BRPI0819719A8 - compostos de inibição de dipeptidil peptidase-iv, métodos de preparação dos mesmos, e preparações farmacêuticas contendo os mesmos como agente ativo - Google Patents
compostos de inibição de dipeptidil peptidase-iv, métodos de preparação dos mesmos, e preparações farmacêuticas contendo os mesmos como agente ativoInfo
- Publication number
- BRPI0819719A8 BRPI0819719A8 BRPI0819719A BRPI0819719A BRPI0819719A8 BR PI0819719 A8 BRPI0819719 A8 BR PI0819719A8 BR PI0819719 A BRPI0819719 A BR PI0819719A BR PI0819719 A BRPI0819719 A BR PI0819719A BR PI0819719 A8 BRPI0819719 A8 BR PI0819719A8
- Authority
- BR
- Brazil
- Prior art keywords
- preparing
- methods
- active agent
- pharmaceutical preparations
- preparations containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20070134887 | 2007-12-21 | ||
| KR10-2007-0134887 | 2007-12-21 | ||
| PCT/KR2008/007543 WO2009082134A2 (en) | 2007-12-21 | 2008-12-19 | Dipeptidyl peptidase-iv inhibiting compounds, methods of preparing the same, and pharmaceutical compositions containing the same as active agent |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| BRPI0819719A2 BRPI0819719A2 (pt) | 2015-06-16 |
| BRPI0819719A8 true BRPI0819719A8 (pt) | 2015-09-22 |
| BRPI0819719B1 BRPI0819719B1 (pt) | 2020-09-24 |
| BRPI0819719B8 BRPI0819719B8 (pt) | 2021-05-25 |
Family
ID=40801676
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0819719A BRPI0819719B8 (pt) | 2007-12-21 | 2008-12-19 | compostos de inibição de dipeptidil peptidase-iv, métodos de preparação dos mesmos, e preparações farmacêuticas contendo os mesmos como agente ativo |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8470836B2 (pt) |
| EP (1) | EP2220086A4 (pt) |
| JP (1) | JP5358585B2 (pt) |
| KR (1) | KR101105607B1 (pt) |
| CN (1) | CN101903386B (pt) |
| AU (1) | AU2008341352B2 (pt) |
| BR (1) | BRPI0819719B8 (pt) |
| CA (1) | CA2710109C (pt) |
| CO (1) | CO6300861A2 (pt) |
| EA (1) | EA201070635A1 (pt) |
| MA (1) | MA31919B1 (pt) |
| UA (1) | UA103181C2 (pt) |
| WO (1) | WO2009082134A2 (pt) |
| ZA (1) | ZA201004214B (pt) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
| US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
| TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
| TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
| TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
| PT2611776T (pt) * | 2010-09-03 | 2016-12-20 | Lg Life Sciences Ltd | Método de produção de composto intermediário para sintetizar o medicamento |
| CN102617566B (zh) * | 2011-01-30 | 2015-03-04 | 山东轩竹医药科技有限公司 | 吡啶并咪唑烷衍生物 |
| CN102875567B (zh) * | 2011-07-15 | 2015-03-11 | 天津药物研究院 | 一类含哌嗪化合物、制备及用途 |
| WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| EP2760862B1 (en) | 2011-09-27 | 2015-10-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| WO2013115595A1 (ko) * | 2012-02-03 | 2013-08-08 | 주식회사 엘지생명과학 | 물 또는 다양한 산을 첨가제로 이용한 새로운 마이클-첨가 반응을 통하여 화합물을 제조하는 방법 |
| IN2015DN03795A (pt) | 2012-10-24 | 2015-10-02 | Inserm Inst Nat De La Santé Et De La Rech Médicale | |
| CN105017244A (zh) * | 2014-04-16 | 2015-11-04 | 上海药明康德新药开发有限公司 | 顺反叔丁基-4-氧六氢化-1H-吡咯[3,4-c]吡啶-2(3H)-羧酸叔丁酯的合成方法 |
| CN104447511A (zh) * | 2014-11-12 | 2015-03-25 | 江苏中邦制药有限公司 | 一种n-叔丁氧羰基-3-哌啶酮的合成方法 |
| US10426818B2 (en) | 2015-03-24 | 2019-10-01 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Method and pharmaceutical composition for use in the treatment of diabetes |
| PE20210839A1 (es) * | 2017-11-16 | 2021-05-06 | Lg Chemical Ltd | Metodo de produccion de un compuesto intermedio para sintetizar un medicamento |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CO5150173A1 (es) | 1998-12-10 | 2002-04-29 | Novartis Ag | Compuestos n-(glicilo sustituido)-2-cianopirrolidinas inhibidores de peptidasa de dipeptidilo-iv (dpp-iv) los cuales son efectivos en el tratamiento de condiciones mediadas por la inhibicion de dpp-iv |
| UA74912C2 (en) | 2001-07-06 | 2006-02-15 | Merck & Co Inc | Beta-aminotetrahydroimidazo-(1,2-a)-pyrazines and tetratriazolo-(4,3-a)-pyrazines as inhibitors of dipeptylpeptidase for the treatment or prevention of diabetes |
| US6861440B2 (en) * | 2001-10-26 | 2005-03-01 | Hoffmann-La Roche Inc. | DPP IV inhibitors |
| EP1490335B1 (en) | 2002-03-25 | 2007-09-19 | Merck & Co., Inc. | Beta-amino heterocyclic dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes |
| JP4564952B2 (ja) * | 2003-01-17 | 2010-10-20 | メルク・シャープ・エンド・ドーム・コーポレイション | 糖尿病の治療および予防のためのジペプチジルペプチダーゼ阻害薬としての３−アミノ−４−フェニルブタン酸誘導体 |
| WO2004089362A1 (en) * | 2003-04-11 | 2004-10-21 | Novo Nordisk A/S | 2-cyanopyrroles and their analogues as ddp-iv inhibitors |
| TWI357902B (en) * | 2005-04-01 | 2012-02-11 | Lg Life Science Ltd | Dipeptidyl peptidase-iv inhibiting compounds, meth |
-
2008
- 2008-12-19 BR BRPI0819719A patent/BRPI0819719B8/pt active IP Right Grant
- 2008-12-19 EP EP08863947A patent/EP2220086A4/en not_active Withdrawn
- 2008-12-19 JP JP2010539306A patent/JP5358585B2/ja active Active
- 2008-12-19 EA EA201070635A patent/EA201070635A1/ru unknown
- 2008-12-19 CA CA2710109A patent/CA2710109C/en active Active
- 2008-12-19 AU AU2008341352A patent/AU2008341352B2/en active Active
- 2008-12-19 US US12/747,860 patent/US8470836B2/en active Active
- 2008-12-19 CN CN200880121980.3A patent/CN101903386B/zh active Active
- 2008-12-19 WO PCT/KR2008/007543 patent/WO2009082134A2/en active Application Filing
- 2008-12-19 UA UAA201007683A patent/UA103181C2/ru unknown
- 2008-12-19 KR KR1020080129930A patent/KR101105607B1/ko active Protection Beyond IP Right Term
-
2010
- 2010-06-14 ZA ZA2010/04214A patent/ZA201004214B/en unknown
- 2010-06-15 MA MA32919A patent/MA31919B1/fr unknown
- 2010-06-21 CO CO10074430A patent/CO6300861A2/es active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| ZA201004214B (en) | 2011-04-28 |
| CA2710109C (en) | 2016-07-19 |
| MA31919B1 (fr) | 2010-12-01 |
| BRPI0819719B8 (pt) | 2021-05-25 |
| CO6300861A2 (es) | 2011-07-21 |
| WO2009082134A2 (en) | 2009-07-02 |
| CN101903386A (zh) | 2010-12-01 |
| UA103181C2 (ru) | 2013-09-25 |
| AU2008341352B2 (en) | 2013-08-01 |
| US20100274013A1 (en) | 2010-10-28 |
| EP2220086A2 (en) | 2010-08-25 |
| BRPI0819719B1 (pt) | 2020-09-24 |
| EA201070635A1 (ru) | 2010-12-30 |
| KR20090068156A (ko) | 2009-06-25 |
| CA2710109A1 (en) | 2009-07-02 |
| WO2009082134A3 (en) | 2009-09-24 |
| JP2011507832A (ja) | 2011-03-10 |
| JP5358585B2 (ja) | 2013-12-04 |
| EP2220086A4 (en) | 2010-12-22 |
| AU2008341352A1 (en) | 2009-07-02 |
| CN101903386B (zh) | 2015-04-22 |
| BRPI0819719A2 (pt) | 2015-06-16 |
| US8470836B2 (en) | 2013-06-25 |
| KR101105607B1 (ko) | 2012-01-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
| B25A | Requested transfer of rights approved |
Owner name: LG CHEM, LTD. (KR) |
|
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 24/09/2020, OBSERVADAS AS CONDICOES LEGAIS. |
|
| B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 19/12/2008 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF |