BRPI0822556B1 - Anticorpo monoclonal anti-vegf e composição farmacêutica - Google Patents
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- BRPI0822556B1 BRPI0822556B1 BRPI0822556-7A BRPI0822556A BRPI0822556B1 BR PI0822556 B1 BRPI0822556 B1 BR PI0822556B1 BR PI0822556 A BRPI0822556 A BR PI0822556A BR PI0822556 B1 BRPI0822556 B1 BR PI0822556B1
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- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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| US3971908P | 2008-03-26 | 2008-03-26 | |
| US61/039,719 | 2008-03-26 | ||
| PCT/US2008/011620 WO2009120178A1 (en) | 2008-03-26 | 2008-10-08 | Anti-vegf antibody |
Publications (2)
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| BRPI0822556A2 BRPI0822556A2 (pt) | 2020-08-18 |
| BRPI0822556B1 true BRPI0822556B1 (pt) | 2022-03-03 |
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| BR (1) | BRPI0822556B1 (OSRAM) |
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| PT2307454T (pt) | 2008-06-25 | 2017-04-26 | Esbatech Alcon Biomed Res Unit | Anticorpos estáveis e solúveis que inibem o vegf |
| CN102002104A (zh) * | 2009-08-28 | 2011-04-06 | 江苏先声药物研究有限公司 | 一种抗vegf的单克隆抗体及含有该抗体的药物组合物 |
| WO2011047442A1 (en) * | 2009-10-23 | 2011-04-28 | Garvan Institute Of Medical Research | Modified variable domain molecules and methods for producing and using same |
| BR112013021863A2 (pt) | 2011-03-03 | 2016-11-22 | Apexigen Inc | anticorpos anti-receptor il-6 e métodos de uso |
| CN104650229A (zh) * | 2011-11-02 | 2015-05-27 | 埃派斯进有限公司 | 抗-kdr抗体和使用方法 |
| CN103417964A (zh) * | 2012-05-17 | 2013-12-04 | 江苏先声药物研究有限公司 | 一种抗vegf抗体的用途 |
| CN103417965B (zh) * | 2012-05-17 | 2018-04-13 | 江苏先声药业有限公司 | 一种含有抗vegf抗体的药物组合物 |
| US9745558B2 (en) | 2013-02-18 | 2017-08-29 | Vegenics Pty Limited | VEGFR-3 ligand binding molecules and uses thereof |
| JP2016530244A (ja) * | 2013-12-31 | 2016-09-29 | ディベロップメント センター フォー バイオテクノロジーＤｅｖｅｌｏｐｍｅｎｔ Ｃｅｎｔｅｒ Ｆｏｒ Ｂｉｏｔｅｃｈｎｏｌｏｇｙ | 抗ｖｅｇｆ抗体及びその使用 |
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| GB201412658D0 (en) | 2014-07-16 | 2014-08-27 | Ucb Biopharma Sprl | Molecules |
| US20180142038A1 (en) * | 2015-01-16 | 2018-05-24 | ALDER BIOPHARMACEUTICALS, INC. a/b/a ALDERBIO HOLDINGS LLC | Anti-glycoprotein antibodies and uses thereof |
| CN107849105B (zh) * | 2015-07-06 | 2021-09-17 | Ucb生物制药有限责任公司 | Tau结合抗体 |
| GB201601073D0 (en) * | 2016-01-20 | 2016-03-02 | Ucb Biopharma Sprl | Antibodies |
| GB201601077D0 (en) | 2016-01-20 | 2016-03-02 | Ucb Biopharma Sprl | Antibody molecule |
| GB201521382D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Antibodies |
| GB201521389D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Method |
| WO2017117464A1 (en) | 2015-12-30 | 2017-07-06 | Kodiak Sciences Inc. | Antibodies and conjugates thereof |
| BR112020017872A2 (pt) | 2018-03-02 | 2020-12-22 | Kodiak Sciences Inc. | Anticorpos de il-6 e construtos de fusão e conjugados dos mesmos |
| KR20220093103A (ko) * | 2019-09-13 | 2022-07-05 | 어드메어 테라퓨틱스 소사이어티 | 항종양용해 바이러스 항원 항체 및 이의 사용 방법 |
| WO2021072265A1 (en) | 2019-10-10 | 2021-04-15 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
| IL321781A (en) * | 2022-12-29 | 2025-08-01 | Ltz Therapeutics Inc | Anti-cd79b antibodies and uses thereof |
| CN118344476B (zh) * | 2024-05-16 | 2024-11-15 | 武汉爱博泰克生物科技有限公司 | 人c反应蛋白单克隆抗体、抗体对和检测试剂或试剂盒及其应用 |
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| CN1308347C (zh) * | 1999-04-28 | 2007-04-04 | 德克萨斯大学董事会 | 用于通过选择性抑制vegf来治疗癌症的组合物和方法 |
| CN1299833A (zh) * | 1999-12-30 | 2001-06-20 | 华西医科大学口腔医学研究所 | 抗人血管内皮生长因子单链抗体及其制备方法 |
| US20040185040A1 (en) * | 2001-11-21 | 2004-09-23 | Celltech R & D Limited | Modulating immune responses |
| JP2005535341A (ja) * | 2002-08-15 | 2005-11-24 | エピトミスク インコーポレーティッド | ヒト化ウサギ抗体 |
| CA2533830A1 (en) * | 2003-08-07 | 2005-02-24 | Epitomics, Inc. | Methods for humanizing rabbit monoclonal antibodies |
| US7462697B2 (en) * | 2004-11-08 | 2008-12-09 | Epitomics, Inc. | Methods for antibody engineering |
| US7431927B2 (en) * | 2005-03-24 | 2008-10-07 | Epitomics, Inc. | TNFα-neutralizing antibodies |
| KR101834797B1 (ko) * | 2008-06-25 | 2018-03-07 | 에스바테크 - 어 노바티스 컴파니 엘엘씨 | 보편적 항체 프레임워크를 사용한 래빗 항체의 인간화 |
| CN102002104A (zh) * | 2009-08-28 | 2011-04-06 | 江苏先声药物研究有限公司 | 一种抗vegf的单克隆抗体及含有该抗体的药物组合物 |
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| CN102065888A (zh) | 2011-05-18 |
| CA2981887A1 (en) | 2009-10-01 |
| AU2008353479B2 (en) | 2014-02-20 |
| CN103992405B (zh) | 2016-08-17 |
| CA2719400A1 (en) | 2009-10-01 |
| US7803371B2 (en) | 2010-09-28 |
| BRPI0822556A2 (pt) | 2020-08-18 |
| JP2014205674A (ja) | 2014-10-30 |
| CA3053675A1 (en) | 2009-10-01 |
| US20090246190A1 (en) | 2009-10-01 |
| EP2259795A4 (en) | 2012-06-06 |
| JP5823858B2 (ja) | 2015-11-25 |
| EP2259795A1 (en) | 2010-12-15 |
| WO2009120178A1 (en) | 2009-10-01 |
| US8088375B2 (en) | 2012-01-03 |
| US20110008367A1 (en) | 2011-01-13 |
| JP2011517447A (ja) | 2011-06-09 |
| CA2719400C (en) | 2017-11-14 |
| KR20100132983A (ko) | 2010-12-20 |
| CN102065888B (zh) | 2014-03-26 |
| KR101581244B1 (ko) | 2015-12-31 |
| AU2008353479A1 (en) | 2009-10-01 |
| CA2981887C (en) | 2019-09-03 |
| CN103992405A (zh) | 2014-08-20 |
| EP2259795B1 (en) | 2016-04-06 |
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