BRPI0909627A2 - métodos, composições e kits para tratar dores e pruridos - Google Patents

métodos, composições e kits para tratar dores e pruridos

Info

Publication number
BRPI0909627A2
BRPI0909627A2 BRPI0909627A BRPI0909627A BRPI0909627A2 BR PI0909627 A2 BRPI0909627 A2 BR PI0909627A2 BR PI0909627 A BRPI0909627 A BR PI0909627A BR PI0909627 A BRPI0909627 A BR PI0909627A BR PI0909627 A2 BRPI0909627 A2 BR PI0909627A2
Authority
BR
Brazil
Prior art keywords
itching
kits
compositions
methods
treating pain
Prior art date
Application number
BRPI0909627A
Other languages
English (en)
Portuguese (pt)
Inventor
P Bean Bruce
J Woolf Clifford
Original Assignee
Harvard College
Massachusetts Gen Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College, Massachusetts Gen Hospital filed Critical Harvard College
Publication of BRPI0909627A2 publication Critical patent/BRPI0909627A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BRPI0909627A 2008-03-11 2009-03-11 métodos, composições e kits para tratar dores e pruridos BRPI0909627A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6901808P 2008-03-11 2008-03-11
PCT/US2009/001541 WO2009114139A2 (en) 2008-03-11 2009-03-11 Methods, compositions, and kits for treating pain and pruritis

Publications (1)

Publication Number Publication Date
BRPI0909627A2 true BRPI0909627A2 (pt) 2018-04-10

Family

ID=41065720

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0909627A BRPI0909627A2 (pt) 2008-03-11 2009-03-11 métodos, composições e kits para tratar dores e pruridos

Country Status (11)

Country Link
US (1) US20110086818A1 (enExample)
EP (1) EP2271329A4 (enExample)
JP (1) JP2011513484A (enExample)
KR (1) KR20110044166A (enExample)
CN (1) CN102112121A (enExample)
AU (1) AU2009223739A1 (enExample)
BR (1) BRPI0909627A2 (enExample)
CA (1) CA2717042A1 (enExample)
IL (1) IL208027A0 (enExample)
MX (1) MX2010009951A (enExample)
WO (1) WO2009114139A2 (enExample)

Families Citing this family (32)

