BRPI0821514B8 - nanodispersão - Google Patents
nanodispersãoInfo
- Publication number
- BRPI0821514B8 BRPI0821514B8 BRPI0821514A BRPI0821514A BRPI0821514B8 BR PI0821514 B8 BRPI0821514 B8 BR PI0821514B8 BR PI0821514 A BRPI0821514 A BR PI0821514A BR PI0821514 A BRPI0821514 A BR PI0821514A BR PI0821514 B8 BRPI0821514 B8 BR PI0821514B8
- Authority
- BR
- Brazil
- Prior art keywords
- nanodispersion
- nanoparticles
- salts
- derivatives
- water
- Prior art date
Links
- 239000002105 nanoparticle Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 229930182558 Sterol Natural products 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- -1 acids fatty acids Chemical class 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 150000003432 sterols Chemical class 0.000 abstract 1
- 235000003702 sterols Nutrition 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Optics & Photonics (AREA)
- Nanotechnology (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN2527MU2007 | 2007-12-24 | ||
| IN2527/MUM/2007 | 2007-12-24 | ||
| PCT/IN2008/000857 WO2009087678A2 (en) | 2007-12-24 | 2008-12-23 | Nanodispersion |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0821514A2 BRPI0821514A2 (pt) | 2016-09-27 |
| BRPI0821514B1 BRPI0821514B1 (pt) | 2020-03-10 |
| BRPI0821514B8 true BRPI0821514B8 (pt) | 2021-05-25 |
Family
ID=40853553
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0821514A BRPI0821514B8 (pt) | 2007-12-24 | 2008-12-23 | nanodispersão |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US8586062B2 (enExample) |
| EP (2) | EP2231144B1 (enExample) |
| JP (2) | JP5656643B2 (enExample) |
| KR (1) | KR101505419B1 (enExample) |
| CN (1) | CN101909614B (enExample) |
| AP (1) | AP2895A (enExample) |
| AU (1) | AU2008346121B2 (enExample) |
| BR (1) | BRPI0821514B8 (enExample) |
| CA (1) | CA2710525C (enExample) |
| CO (1) | CO6290681A2 (enExample) |
| DK (1) | DK2231144T3 (enExample) |
| EA (1) | EA016434B1 (enExample) |
| ES (1) | ES2509490T3 (enExample) |
| IL (1) | IL206584A0 (enExample) |
| MX (1) | MX2010007076A (enExample) |
| NZ (1) | NZ586343A (enExample) |
| PL (1) | PL2231144T3 (enExample) |
| UA (1) | UA100543C2 (enExample) |
| WO (1) | WO2009087678A2 (enExample) |
| ZA (1) | ZA201004450B (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2010261342A1 (en) * | 2009-06-19 | 2012-01-19 | Sun Pharma Advanced Research Company Ltd., | Nanodispersion of a drug and process for its preparation |
| CN102038635A (zh) | 2009-10-23 | 2011-05-04 | 天津天士力集团有限公司 | 一种含有pH值调节剂的紫杉烷类药物溶液及其制备方法 |
| KR20110056042A (ko) * | 2009-11-20 | 2011-05-26 | 주식회사유한양행 | 종양세포 표적지향을 위한 나노 입자 및 이의 제조방법 |
| SG10201503234SA (en) | 2010-05-03 | 2015-06-29 | Teikoku Pharma Usa Inc | Non-Aqueous Taxane Pro-Emulsion Formulations and Methods of Making and Using the Same |
| ES2385995B2 (es) * | 2011-01-10 | 2013-05-21 | Universidade De Santiago De Compostela | Nanocápsulas con cubierta polimérica |
| CN102078300B (zh) * | 2011-01-27 | 2012-01-11 | 海南美大制药有限公司 | 托拉塞米脂质体固体制剂 |
| CN102366409B (zh) * | 2011-09-14 | 2013-03-20 | 海南灵康制药有限公司 | 一种尼扎替丁脂质体固体制剂 |
| JO3685B1 (ar) * | 2012-10-01 | 2020-08-27 | Teikoku Pharma Usa Inc | صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها |
| US10736327B2 (en) * | 2013-03-14 | 2020-08-11 | Griffith Foods International Inc. | Natural fungicide composition |
| US20170099833A1 (en) * | 2014-05-30 | 2017-04-13 | Oms Investments, Inc. | Nano-sized water-based dispersion compositions and methods of making thereof |
| KR101692314B1 (ko) * | 2015-03-27 | 2017-01-03 | 주식회사 주빅 | 지용성 약물의 생분해성 고분자 내 용해 시스템: 스마트 폴리머 시스템 |
| US20160346219A1 (en) | 2015-06-01 | 2016-12-01 | Autotelic Llc | Phospholipid-coated therapeutic agent nanoparticles and related methods |
| US11304898B2 (en) * | 2015-06-09 | 2022-04-19 | Sun Pharma Advanced Research Company Ltd | Method of treating carcinoma |
| CN107551390A (zh) * | 2017-08-21 | 2018-01-09 | 常熟佳禾生物科技有限公司 | 一种用于治疗乳腺小叶增生的中药文胸贴片及其制备方法 |
| WO2019182501A1 (en) | 2018-03-19 | 2019-09-26 | Epicyt Pharma Ab | A composition for use in the treatment of conditions caused by calcium deficiency |
| US11877717B2 (en) | 2019-12-17 | 2024-01-23 | Emma Ruccio | Method and apparatus for detecting scoliosis |
| US11423574B2 (en) | 2019-12-17 | 2022-08-23 | Emma Ruccio | Method and apparatus for detecting scoliosis |
| JP7745863B2 (ja) * | 2021-04-12 | 2025-09-30 | 国立大学法人広島大学 | 難水溶性物質の可溶化方法および難水溶性物質の可溶化組成物 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6018A (en) * | 1849-01-09 | Improvement in bog-cutters | ||
| US5399363A (en) * | 1991-01-25 | 1995-03-21 | Eastman Kodak Company | Surface modified anticancer nanoparticles |
| US6537579B1 (en) | 1993-02-22 | 2003-03-25 | American Bioscience, Inc. | Compositions and methods for administration of pharmacologically active compounds |
| US6753006B1 (en) | 1993-02-22 | 2004-06-22 | American Bioscience, Inc. | Paclitaxel-containing formulations |
| US6458373B1 (en) * | 1997-01-07 | 2002-10-01 | Sonus Pharmaceuticals, Inc. | Emulsion vehicle for poorly soluble drugs |
| KR19990075621A (ko) * | 1998-03-23 | 1999-10-15 | 임성주 | 경사 평판형 배양조 |
| US6017948A (en) | 1998-10-30 | 2000-01-25 | Supergen, Inc. | Water-miscible pharmaceutical compositions |
| US6365191B1 (en) * | 1999-02-17 | 2002-04-02 | Dabur Research Foundation | Formulations of paclitaxel, its derivatives or its analogs entrapped into nanoparticles of polymeric micelles, process for preparing same and the use thereof |
| US6294192B1 (en) * | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
| DE60032372T2 (de) * | 1999-09-23 | 2007-10-11 | Dabur Pharma Ltd., New Delhi | Arzneizubereitungen enthaltend paclitaxel eingeschlossen in nanopartikeln von polymerischen mizellen |
| TWI230616B (en) * | 2000-09-25 | 2005-04-11 | Ind Tech Res Inst | Liposome for incorporating large amounts of hydrophobic substances |
| WO2002087563A2 (en) * | 2001-05-01 | 2002-11-07 | Angiotech Pharmaceuticals Inc. | Compositions comprising an anti-microtubule agent and a polypeptide or a polysaccharide and the use thereof for the preparation of a medicament for the treatment of inflammatory conditions |
| DE10124952A1 (de) * | 2001-05-21 | 2002-12-12 | Bayer Ag | Verfahren zur Herstellung von Nanodispersionen |
| WO2003045357A1 (en) * | 2001-11-27 | 2003-06-05 | Transform Pharmaceuticals, Inc. | Oral pharmaceutical formulations comprising paclitaxel, derivatives and methods of administration thereof |
| US6780324B2 (en) * | 2002-03-18 | 2004-08-24 | Labopharm, Inc. | Preparation of sterile stabilized nanodispersions |
| ITMI20022323A1 (it) * | 2002-10-31 | 2004-05-01 | Maria Rosa Gasco | Composizioni farmaceutiche atte al trattamento di malattie oftalmiche. |
| US7670627B2 (en) * | 2002-12-09 | 2010-03-02 | Salvona Ip Llc | pH triggered targeted controlled release systems for the delivery of pharmaceutical active ingredients |
| US7345093B2 (en) * | 2004-04-27 | 2008-03-18 | Formatech, Inc. | Methods of enhancing solubility of compounds |
| US20050288521A1 (en) * | 2004-06-29 | 2005-12-29 | Phytogen Life Sciences Inc. | Semi-synthetic conversion of paclitaxel to docetaxel |
| BRPI0608173A2 (pt) * | 2005-02-24 | 2010-11-09 | Elan Pharma Int Ltd | composição, uso da mesma, e, método de produzir uma composição de docetaxel nanoparticulada ou análogo do mesmo |
| KR20080030024A (ko) | 2005-06-17 | 2008-04-03 | 호스피라 오스트레일리아 피티와이 리미티드 | 도세탁셀의 약제학적 액상제제 |
| CA2626016A1 (en) * | 2005-10-21 | 2007-06-21 | Panacea Biotec Limited | Pharmaceutical composition comprising at least one anticancer drug and at least one polymer |
| KR100917809B1 (ko) * | 2006-05-22 | 2009-09-18 | 에스케이케미칼주식회사 | 우수한 저장안정성을 갖는 도세탁셀 함유 주사제 조성물 |
| US20100068251A1 (en) * | 2006-10-10 | 2010-03-18 | Jina Pharmaceuticals, Inc. | Aqueous Systems For The Preparation Of Lipid Based Pharmaceutical Compounds; Compositions, Methods, And Uses Thereof |
-
2008
- 2008-12-23 CN CN200880122577.2A patent/CN101909614B/zh active Active
- 2008-12-23 PL PL08870171T patent/PL2231144T3/pl unknown
- 2008-12-23 AU AU2008346121A patent/AU2008346121B2/en active Active
- 2008-12-23 JP JP2010540226A patent/JP5656643B2/ja active Active
- 2008-12-23 US US12/810,428 patent/US8586062B2/en not_active Expired - Fee Related
- 2008-12-23 NZ NZ586343A patent/NZ586343A/en not_active IP Right Cessation
- 2008-12-23 WO PCT/IN2008/000857 patent/WO2009087678A2/en not_active Ceased
- 2008-12-23 DK DK08870171.9T patent/DK2231144T3/da active
- 2008-12-23 EP EP08870171.9A patent/EP2231144B1/en active Active
- 2008-12-23 EA EA201070793A patent/EA016434B1/ru not_active IP Right Cessation
- 2008-12-23 AP AP2010005314A patent/AP2895A/xx active
- 2008-12-23 MX MX2010007076A patent/MX2010007076A/es active IP Right Grant
- 2008-12-23 UA UAA201009239A patent/UA100543C2/ru unknown
- 2008-12-23 EP EP14175007.5A patent/EP2853264A1/en not_active Withdrawn
- 2008-12-23 BR BRPI0821514A patent/BRPI0821514B8/pt active IP Right Grant
- 2008-12-23 CA CA2710525A patent/CA2710525C/en active Active
- 2008-12-23 KR KR1020107014449A patent/KR101505419B1/ko active Active
- 2008-12-23 ES ES08870171.9T patent/ES2509490T3/es active Active
-
2010
- 2010-06-23 ZA ZA2010/04450A patent/ZA201004450B/en unknown
- 2010-06-23 IL IL206584A patent/IL206584A0/en unknown
- 2010-07-22 CO CO10089145A patent/CO6290681A2/es not_active Application Discontinuation
-
2013
- 2013-10-03 US US14/045,250 patent/US20140030352A1/en not_active Abandoned
-
2014
- 2014-11-21 JP JP2014237028A patent/JP5937180B2/ja active Active
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 10/03/2020, OBSERVADAS AS CONDICOES LEGAIS. |
|
| B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 23/12/2008 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF |