BRPI0815634A2 - Identificação de receptores t2r humanos que respodem a compostos amargos que causam gosto amargo nas composições, e seu uso em ensaios para identificar compostos que inibem (bloqueiam) o gosto amargo em composições e seu uso - Google Patents

Identificação de receptores t2r humanos que respodem a compostos amargos que causam gosto amargo nas composições, e seu uso em ensaios para identificar compostos que inibem (bloqueiam) o gosto amargo em composições e seu uso

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Publication number
BRPI0815634A2
BRPI0815634A2 BRPI0815634-4A2A BRPI0815634A BRPI0815634A2 BR PI0815634 A2 BRPI0815634 A2 BR PI0815634A2 BR PI0815634 A BRPI0815634 A BR PI0815634A BR PI0815634 A2 BRPI0815634 A2 BR PI0815634A2
Authority
BR
Brazil
Prior art keywords
compositions
taste
bitter
receivers
respond
Prior art date
Application number
BRPI0815634-4A2A
Other languages
English (en)
Inventor
Xiaodong Li
Andrew Patron
Catherine Tachdjian
Hong Xu
Qing Li
Alexey Pronin
Guy Servant
Thomas Brady
Vincent Darmohusodo
Melissa Arellano
Victor Selchau
Brett Weylan Ching
Donald S Karanewsky
Paul Brust
Jing Ling
Wen Zhao
Chad Priest
Lan Zhang
Original Assignee
Senomyx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senomyx Inc filed Critical Senomyx Inc
Publication of BRPI0815634A2 publication Critical patent/BRPI0815634A2/pt
Publication of BRPI0815634B1 publication Critical patent/BRPI0815634B1/pt

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    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • C07C311/17—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
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    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
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CL2008002473A1 (es) 2009-03-27
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EP2487169A1 (en) 2012-08-15
EP2487169B1 (en) 2015-05-20
CN104130247A (zh) 2014-11-05
EP2195656A4 (en) 2011-10-19
EP2195656A2 (en) 2010-06-16
KR101558193B1 (ko) 2015-10-12
CN104130247B (zh) 2018-06-01
WO2009025793A2 (en) 2009-02-26
AU2008289485A1 (en) 2009-02-26
US20110207937A1 (en) 2011-08-25
MX2010001995A (es) 2010-06-09
BRPI0815634B1 (pt) 2024-01-09
US20130183252A1 (en) 2013-07-18
KR101599715B1 (ko) 2016-03-08
CA2696995A1 (en) 2009-02-26
CA2696995C (en) 2017-11-21
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US8148544B2 (en) 2012-04-03
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AU2008289485B2 (en) 2014-08-14
US7939671B2 (en) 2011-05-10
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