BRPI0815410A2 - Processos para purificar ou detectar uma proteína alvo presente em uma solução e para purificar e para detectar especificamente uma proetína alvo a partir de uma solução. - Google Patents

Processos para purificar ou detectar uma proteína alvo presente em uma solução e para purificar e para detectar especificamente uma proetína alvo a partir de uma solução.

Info

Publication number
BRPI0815410A2
BRPI0815410A2 BRPI0815410-4A2A BRPI0815410A BRPI0815410A2 BR PI0815410 A2 BRPI0815410 A2 BR PI0815410A2 BR PI0815410 A BRPI0815410 A BR PI0815410A BR PI0815410 A2 BRPI0815410 A2 BR PI0815410A2
Authority
BR
Brazil
Prior art keywords
purifying
solution
target protein
detecting
processes
Prior art date
Application number
BRPI0815410-4A2A
Other languages
English (en)
Inventor
Laurent Siret
Abdessatar Chtourou
Frederic Dhainaut
Gerald Perret
Original Assignee
Lfb Biotechnologies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lfb Biotechnologies filed Critical Lfb Biotechnologies
Publication of BRPI0815410A2 publication Critical patent/BRPI0815410A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6437—Coagulation factor VIIa (3.4.21.21)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21021—Coagulation factor VIIa (3.4.21.21)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745—Assays involving non-enzymic blood coagulation factors
    • G01N2333/755—Factors VIII, e.g. factor VIII C [AHF], factor VIII Ag [VWF]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/974—Thrombin
BRPI0815410-4A2A 2007-08-14 2008-08-13 Processos para purificar ou detectar uma proteína alvo presente em uma solução e para purificar e para detectar especificamente uma proetína alvo a partir de uma solução. BRPI0815410A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0757072A FR2920024B1 (fr) 2007-08-14 2007-08-14 Procede de purification ou de detection d'une proteine cible
PCT/FR2008/051495 WO2009024726A2 (fr) 2007-08-14 2008-08-13 Procede de purification ou de detection d'une proteine cible

Publications (1)

Publication Number Publication Date
BRPI0815410A2 true BRPI0815410A2 (pt) 2015-02-03

Family

ID=39321464

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0815410-4A2A BRPI0815410A2 (pt) 2007-08-14 2008-08-13 Processos para purificar ou detectar uma proteína alvo presente em uma solução e para purificar e para detectar especificamente uma proetína alvo a partir de uma solução.

Country Status (12)

Country Link
US (2) US9175034B2 (pt)
EP (2) EP2508533B1 (pt)
JP (2) JP6006472B2 (pt)
KR (2) KR20100058479A (pt)
CN (2) CN101821282A (pt)
AR (1) AR067924A1 (pt)
AU (1) AU2008290416B2 (pt)
BR (1) BRPI0815410A2 (pt)
CA (1) CA2696363A1 (pt)
ES (2) ES2599303T3 (pt)
FR (1) FR2920024B1 (pt)
WO (1) WO2009024726A2 (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2942231B1 (fr) * 2009-02-19 2015-03-20 Lfb Biotechnologies Acides nucleiques se liant specifiquement au facteur vii/viia humain, et utilisations
FR2942232B1 (fr) * 2009-02-19 2015-03-13 Lfb Biotechnologies Moyens pour la purification d'une proteine de la coagulation et procedes pour sa mise en oeuvre
JP5691161B2 (ja) * 2009-11-19 2015-04-01 Jnc株式会社 タンパク質の精製方法
US8785132B2 (en) * 2010-04-23 2014-07-22 Postech Academy-Industry Foundation Aptamer sandwich assays
BR112013016704A2 (pt) * 2010-12-30 2017-03-14 Laboratoire Français Du Fractionnement Et Des Biotechnologies método para imobilizar os ligandos nucléicos.
FR2981651B1 (fr) * 2011-10-24 2015-06-19 Lfb Biotechnologies Procede d'immobilisation de ligands nucleiques.
CN102965378B (zh) * 2012-11-14 2014-10-15 广西安仁欣生物科技有限公司 一种糖化血红蛋白的核酸适体及其制备方法
CN104164436B (zh) * 2012-11-14 2016-10-05 广西安仁欣生物科技有限公司 一种糖化血红蛋白的核酸适体及其制备方法
CN104109674B (zh) * 2012-11-14 2016-07-06 广西安仁欣生物科技有限公司 一种糖化血红蛋白的核酸适体及其制备方法
CN104109675B (zh) * 2012-11-14 2016-07-06 广西安仁欣生物科技有限公司 一种糖化血红蛋白的核酸适体及其制备方法
JP6646310B2 (ja) * 2015-05-08 2020-02-14 学校法人日本大学 標識ペプチドおよびその使用
FR3054039B1 (fr) * 2016-07-12 2020-05-29 Universite De Montpellier Biocapteur pour detecter la presence de bacteries
CN112805384A (zh) * 2018-07-17 2021-05-14 华盛顿大学 涉及基于适体的可逆细胞选择的组合物和方法
US11421234B2 (en) * 2019-12-02 2022-08-23 Chang Gung University Aptamers for targeting coagulation factor XIII and uses thereof

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2874751B2 (ja) 1986-04-09 1999-03-24 ジェンザイム・コーポレーション 希望する蛋白質をミルク中へ分泌する遺伝子移植動物
WO1991019813A1 (en) 1990-06-11 1991-12-26 The University Of Colorado Foundation, Inc. Nucleic acid ligands
US5965789A (en) * 1991-01-11 1999-10-12 American Red Cross Engineering protein posttranslational modification by PACE/furin in transgenic non-human mammals
FR2677652B1 (fr) 1991-06-12 2005-05-27 Agronomique Inst Nat Rech Procede de preparation d'une proteine d'interet dans le lait d'un animal transgenique, produit obtenu et cellule eucaryote utilisee.
US5288853A (en) * 1992-04-30 1994-02-22 Alpha Therapeutic Corporation Factor viii purification process
DE69333961T2 (de) 1992-09-29 2006-08-24 Gilead Sciences, Inc., Foster City Nukleinsäureliganden und ihre herstellungsmethoden
US5880327A (en) * 1994-09-21 1999-03-09 American National Red Cross Transgenic mammals expressing human coagulation factor VIII
CA2220109A1 (en) * 1995-05-04 1996-11-07 American Red Cross Engineering protein posttranslational modification in transgenic organisms
DE69627333T2 (de) * 1995-06-26 2004-02-12 PerSeptive Biosystems, Inc., Framingham Automatisierte, kontinuierliche mehrdimensionale hochgeschwindigkeitsmolekularselektion und -analyse
US20060057573A1 (en) * 2002-02-15 2006-03-16 Somalogic, Inc Methods and reagents for detecting target binding by nucleic acid ligands
EP2322648A1 (en) * 2000-09-26 2011-05-18 Duke University RNA aptamers and methods for identifying the same
EP1730158A2 (en) * 2003-08-06 2006-12-13 Cygene, Inc. Methods and compositions for in vitro and in vivo use of parallel stranded hairpins and triplex structures as nucleic acid ligands
US7329742B2 (en) * 2003-09-04 2008-02-12 The Regents Of The University Of California Aptamers and methods for their in vitro selection and uses thereof
CA2574090A1 (en) * 2004-07-18 2006-12-21 Coley Pharmaceutical Group, Ltd. Methods and compositions for inducing innate immune responses
KR20080036595A (ko) 2005-07-05 2008-04-28 가부시키가이샤 리보믹 면역글로불린 ｇ에 결합하는 핵산과 그 이용법

Also Published As

Publication number Publication date
CN105859829A (zh) 2016-08-17
KR20100058479A (ko) 2010-06-03
CA2696363A1 (fr) 2009-02-26
ES2599303T3 (es) 2017-02-01
US20160009761A1 (en) 2016-01-14
JP6006472B2 (ja) 2016-10-12
WO2009024726A3 (fr) 2009-04-30
EP2508533B1 (fr) 2016-08-03
EP2178901B1 (fr) 2017-05-10
AR067924A1 (es) 2009-10-28
FR2920024B1 (fr) 2012-12-14
FR2920024A1 (fr) 2009-02-20
EP2508533A1 (fr) 2012-10-10
US20110097715A1 (en) 2011-04-28
US9175034B2 (en) 2015-11-03
ES2636453T3 (es) 2017-10-05
KR20160052796A (ko) 2016-05-12
JP2016117746A (ja) 2016-06-30
AU2008290416A1 (en) 2009-02-26
CN101821282A (zh) 2010-09-01
AU2008290416B2 (en) 2013-11-21
JP2010535853A (ja) 2010-11-25
WO2009024726A2 (fr) 2009-02-26
EP2178901A2 (fr) 2010-04-28

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES BIOT

B07D Technical examination (opinion) related to article 229 of industrial property law
B07E Notice of approval relating to section 229 industrial property law

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06F Objections, documents and/or translations needed after an examination request according art. 34 industrial property law
B07A Technical examination (opinion): publication of technical examination (opinion)
B09B Decision: refusal