711580.7A patent/EP3270714A1/en active Pending
- 2016-03-17 RU RU2017135296A patent/RU2770223C2/ru active
- 2016-03-17 BR BR112017017840-0A patent/BR112017017840B1/pt active IP Right Grant
- 2016-03-17 MY MYPI2017702641A patent/MY197396A/en unknown
- 2016-03-17 CN CN201680013894.5A patent/CN107427057A/zh active Pending
- 2016-03-17 MX MX2017011498A patent/MX2017011498A/es unknown
- 2016-03-17 AU AU2016232084A patent/AU2016232084A1/en not_active Abandoned
- 2016-03-17 WO PCT/EP2016/055890 patent/WO2016146789A1/en active Application Filing
-
2017
- 2017-07-26 PH PH12017550052A patent/PH12017550052A1/en unknown
- 2017-08-28 CL CL2017002184A patent/CL2017002184A1/es unknown
- 2017-09-07 MX MX2023005755A patent/MX2023005755A/es unknown
-
2020
- 2020-09-11 AU AU2020230318A patent/AU2020230318B2/en active Active
-
2022
- 2022-12-07 US US18/077,176 patent/US20230095436A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2016146789A1 (en) | 2016-09-22 |
| MX2023005755A (es) | 2023-06-08 |
| AU2020230318A1 (en) | 2020-10-01 |
| MX2017011498A (es) | 2018-01-11 |
| PH12017550052A1 (en) | 2018-01-29 |
| AU2020230318B2 (en) | 2022-12-01 |
| US20230095436A1 (en) | 2023-03-30 |
| AU2016232084A1 (en) | 2017-08-10 |
| EP3270714A1 (en) | 2018-01-24 |
| US11528928B2 (en) | 2022-12-20 |
| RU2017135296A3 (pt) | 2019-09-10 |
| US20180064152A1 (en) | 2018-03-08 |
| CN107427057A (zh) | 2017-12-01 |
| WO2016145628A1 (en) | 2016-09-22 |
| BR112017017840B1 (pt) | 2022-10-25 |
| CL2017002184A1 (es) | 2018-05-04 |
| RU2770223C2 (ru) | 2022-04-14 |
| MY197396A (en) | 2023-06-15 |
| RU2017135296A (ru) | 2019-04-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B25A | Requested transfer of rights approved |
Owner name: SOCIETE DES PRODUITS NESTLE S.A. (CH) |
|
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B09W | Correction of the decision to grant [chapter 9.1.4 patent gazette] |
Free format text: RETIFICA-SE O DEFERIMENTO DA RPI 2692 DE 09/08/2022 POR TER SIDO EFETUADO COM INCORRECAO. |
|
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 17/03/2016, OBSERVADAS AS CONDICOES LEGAIS |