BRPI0922972A2 - Processo de preparo de ésteres ativados. - Google Patents

Processo de preparo de ésteres ativados.

Info

Publication number
BRPI0922972A2
BRPI0922972A2 BRPI0922972-8A BRPI0922972A BRPI0922972A2 BR PI0922972 A2 BRPI0922972 A2 BR PI0922972A2 BR PI0922972 A BRPI0922972 A BR PI0922972A BR PI0922972 A2 BRPI0922972 A2 BR PI0922972A2
Authority
BR
Brazil
Prior art keywords
preparation
activated esters
esters
activated
Prior art date
Application number
BRPI0922972-8A
Other languages
English (en)
Inventor
Antony Bigot
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of BRPI0922972A2 publication Critical patent/BRPI0922972A2/pt
Publication of BRPI0922972A8 publication Critical patent/BRPI0922972A8/pt
Publication of BRPI0922972B1 publication Critical patent/BRPI0922972B1/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36Oxygen or sulfur atoms
    • C07D207/402,5-Pyrrolidine-diones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/70Sulfur atoms
    • C07D213/71Sulfur atoms to which a second hetero atom is attached
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BRPI0922972-8A 2008-12-17 2009-12-15 Processo de preparação de ésteres ativados, bem como sal de diciclohexilamina BRPI0922972B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR08/07090 2008-12-17
FR0807090A FR2939795B1 (fr) 2008-12-17 2008-12-17 Procede de preparation d'esters actives
PCT/FR2009/052528 WO2010076474A1 (fr) 2008-12-17 2009-12-15 Procede de preparation d'esters actives

Publications (3)

Publication Number Publication Date
BRPI0922972A2 true BRPI0922972A2 (pt) 2015-08-11
BRPI0922972A8 BRPI0922972A8 (pt) 2018-02-06
BRPI0922972B1 BRPI0922972B1 (pt) 2021-06-01

Family

ID=40614691

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0922972-8A BRPI0922972B1 (pt) 2008-12-17 2009-12-15 Processo de preparação de ésteres ativados, bem como sal de diciclohexilamina

Country Status (26)

Country Link
US (1) US8314244B2 (pt)
EP (1) EP2379501B1 (pt)
JP (1) JP5467111B2 (pt)
KR (1) KR101645051B1 (pt)
CN (1) CN102292318B (pt)
AU (1) AU2009334689B2 (pt)
BR (1) BRPI0922972B1 (pt)
CA (1) CA2747105C (pt)
CY (1) CY1115035T1 (pt)
DK (1) DK2379501T3 (pt)
ES (1) ES2459918T3 (pt)
FR (1) FR2939795B1 (pt)
HK (1) HK1163664A1 (pt)
HR (1) HRP20140368T1 (pt)
IL (1) IL213525A (pt)
ME (1) ME01827B (pt)
MX (1) MX2011006624A (pt)
MY (1) MY156761A (pt)
PL (1) PL2379501T4 (pt)
PT (1) PT2379501E (pt)
RS (1) RS53267B (pt)
RU (1) RU2506258C2 (pt)
SG (1) SG172179A1 (pt)
SI (1) SI2379501T1 (pt)
SM (1) SMT201400061B (pt)
WO (1) WO2010076474A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2963007B1 (fr) 2010-07-26 2013-04-05 Sanofi Aventis Derives anticancereux, leur preparation et leur application therapeutique
US11352325B2 (en) 2011-09-28 2022-06-07 Waters Technologies Corporation Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals
US10436790B2 (en) 2011-09-28 2019-10-08 Waters Technologies Corporation Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals
WO2016069764A1 (en) 2014-10-30 2016-05-06 Waters Technologies Corporation Methods for the rapid preparation of labeled glycosylamines and for the analysis of glycosylated biomolecules producing the same
EP3218352B1 (en) 2014-11-13 2020-08-05 Waters Technologies Corporation Method for liquid chromatography calibration for labeled n-glycans, method for preparing a dextran ladder calibrant and calibrant
EP3472621A4 (en) 2016-06-21 2020-03-04 Waters Technologies Corporation ELECTRONIZED IONIZATION METHODS OF HIGHLY BASIC AMPHIPATHIC FRAGMENT MODIFIED GLYCANES
US11061023B2 (en) 2016-06-21 2021-07-13 Waters Technologies Corporation Fluorescence tagging of glycans and other biomolecules through reductive amination for enhanced MS signals
CN114839302A (zh) 2016-07-01 2022-08-02 沃特世科技公司 使用分子量截留过滤和过滤器上去糖基化从复杂基质快速制备标记的葡基胺的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5710101B2 (pt) * 1972-10-24 1982-02-24
US5872261A (en) 1997-09-18 1999-02-16 Pierce Chemical Company Preparation of sulfo-N- hydroxy succinimide salts with intermediate formation of diester
US5892057A (en) 1997-09-18 1999-04-06 Pierce Chemical Company Preparation of sulfo-N-hydroxysuccinimide salts
JP2002316987A (ja) * 2001-04-20 2002-10-31 Sankyo Co Ltd 2−アルコキシベンゼン誘導体を含有する医薬
DE60336149D1 (de) * 2002-08-16 2011-04-07 Immunogen Inc Vernetzer mit hoher reaktivität und löslichkeit und ihre verwendung bei der herstellung von konjugaten für die gezielte abgabe von kleinmolekularen arzneimitteln
WO2006054426A1 (ja) * 2004-10-29 2006-05-26 National University Corporation Toyama University 高蛍光量子収率型疎水性蛍光プローブ、それを用いる生体高分子検出法ならびに生体高分子間相互作用検出法
US7723399B2 (en) * 2004-11-09 2010-05-25 Ciba Specialty Chemicals Corporation N-substituted imides as polymerization initiators
US8871720B2 (en) * 2005-07-07 2014-10-28 Seattle Genetics, Inc. Monomethylvaline compounds having phenylalanine carboxy modifications at the C-terminus

Also Published As

Publication number Publication date
FR2939795A1 (fr) 2010-06-18
SMT201400061B (it) 2014-07-07
PL2379501T4 (pl) 2014-12-31
RS53267B (en) 2014-08-29
FR2939795B1 (fr) 2010-12-17
RU2506258C2 (ru) 2014-02-10
JP2012512234A (ja) 2012-05-31
WO2010076474A1 (fr) 2010-07-08
AU2009334689B2 (en) 2015-10-08
HRP20140368T1 (hr) 2014-06-20
US8314244B2 (en) 2012-11-20
SG172179A1 (en) 2011-07-28
CN102292318B (zh) 2014-01-01
CN102292318A (zh) 2011-12-21
MY156761A (en) 2016-03-31
BRPI0922972B1 (pt) 2021-06-01
EP2379501B1 (fr) 2014-01-22
MX2011006624A (es) 2011-11-04
US20110313168A1 (en) 2011-12-22
JP5467111B2 (ja) 2014-04-09
BRPI0922972A8 (pt) 2018-02-06
IL213525A0 (en) 2011-07-31
EP2379501A1 (fr) 2011-10-26
CA2747105C (fr) 2017-02-28
CA2747105A1 (fr) 2010-07-08
KR101645051B1 (ko) 2016-08-02
HK1163664A1 (en) 2012-09-14
ME01827B (me) 2014-12-20
ES2459918T3 (es) 2014-05-12
DK2379501T3 (da) 2014-04-28
RU2011129652A (ru) 2013-01-27
PL2379501T3 (pl) 2014-07-31
AU2009334689A1 (en) 2011-07-07
SI2379501T1 (sl) 2014-05-30
PT2379501E (pt) 2014-05-02
IL213525A (en) 2014-11-30
KR20110094311A (ko) 2011-08-23
CY1115035T1 (el) 2016-12-14

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Legal Events

Date Code Title Description
B25G Requested change of headquarter approved

Owner name: SANOFI (FR)

B25A Requested transfer of rights approved

Owner name: IMMONUGEN, INC. (US)

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 15/12/2009, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF