BRPI0819717A2 - Produção de ácido dicarboxílico em uma levedura recombinante - Google Patents

Produção de ácido dicarboxílico em uma levedura recombinante

Info

Publication number
BRPI0819717A2
BRPI0819717A2 BRPI0819717-2A2A BRPI0819717A BRPI0819717A2 BR PI0819717 A2 BRPI0819717 A2 BR PI0819717A2 BR PI0819717 A BRPI0819717 A BR PI0819717A BR PI0819717 A2 BRPI0819717 A2 BR PI0819717A2
Authority
BR
Brazil
Prior art keywords
dicarboxylic acid
acid production
recombinant yeast
yeast
recombinant
Prior art date
Application number
BRPI0819717-2A2A
Other languages
English (en)
Inventor
Rene Verwaal
Liang Wu
Robbertus Antonius Damveld
Cornelis Maria Jacobus Sagt
Original Assignee
Dsm Ip Assets Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv
Publication of BRPI0819717A2 publication Critical patent/BRPI0819717A2/pt
Publication of BRPI0819717B1 publication Critical patent/BRPI0819717B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BRPI0819717-2A 2007-11-20 2008-11-14 Levedura recombinante e processo para a produção de ácido succínico BRPI0819717B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP07121117.1 2007-11-20
EP07121117 2007-11-20
EP08156960 2008-05-27
EP08156960.0 2008-05-27
PCT/EP2008/065587 WO2009065779A1 (en) 2007-11-20 2008-11-14 Dicarboxylic acid production in a recombinant yeast

Publications (2)

Publication Number Publication Date
BRPI0819717A2 true BRPI0819717A2 (pt) 2014-10-14
BRPI0819717B1 BRPI0819717B1 (pt) 2022-05-17

Family

ID=40276267

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0819717-2A BRPI0819717B1 (pt) 2007-11-20 2008-11-14 Levedura recombinante e processo para a produção de ácido succínico

Country Status (6)

Country Link
US (2) US8735112B2 (pt)
EP (1) EP2220234B1 (pt)
CN (1) CN101896606B (pt)
BR (1) BRPI0819717B1 (pt)
ES (1) ES2389989T3 (pt)
WO (1) WO2009065779A1 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101896606B (zh) * 2007-11-20 2016-12-21 帝斯曼知识产权资产管理有限公司 在重组酵母中生产二羧酸
US20110318795A1 (en) * 2007-11-20 2011-12-29 Verwaal Rene Dicarboxylic acid production in a filamentous fungus
EP2419518A1 (en) 2009-04-15 2012-02-22 DSM IP Assets B.V. Dicarboxylic acid production process
JP5857954B2 (ja) 2010-03-09 2016-02-10 三菱化学株式会社 コハク酸の製造方法
EP2619314A1 (en) 2010-09-24 2013-07-31 DSM IP Assets B.V. Dicarboxylic acid production process
EP2668281A4 (en) 2011-01-25 2015-08-26 Cargill Inc COMPOSITIONS AND METHODS OF SUCCINATE MANUFACTURE
BR112013033760B1 (pt) 2011-07-01 2020-10-27 Dsm Ip Assets B.V. processo de produção de ácido dicarboxílico
WO2013112939A2 (en) * 2012-01-25 2013-08-01 Cargill, Incorporated Methods for succinate production
FR2987678B1 (fr) 2012-03-02 2016-04-15 Roquette Freres Methode de mesure de la stabilite thermique d'un acide succinique cristallin destine a la fabrication de polymeres
US9085784B1 (en) 2012-03-29 2015-07-21 Newlight Technologies, Llc Polyhydroxyalkanoate production methods and materials and microorganisms used in same
BR112015001601A2 (pt) 2012-07-25 2017-11-07 Bioamber Sas células de levedura tendo curso de tca redutor de piruvato em succinato e superexpressão de uma enzima transidrogenase nad(p)+ exógena
CN104812889B (zh) * 2012-09-14 2018-08-28 麦兰特公司 通过在低ph下发酵产生有机酸
US10033004B2 (en) 2015-06-01 2018-07-24 Universal Display Corporation Organic electroluminescent materials and devices
WO2017050815A1 (en) * 2015-09-21 2017-03-30 Purac Biochem B.V. Fungal production of fdca
ES2940213T3 (es) * 2015-12-23 2023-05-04 Technip Energies France Células huésped para la producción de ácido dicarboxílico
CN105754963A (zh) * 2016-05-19 2016-07-13 江南大学 一种提高延胡索酸产量的方法
EP3919615A1 (en) 2016-07-13 2021-12-08 DSM IP Assets B.V. Malate dehyrogenases
CN110734865B (zh) * 2019-12-02 2022-11-01 南京昊禾生物科技有限公司 一种低pH条件下高产苹果酸的黑曲霉基因工程菌株及应用

Family Cites Families (21)

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Publication number Priority date Publication date Assignee Title
DE3542861A1 (de) 1985-12-04 1987-06-11 Huels Chemische Werke Ag Verfahren zur gewinnung von l-aepfelsaeure
US5643758A (en) * 1987-03-10 1997-07-01 New England Biolabs, Inc. Production and purification of a protein fused to a binding protein
WO1990014423A1 (en) 1989-05-18 1990-11-29 The Infergene Company Microorganism transformation
IE81016B1 (en) 1989-07-07 1999-09-22 Unilever Plc Process for preparing a protein by a fungus transformed by a multicopy integration of an expression vector
ATE238425T1 (de) 1993-07-23 2003-05-15 Dsm Nv Selektionmarker-genfreie rekombinante stämme: verfahren zur ihrer herstellung und die verwendung dieser stämme
US5869301A (en) * 1995-11-02 1999-02-09 Lockhead Martin Energy Research Corporation Method for the production of dicarboxylic acids
JP5303084B2 (ja) 1997-04-11 2013-10-02 コニンクリーケ デーエスエム ナムローゼ フェンノートシャップ 工業的組み換え生物を溝築するための手段としての遺伝子変換
US6265186B1 (en) 1997-04-11 2001-07-24 Dsm N.V. Yeast cells comprising at least two copies of a desired gene integrated into the chromosomal genome at more than one non-ribosomal RNA encoding domain, particularly with Kluyveromyces
CN100390285C (zh) 1998-05-19 2008-05-28 Dsm公司 体内生产头孢菌素的改良
JP2002533092A (ja) 1998-12-22 2002-10-08 デーエスエム・ナムローゼ・フェンノートシャップ セファロスポリンの改良されたｉｎｖｉｖｏ産生
CN100575496C (zh) 2003-08-28 2009-12-30 三菱化学株式会社 产生琥珀酸的方法
BRPI0519174A2 (pt) 2004-12-22 2008-12-30 Michigan Biotech Inst cepa recombinante de um microorganismo produtor de Ácido succÍnico, mÉtodo para produzir Ácido succÍnico, molÉcula de dna, plasmÍdeo de dna, e, cÉlula hospedeira
US7435168B2 (en) 2005-01-14 2008-10-14 Archer-Daniels-Midland Company Compositions and methods for manipulating carbon flux in cells
CA2618694A1 (en) 2005-08-05 2007-02-15 Michigan State University Genes from actinobacillus succinogenes 13oz (atcc 55618) for production of chemicals from the a. succinogenes c4-pathway
KR100727054B1 (ko) * 2005-08-19 2007-06-12 한국과학기술원 푸마레이트 하이드라타제 ｃ를 코딩하는 유전자로 형질전환된 재조합 미생물 및 이를 이용한 숙신산의 제조방법
CN101300356A (zh) 2005-09-09 2008-11-05 基因组股份公司 用于琥珀酸盐之生长关联性生产的方法和生物
US20080090273A1 (en) 2005-11-21 2008-04-17 Aaron Adriaan Winkler Malic Acid Production in Recombinant Yeast
EP1867727A1 (en) 2006-06-15 2007-12-19 Danmarks Tekniske Universitet Enhanced citrate production
US20110045559A1 (en) 2007-05-18 2011-02-24 Aaron Adriaan Winkler Malic acid production in recombinant yeast
EP2158323A4 (en) 2007-05-18 2011-06-22 Microbia Prec Engineering Inc PRODUCTION OF ORGANIC ACID BY PILZ CELLS
CN101896606B (zh) * 2007-11-20 2016-12-21 帝斯曼知识产权资产管理有限公司 在重组酵母中生产二羧酸

Also Published As

Publication number Publication date
EP2220234B1 (en) 2012-06-27
US20110143405A1 (en) 2011-06-16
CN101896606B (zh) 2016-12-21
EP2220234A1 (en) 2010-08-25
US8735112B2 (en) 2014-05-27
BRPI0819717B1 (pt) 2022-05-17
CN101896606A (zh) 2010-11-24
ES2389989T3 (es) 2012-11-05
US20140065680A1 (en) 2014-03-06
WO2009065779A1 (en) 2009-05-28
US9556459B2 (en) 2017-01-31

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 14/11/2008, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO.

B25A Requested transfer of rights approved

Owner name: TECHNIP ENERGIES FRANCE (FR)