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Publication number Priority date Publication date Assignee Title
JP2010510227A (ja) 2006-11-20 2010-04-02 プレジデント アンド フェロウズ オブ ハーバード カレッジ 痛みおよび痒みの治療方法、組成物およびキット
US8637577B2 (en) 2009-01-22 2014-01-28 Absorption Pharmaceuticals, LLC Desensitizing drug product
JP6205133B2 (ja) * 2009-07-10 2017-09-27 プレジデント アンド フェローズ オブ ハーバード カレッジ 抗炎症剤としての恒久的に荷電したナトリウムおよびカルシウムチャンネルブロッカー
JP5832856B2 (ja) * 2010-12-15 2015-12-16 久光製薬株式会社 局所鎮痛作用増強剤及び局所鎮痛キット
US8865741B2 (en) 2011-02-18 2014-10-21 Asana Biosciences, Llc Aminoindane compounds and use thereof in treating pain
EP2771320B1 (en) 2011-10-24 2016-06-22 Endo Pharmaceuticals Inc. Cyclohexylamines
US8779003B2 (en) 2011-12-29 2014-07-15 Mackay Memorial Hospital Method and composition for prolonging analgesic effect of local anesthetic
WO2014028675A1 (en) 2012-08-15 2014-02-20 Endo Pharmaceuticals Inc. Use of aminoindane compounds in treating overactive bladder and interstitial cystitis
CN111557432B (zh) 2013-02-08 2023-08-04 通用磨坊公司 低钠食品
EA201692060A1 (ru) * 2014-04-14 2017-02-28 Флекс Фарма, Инк. Активаторы ионного канала и способы их применения
RU2018107695A (ru) 2015-08-03 2019-09-05 Президент Энд Феллоуз Оф Гарвард Колледж Заряженные блокаторы ионных каналов и способы их применения
CN106214678B (zh) * 2016-07-26 2020-12-29 上海璃道医药科技有限公司 苯酮类药物的用途
WO2018136943A1 (en) 2017-01-23 2018-07-26 Flex Pharma, Inc. Compositions and methods affecting exercise performance
KR101877002B1 (ko) * 2017-03-06 2018-07-12 서울대학교 산학협력단 피라졸 유도체를 유효성분으로 함유하는 소양증의 예방 또는 치료용 약학적 조성물 및 이를 검출하기 위한 스크리닝 방법
KR101867779B1 (ko) * 2017-12-08 2018-06-19 서울대학교산학협력단 피라졸 유도체를 유효성분으로 함유하는 소양증의 예방 또는 치료용 약학적 조성물 및 이를 검출하기 위한 스크리닝 방법
WO2019144139A1 (en) * 2018-01-22 2019-07-25 Oregon State University Immunogenic compositions comprising mycobacterium bovis surface proteins and uses thereof
WO2019173394A1 (en) 2018-03-05 2019-09-12 Wylder Nation Foundation Compositions and methods for activating signaling through the cb1 cannabinoid receptor for treating and preventing diseases and disorders characterized by abnormal cellular accumulation of sphingolipids such as sphingomyelin
MX2021001351A (es) * 2018-08-15 2021-04-13 Pharmacyl Ab Benzamidas sustituidas y su uso en terapia.
CN109498604A (zh) * 2018-12-24 2019-03-22 复旦大学 香叶醇新用途,预防和治疗非疾病引起的瘙痒症的配制品及方法
BR112021017809A2 (pt) 2019-03-11 2021-11-23 Nocion Therapeutics Inc Bloqueadores de canais iônicos substituídos por éster e métodos para uso
US10786485B1 (en) 2019-03-11 2020-09-29 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
JP7692834B2 (ja) 2019-03-11 2025-06-16 ノシオン セラピューティクス,インコーポレイテッド 荷電したイオンチャンネル遮断薬および使用方法
BR112021017772A2 (pt) 2019-03-11 2021-11-16 Nocion Therapeutics Inc Bloqueadores de canais de íons carregados e métodos para uso
US10780083B1 (en) 2019-03-11 2020-09-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
JP7513713B2 (ja) 2019-11-06 2024-07-09 ノシオン セラピューティクス,インコーポレイテッド 荷電したイオンチャンネル遮断薬および使用方法
AU2020380118A1 (en) 2019-11-06 2022-05-19 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US20230165812A1 (en) * 2020-02-27 2023-06-01 President And Fellows Of Harvard College Nociceptor neurons control cancer immunosurveillance
JP2023515874A (ja) * 2020-03-04 2023-04-14 ノイキュアズ,インコーポレーテッド Trpv1調節物質の投与に関連する交感神経興奮を防止するためのqx314の使用
US12162851B2 (en) 2020-03-11 2024-12-10 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
BR112022017801A2 (pt) 2020-03-11 2022-10-25 Nocion Therapeutics Inc Bloqueadores de canais de íons carregados e métodos para uso
CN113509457B (zh) * 2020-09-07 2023-03-21 四川昇嘉科技有限公司 山椒素在制备治疗湿疹的药物中的用途
US11977085B1 (en) 2023-09-05 2024-05-07 Elan Ehrlich Date rape drug detection device and method of using same

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6413961B1 (en) * 1995-12-12 2002-07-02 Omeros Medical Systems, Inc. Irrigation solution and method for inhibition of pain and inflammation
AU2334501A (en) * 1999-12-15 2001-06-25 Ucb Farchim Sa Cyclic quaternary ammonium compounds
US20030027833A1 (en) * 2001-05-07 2003-02-06 Cleary Gary W. Compositions and delivery systems for administration of a local anesthetic agent
EA012599B1 (ru) * 2003-04-10 2009-10-30 Ньюроджескс, Инк. Способы и композиции для введения агонистов trpv1
ES2223277B1 (es) * 2003-06-19 2006-03-01 Fernando Bouffard Fita Composicion anestesica para administracion topica.
CN102764247B (zh) * 2004-01-30 2016-04-20 考里安国际公司 递送活性剂的快速溶解膜
ES2542847T3 (es) * 2004-06-02 2015-08-12 Neurogesx Inc. Formulaciones que comprenden capsaicina, un anestésico local y/o un agente antipruriginoso para el tratamiento del dolor
JP2010510227A (ja) * 2006-11-20 2010-04-02 プレジデント アンド フェロウズ オブ ハーバード カレッジ 痛みおよび痒みの治療方法、組成物およびキット

Also Published As

Publication number Publication date
CA2717042A1 (en) 2009-09-17
US20110086818A1 (en) 2011-04-14
CN102112121A (zh) 2011-06-29
WO2009114139A2 (en) 2009-09-17
KR20110044166A (ko) 2011-04-28
AU2009223739A1 (en) 2009-09-17
MX2010009951A (es) 2011-09-01
IL208027A0 (en) 2010-12-30
EP2271329A4 (en) 2013-01-09
WO2009114139A3 (en) 2009-12-23
JP2011513484A (ja) 2011-04-28
EP2271329A2 (en) 2011-01-12

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]